Analysis of TNF-mediated recruitment and activation of glomerular dendritic cells in mouse kidneys by compartment-specific flow cytometry

Kidney International

Volumn 84, Issue 1, 2013, Pages 116-129

  Schwarz, Martin ^a   Taubitz, Anela ^a   Eltrich, Nuru ^a   Mulay, Shrikant R ^a   Allam, Ramanjaneyulu ^a,b   Vielhauer, Volker ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE; GLYCOPROTEIN P 15095; INTERCELLULAR ADHESION MOLECULE 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CELL MATURATION; DENDRITIC CELL; FEMALE; FLOW CYTOMETRY; GLOMERULUS; IMMUNE COMPLEX DEPOSITION; IMMUNOSTIMULATION; KIDNEY INTERSTITIUM; LYMPHOCYTIC INFILTRATION; MALE; MONONUCLEAR PHAGOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; UPREGULATION;

EID: 84879690848     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.46     Document Type: Article

References (49)

1. Nelson PJ, Rees AJ, Griffin MD et al. The renal mononuclear phagocytic system. J Am Soc Nephrol 2012; 23: 194-203.
2. Hart DN, Fabre JW. Major histocompatibility complex antigens in rat kidney, ureter, and bladder. Localization with monoclonal antibodies and demonstration of Ia-positive dendritic cells. Transplantation 1981; 31: 318-325.
3. Kaissling B, Le Hir M. Characterization and distribution of interstitial cell types in the renal cortex of rats. Kidney Int 1994; 45: 709-720.
4. Kaissling B, Hegyi I, Loffing J et al. Morphology of interstitial cells in the healthy kidney. Anat Embryol (Berl) 1996; 193: 303-318.
5. Austyn JM, Hankins DF, Larsen CP et al. Isolation and characterization of dendritic cells from mouse heart and kidney. J Immunol 1994; 152: 2401-2410.
6. Roake JA, Rao AS, Morris PJ et al. Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1. J Exp Med 1995; 181: 2237-2247.
7. Krüger T, Benke D, Eitner F et al. Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis. J Am Soc Nephrol 2004; 15: 613-621.
8. Soos TJ, Sims TN, Barisoni L et al. CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney. Kidney Int 2006; 70: 591-596.
9. Kurts C, Heymann F, Lukacs-Kornek V et al. Role of T cells and dendritic cells in glomerular immunopathology. Semin Immunopathol 2007; 29: 317-335.
10. Kurts C, Heath WR, Carbone FR et al. Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med 1996; 184: 923-930.
11. Lukacs-Kornek V, Burgdorf S, Diehl L et al. The kidney-renal lymph nodesystem contributes to cross-tolerance against innocuous circulating antigen. J Immunol 2008; 180: 706-715.
12. Edgtton KL, Kausman JY, Li M et al. Intrarenal antigens activate CD4+ cells via co-stimulatory signals from dendritic cells. J Am Soc Nephrol 2008; 19: 515-526.
13. Dong X, Swaminathan S, Bachman LA et al. Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury. Kidney Int 2007; 71: 619-628.
14. Dong X, Bachman LA, Miller MN et al. Dendritic cells facilitate accumulation of IL-17 T cells in the kidney following acute renal obstruction. Kidney Int 2008; 74: 1294-1309.
15. Scholz J, Lukacs-Kornek V, Engel DR et al. Renal dendritic cells stimulate IL-10 production and attenuate nephrotoxic nephritis. J Am Soc Nephrol 2008; 19: 527-537.
16. Hochheiser K, Engel DR, Hammerich L et al. Kidney dendritic cells become pathogenic during crescentic glomerulonephritis with proteinuria. J Am Soc Nephrol 2011; 22: 306-316.
17. Bagavant H, Deshmukh US, Wang H et al. Role for nephritogenic T cells in lupus glomerulonephritis: progression to renal failure is accompanied by T cell activation and expansion in regional lymph nodes. J Immunol 2006; 177: 8258-8265.
18. Tucci M, Quatraro C, Lombardi L et al. Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin- 18. Arthritis Rheum 2008; 58: 251-262.
19. Woltman AM, de Fijter JW, Zuidwijk K et al. Quantification of dendritic cell subsets in human renal tissue under normal and pathological conditions. Kidney Int 2007; 71: 1001-1008.
20. Segerer S, Heller F, Lindenmeyer MT et al. Compartment specific expression of dendritic cell markers in human glomerulonephritis. Kidney Int 2008; 74: 37-46.
21. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245-252.
22. Le Hir M, Haas C, Marino M et al. Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice. Lab Invest 1998; 78: 1625-1631.
23. Vielhauer V, Stavrakis G, Mayadas TN. Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis. J Clin Invest 2005; 115: 1199-1209.
24. Takemoto M, Asker N, Gerhardt H et al. A new method for large scale isolation of kidney glomeruli from mice. Am J Pathol 2002; 161: 799-805.
25. Masaki T, Chow F, Nikolic-Paterson DJ et al. Heterogeneity of antigen expression explains controversy over glomerular macrophage accumulation in mouse glomerulonephritis. Nephrol Dial Transplant 2003; 18: 178-181.
26. Macconi D, Chiabrando C, Schiarea S et al. Proteasomal processing of albumin by renal dendritic cells generates antigenic peptides. J Am Soc Nephrol 2009; 20: 123-130.
27. Heymann F, Meyer-Schwesinger C, Hamilton-Williams EE et al. Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury. J Clin Invest 2009; 119: 1286-1297.
28. Schreiner GF, Kiely JM, Cotran RS et al. Characterization of resident glomerular cells in the rat expressing Ia determinants and manifesting genetically restricted interactions with lymphocytes. J Clin Invest 1981; 68: 920-931.
29. Schreiner GF, Cotran RS. Localization of an Ia-bearing glomerular cell in the mesangium. J Cell Biol 1982; 94: 483-488.
30. Schreiner GF, Unanue ER. Origin of the rat mesangial phagocyte and its expression of the leukocyte common antigen. Lab Invest 1984; 51: 515-523.
31. Gieseler R, Hoffmann PR, Kuhn R et al. Enrichment and characterization of dendritic cells from rat renal mesangium. Scand J Immunol 1997; 46: 587-596.
32. Dong X, Swaminathan S, Bachman LA et al. Antigen presentation by dendritic cells in renal lymph nodes is linked to systemic and local injury to the kidney. Kidney Int 2005; 68: 1096-1108.
33. Singh-Jasuja H, Thiolat A, Ribon M et al. The mouse dendritic cell marker CD11c is down-regulated upon cell activation through Toll-like receptor triggering. Immunobiology 2013; 218: 28-39.
34. Kluth DC, Erwig LP, Rees AJ. Multiple facets of macrophages in renal injury. Kidney Int 2004; 66: 542-557.
35. Holdsworth SR, Tipping PG. Leukocytes in glomerular injury. Semin Immunopathol 2007; 29: 355-374.
36. Cook HT, Smith J, Salmon JA et al. Functional characteristics of macrophages in glomerulonephritis in the rat. O2- generation, MHC class II expression, and eicosanoid synthesis. Am J Pathol 1989; 134: 431-437.
37. Boyce NW, Tipping PG, Holdsworth SR. Glomerular macrophages produce reactive oxygen species in experimental glomerulonephritis. Kidney Int 1989; 35: 778-782.
38. Matsumoto K. Production of interleukin-1 by glomerular macrophages in nephrotoxic serum nephritis. Am J Nephrol 1990; 10: 502-506.
39. Timoshanko JR, Kitching AR, Iwakura Y et al. Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor I to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis. Am J Pathol 2004; 164: 1967-1977.
40. Tipping PG, Leong TW, Holdsworth SR. Tumor necrosis factor production by glomerular macrophages in anti-glomerular basement membrane glomerulonephritis in rabbits. Lab Invest 1991; 65: 272-279.
41. Kluth DC, Erwig LP, Pearce WP et al. Gene transfer into inflamed glomeruli using macrophages transfected with adenovirus. Gene Ther 2000; 7: 263-270.
42. Kluth DC, Ainslie CV, Pearce WP et al. Macrophages transfected with adenovirus to express IL-4 reduce inflammation in experimental glomerulonephritis. J Immunol 2001; 166: 4728-4736.
43. Vielhauer V, Mayadas TN. Functions of TNF and its receptors in renal disease: distinct roles in inflammatory tissue injury and immune regulation. Semin Nephrol 2007; 27: 286-308.
44. Aringer M, Smolen JS. The role of tumor necrosis factor-alpha in systemic lupus erythematosus. Arthritis Res Ther 2008; 10: 202.
45. Asgeirsdottir SA, van Solingen C, Kurniati NF et al. MicroRNA-126 contributes to renal microvascular heterogeneity of VCAM-1 protein expression in acute inflammation. Am J Physiol Renal Physiol 2012; 302: F1630-F1639.
46. Neumann B, Machleidt T, Lifka A et al. Crucial role of 55-kilodalton TNF receptor in TNF-induced adhesion molecule expression and leukocyte organ infiltration. J Immunol 1996; 156: 1587-1593.
47. Vielhauer V, Anders HJ, Mack M et al. Obstructive nephropathy in the mouse: progressive fibrosis correlates with tubulointerstitial chemokine expression and accumulation of CC chemokine receptor 2- and 5-positive leukocytes. J Am Soc Nephrol 2001; 12: 1173-1187.
48. Vielhauer V, Allam R, Lindenmeyer MT et al. Efficient renal recruitment of macrophages and T cells in mice lacking the duffy antigen/receptor for chemokines. Am J Pathol 2009; 175: 119-131.
49. Vielhauer V, Anders HJ, Pérez de Lema G et al. Phenotyping renal leukocyte subsets by four-color flow cytometry: characterization of chemokine receptor expression. Nephron Exp Nephrol 2003; 93: e63-e71.