Cell signalling: Nutrient sensing lost in cancer

Nature

Volumn 498, Issue 7455, 2013, Pages 444-445

  Menon, Suchithra ^a   Manning, Brendan D ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CELL PROTEIN; GLUCOSE; GROWTH FACTOR; LIPID; PROTEIN; RAG PROTEIN; RAPAMYCIN; RHEB PROTEIN; UNCLASSIFIED DRUG;

CANCER; DISEASE INCIDENCE; GROWTH RATE; MUTATION; NUTRIENT AVAILABILITY; SENSORY SYSTEM DISORDER; SIGNALING;

ARTICLE; CANCER CELL; CANCER GENETICS; CANCER GROWTH; CELL COMMUNICATION; CELL FUNCTION; CELL GROWTH; CELL LINEAGE; CELL METABOLISM; CELL SURFACE; CELL SURVIVAL; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; GENE MUTATION; HUMAN; NUTRIENT AVAILABILITY; NUTRIENT SENSING; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TUBEROUS SCLEROSIS;

FOOD; HUMANS; MULTIPROTEIN COMPLEXES; NEOPLASMS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84879620962     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/498444a     Document Type: Article

References (9)

1. Bar-Peled, L. et al. Science 340, 1100-1106 (2013).
2. Laplante, M. & Sabatini, D. M. Cell 149, 274-293 (2012).
3. Dibble, C. C. & Manning, B. D. Nature Cell Biol. 15, 555-564 (2013).
4. Neklesa, T. K. & Davis, R. W. PLoS Genet. 5, e1000515 (2009).
5. Panchaud, N., Péli-Gulli, M. P. & De Virgilio, C. Sci. Signal. 6, ra42 (2013).
6. Menon, S. & Manning, B. D. Oncogene 27, S43-S51 (2008).
7. Li, J. et al. Cancer Res. 64, 6438 (2004).
8. Leprivier, G. et al. Cell 153, 1064-1079 (2013).
9. Shackelford, D. B. et al. Cancer Cell 23, 143-158 (2013).