Catecholamines and obesity: Effects of exercise and training

Sports Medicine

Volumn 43, Issue 7, 2013, Pages 591-600

  Zouhal, Hassane ^a   Lemoine Morel, Sophie ^a   Mathieu, Marie Eve ^b   Casazza, Gretchen A ^c,d   Jabbour, Georges ^a,b  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Medical Center Sports Medicine Program   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CATECHOLAMINE;

ADRENAL GLAND; ADRENERGIC SYSTEM; BLOOD; EXERCISE; HUMAN; METABOLISM; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

ADRENAL GLANDS; BIOLOGICAL MARKERS; CATECHOLAMINES; EXERCISE; HUMANS; OBESITY; SYMPATHETIC NERVOUS SYSTEM;

EID: 84879615528     PISSN: 01121642     EISSN: 11792035     Source Type: Journal    
DOI: 10.1007/s40279-013-0039-8     Document Type: Review

References (103)

1. Ogunbode AM, Ladipo M, Ajayi IO, et al. Obesity: an emerging disease. Niger J Clin Pract. 2011;14:390-4.
2. Bartness TJ, Shrestha YB, Vaughan CH, et al. Sensory and sympathetic nervous system control of white adipose tissue lipolysis. Mol Cell Endocrinol. 2010;318(1-2):34-43.
3. Sagnol M, Péquignot JM, Peyrin L. Rôle des catécholamines dans la mobilisation des substrats énergé tiques pendant l'exercice et la récupération. Science et Motricité. 1995;25:36-46.
4. Zouhal H, Jacob C, Delamarche P, et al. Catecholamines and the effects of exercise, training and gender. Sports Med. 2008;38(5):401-23.
5. Lafontan M. Kidney, adipose tissue, adipocytes - what's new? Nephrol Ther. 2011;7(2):69-79.
6. Lafontan M, Berlan M. Do regional differences in adipocyte biology provide new pathophysiological insights? Trends Pharmacol Sci. 2003;24(6):276-83.
7. Lafontan M, Langin D. Lipolysis and lipid mobilization in human adipose tissue. Prog Lipid Res. 2009;48(5):275-97.
8. Ravussin E, Lillioja S, Knowler WC, Christin L, et al. Reduced rate of energy expenditure as a risk factor for body-weight gain. N Engl J Med. 1988;318(8):467-72.
9. Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8.
10. Bougnères P, Stunff CL, Pecqueur C, et al. In vivo resistance of lipolysis to epinephrine. A new feature of childhood onset obesity. J Clin Invest. 1997;99(11):2568-73.
11. Mauriège P, Després JP, Prud'homme D, et al. Regional variation in adipose tissue lipolysis in lean and obese men. J Lipid Res. 1991;32:1625-33.
12. De Glisezinski I, Crampes F, Harant I, et al. Endurance training changes in lipolytic responsiveness of obese adipose tissue. Am J Physiol Endocrinol Metab. 1998;275:951-6.
13. Mauriège PD. Prud'Homme M, Marcotte M, et al. Regional differences in adipose tissue metabolism between sedentary and endurance-trained women. Am J Physiol. 1997;273(1):497-506.
14. Stich V, Marion-Latard F, Hejnova J, et al. Hypocaloric diet reduces exercise-induced alpha 2-adrenergic antilipolytic effect and alpha 2-adrenergic receptor mRNA levels in adipose tissue of obese women. J Clin Endocrinol Metab. 2002;87(3):1274-81.
15. Stich V, de Glisezinski I, Galitzky J, et al. Endurance training increases the beta-adrenergic lipolytic response in subcutaneous adipose tissue in obese subjects. Int J Obes Relat Metab Disord. 1999;23(4):374-81.
16. Troisi RJ, Weiss ST, Parker DR, et al. Relation of obesity and diet to sympathetic nervous system activity. Hypertension. 1991;17:669-77.
17. Jones PP, Davy KP, Alexander S, et al. Age-related increase in muscle sympathetic nerve activity is associated with abdominal adiposity. Am J Physiol. 1997;272:976-80.
18. Del Rio G. Adrenomedullary function and its regulation in obesity. Int J Obes Relat Metab Disord. 2000;24(S2):S89-91.
19. Tentolouris N, Liatis S, Katsilambros N. Sympathetic system activity in obesity and metabolic syndrome. Ann NY Acad Sci. 2006;1083:129-52.
20. Flaa A, Sandvik L, Kjeldsen SE. Does sympathoadrenal activity predict changes in body fat? An 18-y follow-up study. Am J Clin Nutr. 2008;87:1596-601.
21. Vettor R, Macor C, Rossi E, et al. Impaired counterregulatory hormonal and metabolic response to exhaustive exercise in obese subjects. Acta Diabetol. 1997;34(2):61-6.
22. Salvadori A, Fanari P, Palmulli P. Kinetics of catecholamines and potassium, and heart rate during exercise testing in obese subjects. Heart rate regulation in obesity during exercise. Eur J Nutr. 2003;42:181-7.
23. Zouhal H, Jabbour G, Youssef H, et al. Obesity and catecholamine responses to maximal exercise in adolescent girls. Eur J Appl Physiol. 2010;110(2):247-54.
24. Jabbour G, Lemoine-Morel S, Casazza GA, et al. Catecholamine response to exercise in obese, overweight, and lean adolescent boys. Med Sci Sports Exerc. 2011;43(3):408-15.
25. De Glisezinski I, Moro C, Pillard F, et al. Aerobic training improves exercise-induced lipolysis in SCAT and lipid utilization in overweight men. Am J Physiol Endocrinol Metab. 2003;285(5):984-90.
26. Després JP, Bouchard C, Savard R, et al. The effect of 20-week endurance training program on adipose tissue morphology and lipolysis in men and women. Metabolism. 1984;33:235-9.
27. Crampes F, Marion-Latard F, Zakaroff-Girard A, et al. Effects of a longitudinal training program on responses to exercise in overweight men. Obes Res. 2003;11:247-56.
28. Lönnqvist F, Thome A, Nilsell K, et al. A pathogenic role of visceral fat beta 3-adrenoceptors in obesity. J Clin Invest. 1995;95(3):1109-16.
29. Barbe P, Millet L, Galitzky J, et al. In situ assessment of the role of the beta-1,2,3-adrenoceptors in the control of lipolysis and nutritive blood flow in human subcutaneous adipose tissue. Br J Pharmacol. 1996;117:907-13.
30. Rosenbaum M, Malbon CC, Hirsch J, et al. Lack of beta-3-adrenergic effect on lipolysis in human subcutaneous adipose tissue. J Clin Endocrinol Metab. 1993;77(2):352-5.
31. Berlan M, Lafontan M. Evidence that epinephrine acts preferentially as an antilipolytic agent in abdominal human subcutaneous fat cells: assessment by analysis of beta- and alpha2-adrenoceptor properties. Eur J Clin Invest. 1985;15:341-6.
32. Mauriège P, Galitzky J, Berlan M, et al. Heterogeneous distribution of beta and alpha-2-adrenoceptor binding sites in human fat cells from various fat deposits: functional consequences. Eur J Clin Invest. 1987;17:156-65.
33. Horowitz JF. Fatty acid mobilization from adipose tissue during exercise. Trends Endocrinol Metab. 2003;14(8):386-92.
34. Bray GA. Reciprocal relation of food intake and sympathetic activity: experimental observations and clinical implications. Int J Obes Relat Metab Disord. 2000;2:8-17.
35. Snitker S, Macdonald I, Ravussin E, et al. The sympathetic nervous system and obesity: role in aetiology and treatment. Obes Rev. 2000;1(1):5-15.
36. Toth MJ, Poehlman ET. Sympathetic nervous system activity and resting metabolic rate in vegetarians. Metabolism. 1994;43(5):621-5.
37. Schwartz RS, Jaeger LF, Silberstein S, et al. Sympathetic nervous system activity and the thermic effect of feeding in man. Int J Obes. 1987;11(2):141-9.
38. Matsumoto T, Miyawaki C, Ue H, Kanda T, et al. Comparison of thermogenic sympathetic response to food intake between obese and non-obese young women. Obes Res. 2001;9(2):78-85.
39. Nagaia N, Sakanec N, Hamadaa T, Kimuraa S, Moritania T. The effect of a high-carbohydrate meal on postprandial thermogenesis and sympathetic nervous system activity in boys with a recent onset of obesity. Metab Clin Exp. 2005;54:430-8.
40. Vallbo AB, Hagbarth KE, Torebjork HE, Wallin BG. Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. Physiol Rev. 1979;59:919-57.
41. Grassi G, Seravalle G, Quarti-Trevano F, et al. Reinforcement of the adrenergic overdrive in the metabolic syndrome complicated by obstructive sleep apnea. J Hypertens. 2010;28(6):1313-20.
42. Lambert E, Straznicky N, Schlaich M, et al. Differing pattern of sympathoexcitation in normal-weight and obesity-related hypertension. Hypertension. 2007;50(5):862-8.
43. Lambert E, Dawood T, Straznicky N, et al. Association between the sympathetic firing pattern and anxiety level in patients with the metabolic syndrome and elevated blood pressure. J Hypertens. 2010;28(3):543-50.
44. Grassi G, Dell'Oro R, Facchini A, Quarti TF, Bolla GB, Mancia G. Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives. J Hypertens. 2004;22:2363-9.
45. Alvarez GE, Beske SD, Ballard TP, Davy KP. Sympathetic neural activation in visceral obesity. Circulation. 2002;106:2533-6.
46. Alvarez GE, Ballard TP, Beske SD, Davy KP. Subcutaneous obesity is not associated with sympathetic neural activation. Am J Physiol Heart Circ Physiol. 2004;287:414-8.
47. Straznicky NE, Lambert EA, Lambert GW, et al. Effects of dietary weight loss on sympathetic activity and cardiac risk factors associated with the metabolic syndrome. J Clin Endocrinol Metab. 2005;90:5998-6005.
48. Straznicky NE, Lambert GW, McGrane MT, et al. Weight loss may reverse blunted sympathetic neural responsiveness to glucose ingestion in obese subjects with metabolic syndrome. Diabetes. 2009;58:1126-32.
49. Straznicky NE, Grima MT, Eikelis N, et al. The effects of weight loss versus weight loss maintenance on sympathetic nervous system activity and metabolic syndrome components. J Clin Endocrinol Metab. 2011;96:503-8.
50. Straznicky NE, Eikelis N, Nestel PJ, et al. Baseline sympathetic nervous system activity predicts dietary weight loss in obese metabolic syndrome subjects. J Clin Endocrinol Metab. 2012;97(2):605-13.
51. Vaz M, Jennings G, Turner A, Cox H, Lambert G, Esler M. Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects. Circulation. 1997;96:3423-9.
52. Spraul M, Ravussin E, Fontvielle AM. Reduced sympathetic nervous activity: a potential mechanism predisposing to body weight gain. J Clin Invest. 1993;92:1730-5.
53. Tataranni PA, Young JB, Bogardus C, et al. A low sympathoadrenal activity is associated with body weight gain and development of central adiposity in Pimas Indian men. Obes Res. 1997;5:341-7.
54. Eikelis N, Esler M. The neurobiology of human obesity. Exp Physiol. 2005;90(5):673-82.
55. Ahlquist RP. A study of the adrenotropic receptors. Am J Physiol. 1948;153:586-600.
56. Jocken JW, Goossens GH, van Hees AM, et al. Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men. Diabetologia. 2008;51:320-7.
57. Östman J, Arner P, Engfeldt P, et al. Regional differences in the control of lipolysis in human adipose tissue. Metabolism. 1979;28:1198-205.
58. Kather H, Wieland E, Fisher B, et al. Adrenergic regulation of lipolysis in abdominal adipocytes of obese subjects during caloric restriction: reversal of catecholamine action caused by relief of endogenous inhibition. Eur J Clin Invest. 1985;15:30-7.
59. Leibel RF, Berry EM, Hirsh J. Metabolic and hemodynamic responses to endogenous and exogenous catecholamines in formerly obese subjects. Am J Physiol. 1991;260:785-91.
60. Dax E, Partilla JS, Gregerman RJ. Increased sensitivity to epinephrine stimulated lipolysis during starvation: tighter coupling of the adenylate cyclise complex. Biochem Biophys Res Commun. 1981;101:1186-92.
61. Jensen MD, Haymond MW, Gerich JE, et al. Lipolysis during fasting. Decreased suppression by insulin and increased stimulation by epinephrine. J Clin Invest. 1987;79(1):207-13.
62. Oppert JM, Nadeau A, Tremblay A, et al. Negative energy balance with exercise in identical twins: plasma glucose and insulin responses. Am J Physiol. 1997;272:248-54.
63. Weinstock RS, Dai H, Wadden TA. Diet and exercise in the treatment of obesity: effects of 3 interventions on insulin resistance. Arch Intern Med. 1998;158:2477-83.
64. Harant I, Marion-Latard F, Crampes F, et al. Effect of a long-duration physical exercise on fat cell lipolytic responsiveness to adrenergic agents and insulin in obese men. Int J Obes. 2002;26:1373-8.
65. Hardman AE, Jones PRM, Norgan NG, et al. Brisk walking improves endurance fitness without changing body fatness in previously sedentary women. Eur J Appl Physiol Occup Physiol. 1992;65:354-9.
66. Borsheim E, Lonnroth P, Knardahl S, et al. No difference in lipolytic response to beta- adrenoreceptors stimulation in situ but a delayed increase in adipose tissue blood flow in moderate obese compared with lean men in the post-exercise period. Metabolism. 2000;49:579-87.
67. Stich V, De Glisezinski I, Crampes F, et al. Activation of alpha(2)-adrenergic receptors impairs exercise-induced lipolysis in SCAT of obese subjects. Am J Physiol Regul Integr Comp Physiol. 2000;279(2):499-504.
68. Richterova B, Stich V, Moro C, et al. Effect of endurance training on adrenergic control of lipolysis in adipose tissue of obese women. J Clin Endocrinol Metab. 2004;89(3):1325-31.
69. Pillard F, Moro C, Harant I, et al. Lipid oxidation according to intensity and exercise duration in overweight men and women. Obesity. 2007;15:2256-62.
70. Davis SN, Biaggioni I. Autonomic contribution to blood pressure and metabolism in obesity. Hypertension. 2007;49(1):c27-33.
71. Moro C, Crampes F, Sengenes C, et al. Atrial natriuretic peptide contributes to physiological control of lipid mobilization in humans. FASEB J. 2004;18(7):908-10.
72. Stich V, de Glisezinski I, Crampes F, et al. Activation of antilipolytic α2-adrenergic receptors by epinephrine during exercise in human adipose tissue. Am J Physiol Regul Integr Comp Physiol. 1999;277:1076-83.
73. Nicklas BJ, Rogus EM, Andrew P. Goldberg. Exercise blunts declines in lipolysis and fat oxidation after dietary-induced weight loss in obese older women. Am J Physiol. 1997;273:l49-55.
74. Polak J, Moro C, Klimcakova E, et al. Dynamic strength training improves insulin sensitivity and functional balance between adrenergic alpha 2A and beta pathways in subcutaneous adipose tissue of obese subjects. Diabetologia. 2005;48(12):2631-40.
75. Florkowski CM, Collier GR, Zimmet PZ, et al. Low-dose growth hormone replacement lowers plasma leptin and fat stores without affecting body mass index in adults with growth hormone deficiency. Clin Endorcinol (Oxf). 1996;45:769-73.
76. Hansen BC, Jen KL, Pek SB, et al. Rapid oscillations on plasma insulin, glucagon, and glucose in obese and normal weight humans. J Clin Endocrinol Metab. 1982;54(4):785-92.
77. Annerbrink K, Westberg L, Nilsson S, Rosmond R, Holm G, Eriksson E. Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men. Metabolism. 2008;57(5):708-11.
78. Lundberg U. Stress hormones in health and illness: the roles of work and gender. Psychoneuroendocrinology. 2005;30(10):1017-21.
79. Chaput JP, Tremblay A. Acute effects of knowledge-based work on feeding behavior and energy intake. Physiol Behav. 2007;90:66-72.
80. Chaput JP, Drapeau V, Poirier P, et al. Glycemic instability and spontaneous energy intake: association with knowledge-based work. Psychosom Med. 2008;70:797-804.
81. McCann BS, Warnick GR, Knopp RH. Changes in plasma lipids and dietary intake accompanying shifts in perceived workload and stress. Psychosom Med. 1990;52:97-108.
82. Lalluka T, Sarlio-Lähteenkorva S, Kaila-Kangas L, et al. Working conditions and weight gain: a 28-year follow-up study of industrial employees. Eur J Epidemiol. 2008;23:303-10.
83. Rutters F, Nieuwenhuizen AG, Lemmens SG, et al. Acute stress-related changes in eating in the absence of hunger. Obesity. 2009;17:72-7.
84. Sluiter JK, Frings-dresen MH, van der Beek AJ, et al. Neuroendocrine reactivity and recovery from work with different physical and mental demands. Scand J Work Environ Health. 2000;26(4):306-16.
85. Yale JF, Leiter LA, Marliss EB. Metabolic responses to intense exercise in lean and obese subjects. J Clin Endocrinol Metab. 1989;68:438-45.
86. Gustafson AB, Farrell PA, Kalkhoff RK. Impaired plasma catecholamine response to submaximal treadmill exercise in obese women. Metabolism. 1990;39:410-7.
87. Pullinen T, Mero A, Huttunen P, et al. Resistance exercise-induced hormonal responses in men, women, and pubescent boys. Med Sci Sports Exerc. 2002;34(5):806-13.
88. Botcazou M, Zouhal H, Jacob C. Effect of training and detraining on catecholamine responses to sprint exercise in adolescent girls. Eur J Appl Physiol. 2006;97:68-75.
89. Eliakim A, Nemet D, Zaldivar F, et al. Reduced exercise-associated response of the GH-IGF-I axis and catecholamines in obese children and adolescents. J Appl Physiol. 2006;100:1630-7.
90. Livett G, Marley P. Noncholinergic control of adrenal catecholamine secretion. J Anat. 1993;183:277-89.
91. Mannelli M, Lanzilotti R, Pupilli C, et al. Adrenal medulla secretion in Cushing's syndrome. J Clin Endocrinol Metab. 1994;78(6):1331-5.
92. Montain SJ, Hopper MK, Coggan AR, et al. Exercise metabolism at different time intervals after a meal. J Appl Physiol. 1991;70:882-8.
93. Kindermann W, Schnabel A, Schmitt WM, et al. Catecholamines, growth hormone, cortisol, insulin, and sex hormones in anaerobic and aerobic exercise. Eur J Appl Physiol. 1982;49:389-99.
94. Navëri H, Kuoppasalmi K, Härkönen M. Plasma glucagons and catecholamines during exhaustive short-term exercise. Eur J Appl Physiol. 1985;53:308-11.
95. Kjaer M, Sécher NH, Galbo H. Physical stress and catecholamine release. Baillieres Clin Endocrinol Metab. 1987;I(2):279-98.
96. Ben Abderrahmane A, Prioux J, Mrizek I, et al. Recovery (passive vs. active) during interval training and plasma catecholamine responses. Int J Sports Med 2013 [Epub ahead of print].
97. Zouhal H, Rannou F, Gratas-Delamarche A, et al. Adrenal medulla responsiveness to the sympathetic nervous activity in sprinters and untrained subjects during a supramaximal exercise. Int J Sports Med. 1998;19:172-6.
98. Dorien PC, Van Aggel-Leijssen, Saris HM, et al. Effect of exercise training at different intensities on fat metabolism of obese men. J Appl Physiol. 2002;92:1300-9.
99. Harrison MH. Effects on thermal stress and exercise on blood volume in humans. Physiol Rev. 1985;65(1):149-209.
100. Berthoin S, Pelayo P, Baquet G, et al. Effets des variations du volume plasmatique sur les concentrations de lactate et leur cinétique de récupération après des exercices maximaux et supramaximaux. Sci Sports. 2000;15:31-9.
101. Berthoin S, Allender H, Baquet G, et al. Plasma lactate and plasma volume recovery in adults and children following high-intensity exercises. Acta Paediatr. 2003;3:283-90.
102. Zouhal H, Vincent S, Moussa E, et al. Influence of training status on plasma volume variations and plasma lactate concentrations in response to supramaximal exercise. Biol Sport. 2007;24:341-58.
103. Ben Abderrahman A, Prioux J, Chamari K, et al. Running interval training and estimated plasma variation. Int J Sports Physiol Perf 2013 (in press).