Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold

Bioscience Reports

Volumn 33, Issue 3, 2013, Pages 513-527

  Gao, Bin ^a   Harvey, Peta J ^b   Craik, David J ^b   Ronjat, Michel ^c   De Waard, Michel ^c   Zhu, Shunyi ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

Author keywords

Cysteine stabilized helical and sheet motif; Functional dyad; Ryanodine receptor; Scorpion toxin; Solution structure; Voltage gated ion channel

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL STIMULATING AGENT; CYSTINE; INHIBITOR CYSTINE KNOT; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL TOXIN; PROTEIN INHIBITOR; RYANODINE RECEPTOR; SCORPION VENOM; SHAKER POTASSIUM CHANNEL; UNCLASSIFIED DRUG; CALCIUM; PEPTIDE;

AMIDATION; ARTICLE; BETA SHEET; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DROSOPHILA; ELECTROPHYSIOLOGY; EXON; INTRON; MAMMAL; MOLECULAR CLONING; MOLECULAR EVOLUTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN REFOLDING; PROTEIN SECONDARY STRUCTURE; SCORPION; XENOPUS;

BUTHIDA; BUTHIDAE; MAMMALIA; SCORPIONES;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALCIUM; CLONING, MOLECULAR; CYSTINE; EVOLUTION, MOLECULAR; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; PROTEIN REFOLDING; PROTEIN STRUCTURE, SECONDARY; SCORPION VENOMS; SCORPIONS; XENOPUS;

EID: 84879622348     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20130052     Document Type: Article

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