Trehangelins A, B and C, novel photo-oxidative hemolysis inhibitors produced by an endophytic actinomycete, Polymorphospora rubra K07-0510

Journal of Antibiotics

Volumn 66, Issue 6, 2013, Pages 311-317

  Nakashima, Takuji ^a   Okuyama, Ryuki ^a   Kamiya, Yoshiyuki ^a   Matsumoto, Atsuko ^a   Iwatsuki, Masato ^a   Inahashi, Yuki ^a   Yamaji, Kenzaburo ^a   Takahashi, Yoko ^a   Omura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

chemical screening; endophytic actinomycete; hemolysis inhibitor; Polymorphospora rubra; trehangelins

Indexed keywords

ASCORBIC ACID; HEMATOLOGIC AGENT; PHEOPHORBIDE; RNA 16S; TREHANGELINS A; TREHANGELINS B; TREHANGELINS C; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ARTICLE; BACTERIAL STRAIN; BIOLOGICAL ACTIVITY; COLUMN CHROMATOGRAPHY; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ERYTHROCYTE; GENE SEQUENCE; HEMOLYSIS; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOTOOXIDATION; PHYSICAL CHEMISTRY; POLYMORPHOSPORA RUBRA; PRIORITY JOURNAL; SOLVENT EXTRACTION; STEREOCHEMISTRY;

ACTINOBACTERIA; BIOLOGICAL PRODUCTS; CELL SURVIVAL; CHLOROPHYLL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPHYTES; ERYTHROCYTES; HEK293 CELLS; HEMOLYSIS; HT29 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR CONFORMATION; ORCHIDACEAE; OXIDATIVE STRESS; PHYSICOCHEMICAL PROCESSES; PLANT ROOTS; RADIATION-PROTECTIVE AGENTS; RADIATION-SENSITIZING AGENTS; TREHALOSE;

EID: 84879641548     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2013.17     Document Type: Article

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