Synthesis, antimicrobial and cytotoxic activities of novel 4-trifluoromethyl-(1,2,3)-thiadiazolo-5-carboxylic acid hydrazide Schiff's bases

Medicinal Chemistry Research

Volumn 22, Issue 4, 2013, Pages 1747-1755

  Sambasiva Rao, P ^a   Kurumurthy, C ^a   Veeraswamy, B ^a   Santhosh Kumar, G ^a   Narsaiah, B ^a   Pranay Kumar, K ^a   Murthy, U S N ^a   Karnewar, Santosh ^a   Kotamraju, Srigiridhar ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

1,2,3 Thiadiazole; Antibacterial activity; Antifungal activity; Cytotoxic activity; Hurd Mori synthesis; Schiff's bases

Indexed keywords

4 TRIFLUOROMETHYL(1,2,3)THIADIAZOLO 5 CARBOXYLIC ACID HYDRAZIDE; AMPHOTERICIN B; ANTIINFECTIVE AGENT; CYTOTOXIC AGENT; DOXORUBICIN; HYDRAZIDE DERIVATIVE; N' (1 METHYLETHYLIDENE) 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' (1 PHENYLETHYLIDENE) 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' (FURAN 2 YLMETHYLIDENE) 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' (PHENYLMETHYLIDENE) 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' (THIOPHENE 2 YLMETHYLIDENE) 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [(4 BROMOPHENYL)METHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [(4 CHLOROPHENYL)METHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [(4 FLUOROPHENYL)METHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [(4 HYDROXYPHENYL)METHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [(4 METHOXYPHENYL)METHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [(4 NITROPHENYL)METHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [1 (2,4 DIBROMOPHENYL)ETHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [1 (4 NITROPHENYL)ETHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [1 (PYRIDINE 2 YL)ETHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N' [[4 (DIMETHYLAMINO)PHENYL]METHYLIDENE] 4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE; N',N'' HEPTANE 1,7 DIYLIDENEBIS[4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE]; N',N'' PENTANE 1,5 DIYLIDENEBIS[4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5-CARBOHYDRAZIDE]; N,N'' HEXANE 1,6 DIYLIDENEBIS[4 (TRIFLUOROMETHYL) 1,2,3 THIADIAZOLE 5 CARBOHYDRAZIDE]; PENICILLIN DERIVATIVE; SCHIFF BASE; STREPTOMYCIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BREAST CARCINOMA; CANDIDA ALBICANS; CELL VIABILITY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; FUNGAL STRAIN; HUMAN; HUMAN CELL; NONHUMAN;

EID: 84879693630     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0168-x     Document Type: Article

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