Spoxazomicins A-C, novel antitrypanosomal alkaloids produced by an endophytic actinomycete, Streptosporangium oxazolinicum K07-0460 T

Journal of Antibiotics

Volumn 64, Issue 4, 2011, Pages 303-307

  Inahashi, Yuki ^a   Iwatsuki, Masato ^a   Ishiyama, Aki ^a   Namatame, Miyuki ^a   Nishihara Tsukashima, Aki ^a   Matsumoto, Atsuko ^a   Hirose, Tomoyasu ^a   Sunazuka, Toshiaki ^a   Yamada, Haruki ^a   Otoguro, Kazuhiko ^a   Takahashi, Yöko ^a   O'mura, Satoshi ^a   Shiomi, Kazuro ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

antitrypanosome; endophytic actinomycete; spoxazomicins; Streptosporangium oxazolinicum

Indexed keywords

ANTITRYPANOSOMAL AGENT; EFLORNITHINE; SPOXAZOMICIN A; SPOXAZOMICIN B; SPOXAZOMICIN C; SURAMIN; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS SUBTILIS; BACTEROIDES FRAGILIS; CANDIDA ALBICANS; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; ESCHERICHIA COLI; GEL CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PRIORITY JOURNAL; PROTEUS MIRABILIS; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS AUREUS; STREPTOSPORANGIUM OXAZOLINICUM KO7 0460; XANTHOMONAS CAMPESTRIS;

ACTINOBACTERIA; ALKALOIDS; CELL LINE; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; INHIBITORY CONCENTRATION 50; OXAZOLES; PHENOLS; SILICA GEL; THIAZOLES; TRYPANOCIDAL AGENTS;

STREPTOSPORANGIUM;

EID: 79955569186     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2011.16     Document Type: Article

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