-
1
-
-
0028793257
-
Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function
-
Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P. 1995. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961-973.
-
(1995)
Neuron
, vol.15
, pp. 961-973
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Bonfoco, E.3
Zhivotovsky, B.4
Orrenius, S.5
Lipton, S.A.6
Nicotera, P.7
-
2
-
-
0023572285
-
Glial glutamate dehydrogenase: ultrastructural localization and regional distribution in relation to the mitochondrial enzyme, cytochrome oxidase
-
Aoki C, Milner T, Berger S, Sheu K, Blass J, Pickel V. 1987. Glial glutamate dehydrogenase: ultrastructural localization and regional distribution in relation to the mitochondrial enzyme, cytochrome oxidase. JNeurosci Res 18:305-318.
-
(1987)
JNeurosci Res
, vol.18
, pp. 305-318
-
-
Aoki, C.1
Milner, T.2
Berger, S.3
Sheu, K.4
Blass, J.5
Pickel, V.6
-
3
-
-
1842558602
-
Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
-
Arundine M, Tymianski M. 2004. Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell Mol Life Sci 61:657-668.
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 657-668
-
-
Arundine, M.1
Tymianski, M.2
-
4
-
-
56849124017
-
Neurological aspects of hyperinsulinism-hyperammonaemia syndrome
-
Bahi-Buisson N, Roze E, Dionisi C, Escande F, Valayannopoulos V, Feillet F, Heinrichs C, Chadefaux-Vekemans B, Dan B, de Lonlay P. 2008. Neurological aspects of hyperinsulinism-hyperammonaemia syndrome. Dev Med Child Neurol 50:945-949.
-
(2008)
Dev Med Child Neurol
, vol.50
, pp. 945-949
-
-
Bahi-Buisson, N.1
Roze, E.2
Dionisi, C.3
Escande, F.4
Valayannopoulos, V.5
Feillet, F.6
Heinrichs, C.7
Chadefaux-Vekemans, B.8
Dan, B.9
de Lonlay, P.10
-
5
-
-
70449435661
-
Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability
-
Bao X, Pal R, Hascup KN, Wang Y, Wang WT, Xu W, Hui D, Agbas A, Wang X, Michaelis ML, Choi IY, Belousov AB, Gerhardt GA, Michaelis EK. 2009. Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. J Neurosci 29:13929-13944.
-
(2009)
J Neurosci
, vol.29
, pp. 13929-13944
-
-
Bao, X.1
Pal, R.2
Hascup, K.N.3
Wang, Y.4
Wang, W.T.5
Xu, W.6
Hui, D.7
Agbas, A.8
Wang, X.9
Michaelis, M.L.10
Choi, I.Y.11
Belousov, A.B.12
Gerhardt, G.A.13
Michaelis, E.K.14
-
6
-
-
0344837307
-
Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation
-
Banerjee S, Schmidt T, Fang J, Stanley CA, Smith TJ. 2003. Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation. Biochemistry 42:3446-3456.
-
(2003)
Biochemistry
, vol.42
, pp. 3446-3456
-
-
Banerjee, S.1
Schmidt, T.2
Fang, J.3
Stanley, C.A.4
Smith, T.J.5
-
7
-
-
0031466522
-
Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy
-
Bartha R, Williamson PC, Drost DJ, Malla A, Carr TJ, Cortese L, Canaran G, Rylett RJ, Neufeld RW. 1997. Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy. Arch Gen Psychiatry 54:959-965.
-
(1997)
Arch Gen Psychiatry
, vol.54
, pp. 959-965
-
-
Bartha, R.1
Williamson, P.C.2
Drost, D.J.3
Malla, A.4
Carr, T.J.5
Cortese, L.6
Canaran, G.7
Rylett, R.J.8
Neufeld, R.W.9
-
8
-
-
0028224736
-
Regulation of enzymatic activity by active site fatty acylation. A new role for long chain fatty acid acylation of proteins
-
Berthiaume L, Deichaite I, Peseckis S, Resh MD. 1994. Regulation of enzymatic activity by active site fatty acylation. A new role for long chain fatty acid acylation of proteins. J Biol Chem 4269:6498-6505.
-
(1994)
J Biol Chem
, vol.4269
, pp. 6498-6505
-
-
Berthiaume, L.1
Deichaite, I.2
Peseckis, S.3
Resh, M.D.4
-
9
-
-
77957775885
-
Estrogen modification of human glutamate dehydrogenases is linked to enzyme activation state
-
Borompokas N, Papachatzaki MM, Kanavouras K, Mastorodemos V, Zaganas I, Spanaki C, Plaitakis A. 2010. Estrogen modification of human glutamate dehydrogenases is linked to enzyme activation state. JBiol Chem 285:31380-31387.
-
(2010)
JBiol Chem
, vol.285
, pp. 31380-31387
-
-
Borompokas, N.1
Papachatzaki, M.M.2
Kanavouras, K.3
Mastorodemos, V.4
Zaganas, I.5
Spanaki, C.6
Plaitakis, A.7
-
10
-
-
0038012557
-
Glutamine synthetase and glutamate dehydrogenase in the prefrontal cortex of patients with schizophrenia
-
Burbaeva GS, Boksha IS, Turishcheva MS, Vorobyeva EA, Savushkina OK, Tereshkina EB. 2003. Glutamine synthetase and glutamate dehydrogenase in the prefrontal cortex of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 27:675-680.
-
(2003)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.27
, pp. 675-680
-
-
Burbaeva, G.S.1
Boksha, I.S.2
Turishcheva, M.S.3
Vorobyeva, E.A.4
Savushkina, O.K.5
Tereshkina, E.B.6
-
11
-
-
34447640017
-
Systemic neurochemical alterations in schizophrenic brain: glutamate metabolism in focus
-
Burbaeva GS, Boksha IS, Tereshkina EB, Savushkina OK, Starodubtseva LI, Turishcheva MS, Mukaetova-Ladinska E. 2007. Systemic neurochemical alterations in schizophrenic brain: glutamate metabolism in focus. Neurochem Res 32:1434-1444.
-
(2007)
Neurochem Res
, vol.32
, pp. 1434-1444
-
-
Burbaeva, G.S.1
Boksha, I.S.2
Tereshkina, E.B.3
Savushkina, O.K.4
Starodubtseva, L.I.5
Turishcheva, M.S.6
Mukaetova-Ladinska, E.7
-
12
-
-
6944242766
-
Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux
-
Burki F, Kaessmann H. 2004. Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux. Nat Genet 36:1061-1063.
-
(2004)
Nat Genet
, vol.36
, pp. 1061-1063
-
-
Burki, F.1
Kaessmann, H.2
-
13
-
-
33646152528
-
A dopaminergic deficit hypothesis of schizophrenia: the path to discovery
-
Carlsson A, Carlsson ML. 2006. A dopaminergic deficit hypothesis of schizophrenia: the path to discovery. Dialogues Clin Neurosci 8:137-142.
-
(2006)
Dialogues Clin Neurosci
, vol.8
, pp. 137-142
-
-
Carlsson, A.1
Carlsson, M.L.2
-
14
-
-
0030955354
-
Late memory-related genes in the hippocampus revealed by RNA fingerprinting
-
Cavallaro S, Meiri N, Yi CL, Musco S, Ma W, Goldberg J, Alkon DL. 1997. Late memory-related genes in the hippocampus revealed by RNA fingerprinting. Proc Natl Acad Sci U S A 94:9669-9673.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 9669-9673
-
-
Cavallaro, S.1
Meiri, N.2
Yi, C.L.3
Musco, S.4
Ma, W.5
Goldberg, J.6
Alkon, D.L.7
-
15
-
-
0018149605
-
Methodological aspects of the histochemical localization and activity of some cerebellar dehydrogenases
-
Contestabile A, Andersen H. 1978. Methodological aspects of the histochemical localization and activity of some cerebellar dehydrogenases. Histochemistry 56:117-132.
-
(1978)
Histochemistry
, vol.56
, pp. 117-132
-
-
Contestabile, A.1
Andersen, H.2
-
16
-
-
0025058979
-
The inhibition of glutamate dehydrogenase by some antipsychotic drugs
-
Couée I, Tipton KF. 1990. The inhibition of glutamate dehydrogenase by some antipsychotic drugs. Biochem Pharmacol 39:827-832.
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 827-832
-
-
Couée, I.1
Tipton, K.F.2
-
17
-
-
0025326250
-
Activation of glutamate dehydrogenase by leucine and its nonmetabolizable analogue in rat brain synaptosomes
-
Erecinska M, Nelson D. 1990. Activation of glutamate dehydrogenase by leucine and its nonmetabolizable analogue in rat brain synaptosomes. J Neurochem 54:1335-1343.
-
(1990)
J Neurochem
, vol.54
, pp. 1335-1343
-
-
Erecinska, M.1
Nelson, D.2
-
18
-
-
0019809137
-
Regulation of glutamate dehydrogenase by palmitoyl-coenzyme A
-
Fahien LA, Kiomtek E. 1981. Regulation of glutamate dehydrogenase by palmitoyl-coenzyme A. Arch Biochem Biophys 212:247-253.
-
(1981)
Arch Biochem Biophys
, vol.212
, pp. 247-253
-
-
Fahien, L.A.1
Kiomtek, E.2
-
19
-
-
80053426332
-
The complex mechanism of glutamate dehydrogenase in insulin secretion
-
Fahien LA, Macdonald MJ. 2011. The complex mechanism of glutamate dehydrogenase in insulin secretion. Diabetes 60:2450-2454.
-
(2011)
Diabetes
, vol.60
, pp. 2450-2454
-
-
Fahien, L.A.1
Macdonald, M.J.2
-
20
-
-
0014751081
-
Effects of chlorpromazine on glutamate dehydrogenase
-
Fahien LA, Shemisa O. 1970. Effects of chlorpromazine on glutamate dehydrogenase. Mol Pharmacol 6:156-163.
-
(1970)
Mol Pharmacol
, vol.6
, pp. 156-163
-
-
Fahien, L.A.1
Shemisa, O.2
-
21
-
-
0036534464
-
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations
-
Fang J, Hsu BY, MacMullen CM, Poncz M, Smith TJ, Stanley CA. 2002Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. Biochem J 363:81-87.
-
(2002)
Biochem J
, vol.363
, pp. 81-87
-
-
Fang, J.1
Hsu, B.Y.2
MacMullen, C.M.3
Poncz, M.4
Smith, T.J.5
Stanley, C.A.6
-
22
-
-
0036307527
-
Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients
-
Gluck MR, Thomas RG, Davis KL, Haroutunian V. 2002. Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. Am J Psychiatry 159:1165-1173.
-
(2002)
Am J Psychiatry
, vol.159
, pp. 1165-1173
-
-
Gluck, M.R.1
Thomas, R.G.2
Davis, K.L.3
Haroutunian, V.4
-
23
-
-
33748316536
-
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
-
Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, Wolberger C, Prolla TA, Weindruch R, Alt FW, Guarente L. 2006. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 126:941-954.
-
(2006)
Cell
, vol.126
, pp. 941-954
-
-
Haigis, M.C.1
Mostoslavsky, R.2
Haigis, K.M.3
Fahie, K.4
Christodoulou, D.C.5
Murphy, A.J.6
Valenzuela, D.M.7
Yancopoulos, G.D.8
Karow, M.9
Blander, G.10
Wolberger, C.11
Prolla, T.A.12
Weindruch, R.13
Alt, F.W.14
Guarente, L.15
-
24
-
-
0029051676
-
The phencyclidine-glutamate model of schizophrenia
-
Halberstadt AL. 1995. The phencyclidine-glutamate model of schizophrenia. Clin Neuropharmacol 18:237-249.
-
(1995)
Clin Neuropharmacol
, vol.18
, pp. 237-249
-
-
Halberstadt, A.L.1
-
25
-
-
26844558198
-
Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients
-
Hashimoto K, Engberg G, Shimizu E, Nordin C, Lindström LH, Iyo M. 2005. Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients. BMC Psychiatry 5:6.
-
(2005)
BMC Psychiatry
, vol.5
, pp. 6
-
-
Hashimoto, K.1
Engberg, G.2
Shimizu, E.3
Nordin, C.4
Lindström, L.H.5
Iyo, M.6
-
26
-
-
0028325907
-
Effect of polyamines on glutamate dehydrogenase within permeabilized kidney-cortex mitochondria and isolated renal tubules of rabbit
-
Jarzyna R, Lietz T, Brya J. 1994. Effect of polyamines on glutamate dehydrogenase within permeabilized kidney-cortex mitochondria and isolated renal tubules of rabbit. Biochem Pharmacol 47:1387-1393.
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 1387-1393
-
-
Jarzyna, R.1
Lietz, T.2
Brya, J.3
-
27
-
-
64349103857
-
Mutations in human GLUD2 glutamate dehydrogenase affecting basal activity and regulation
-
Kanavouras K, Borompokas N, Latsoudis H, Stagourakis A, Zaganas I, Plaitakis A. 2009. Mutations in human GLUD2 glutamate dehydrogenase affecting basal activity and regulation. J Neurochem 109( Suppl 1):167-173.
-
(2009)
J Neurochem
, vol.109
, Issue.SUPPL 1
, pp. 167-173
-
-
Kanavouras, K.1
Borompokas, N.2
Latsoudis, H.3
Stagourakis, A.4
Zaganas, I.5
Plaitakis, A.6
-
28
-
-
0027905017
-
Modulation of neuronal migration by NMDA receptors
-
Komuro H, Rakic P. 1993. Modulation of neuronal migration by NMDA receptors. Science 260:95-97.
-
(1993)
Science
, vol.260
, pp. 95-97
-
-
Komuro, H.1
Rakic, P.2
-
29
-
-
0033190699
-
NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders
-
Krystal JH, D'souza DC, Petrakis IL, Belger A, Berman RM, Charney DS, Abi-Saab W, Madonick S. 1999. NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders. Harv Rev Psychiatry 7:125-143.
-
(1999)
Harv Rev Psychiatry
, vol.7
, pp. 125-143
-
-
Krystal, J.H.1
D'souza, D.C.2
Petrakis, I.L.3
Belger, A.4
Berman, R.M.5
Charney, D.S.6
Abi-Saab, W.7
Madonick, S.8
-
30
-
-
0027934856
-
2+ and polyamines: a possible cause for its low in vivo activity
-
2+ and polyamines: a possible cause for its low in vivo activity. J Neurochem 63:751-757.
-
(1994)
J Neurochem
, vol.63
, pp. 751-757
-
-
Kuo, N.1
Michalik, M.2
Ereciňska, M.3
-
31
-
-
0036135109
-
Impaired brain GABA in focal dystonia
-
Levy LM, Hallett M. 2002. Impaired brain GABA in focal dystonia. Ann Neurol 51:93-101.
-
(2002)
Ann Neurol
, vol.51
, pp. 93-101
-
-
Levy, L.M.1
Hallett, M.2
-
32
-
-
77957760755
-
Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase
-
Li C, Chen P, Palladino A, Narayan S, Russell LK, Sayed S, Xiong G, Chen J, Stokes D, Butt YM, Jones PM, Collins HW, Cohen NA, Cohen AS, Nissim I, Smith TJ, Strauss AW, Matschinsky FM, Bennett MJ, Stanley CA. 2010. Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase. J Biol Chem 285:31806-31818.
-
(2010)
J Biol Chem
, vol.285
, pp. 31806-31818
-
-
Li, C.1
Chen, P.2
Palladino, A.3
Narayan, S.4
Russell, L.K.5
Sayed, S.6
Xiong, G.7
Chen, J.8
Stokes, D.9
Butt, Y.M.10
Jones, P.M.11
Collins, H.W.12
Cohen, N.A.13
Cohen, A.S.14
Nissim, I.15
Smith, T.J.16
Strauss, A.W.17
Matschinsky, F.M.18
Bennett, M.J.19
Stanley, C.A.20
more..
-
33
-
-
80052271742
-
The structure and allosteric regulation of glutamate dehydrogenase
-
Li M, Li C, Allen A, Stanley CA, Smith TJ. 2011. The structure and allosteric regulation of glutamate dehydrogenase. Neurochem Int 59:445-455.
-
(2011)
Neurochem Int
, vol.59
, pp. 445-455
-
-
Li, M.1
Li, C.2
Allen, A.3
Stanley, C.A.4
Smith, T.J.5
-
34
-
-
0020063951
-
Lack of effect on glutamate dehydrogenase activity after in vivo administration of pharmacological doses of haloperidol
-
Luengo de Borges E, Ryder E, Campos G. 1982. Lack of effect on glutamate dehydrogenase activity after in vivo administration of pharmacological doses of haloperidol. Biochem Pharmacol 31:1446-1448.
-
(1982)
Biochem Pharmacol
, vol.31
, pp. 1446-1448
-
-
Luengo de Borges, E.1
Ryder, E.2
Campos, G.3
-
35
-
-
0027390458
-
Quantitative synaptic alterations in the human neocortex during normal aging
-
Masliah E, Mallory M, Hansen L, DeTeresa R, Terry RD. 1993. Quantitative synaptic alterations in the human neocortex during normal aging. Neurology 43:192-197.
-
(1993)
Neurology
, vol.43
, pp. 192-197
-
-
Masliah, E.1
Mallory, M.2
Hansen, L.3
DeTeresa, R.4
Terry, R.D.5
-
36
-
-
0027302996
-
Glutamate: its role in learning, memory, and the aging brain
-
McEntee WJ, Crook TH. 1993. Glutamate: its role in learning, memory, and the aging brain. Psychopharmacology 111:391-401.
-
(1993)
Psychopharmacology
, vol.111
, pp. 391-401
-
-
McEntee, W.J.1
Crook, T.H.2
-
37
-
-
80052290024
-
Glutamate dehydrogenase in brain mitochondria: do lipid modifications and transient metabolon formation influence enzyme activity?
-
McKenna MC. 2011. Glutamate dehydrogenase in brain mitochondria: do lipid modifications and transient metabolon formation influence enzyme activity?Neurochem Int 59:525-533.
-
(2011)
Neurochem Int
, vol.59
, pp. 525-533
-
-
McKenna, M.C.1
-
38
-
-
0029972176
-
New insights into the compartmentation of glutamate and glutamine in cultured rat brain astrocytes
-
McKenna M, Tildon J, Stevenson J, Huang X. 1996. New insights into the compartmentation of glutamate and glutamine in cultured rat brain astrocytes. Dev Neurosci 18:380-390.
-
(1996)
Dev Neurosci
, vol.18
, pp. 380-390
-
-
McKenna, M.1
Tildon, J.2
Stevenson, J.3
Huang, X.4
-
39
-
-
0032473367
-
Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
-
Michaelis EK. 1998. Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging. Prog Neurobiol 54:369-415.
-
(1998)
Prog Neurobiol
, vol.54
, pp. 369-415
-
-
Michaelis, E.K.1
-
40
-
-
84864777670
-
Generalized dystonia in a patient with a novel mutation in the GLUD1 gene
-
doi: 10.1002/mds.25081.
-
Miyamoto R, Goto S, Sako W, Miyashiro A, Kim I, Escande F, Harada M, Morigaki R, Asanuma K, Mizobuchi Y, Nagahiro S, Izumi Y, Kaji R. 2012. Generalized dystonia in a patient with a novel mutation in the GLUD1 gene. Mov Disord doi: 10.1002/mds.25081.
-
(2012)
Mov Disord
-
-
Miyamoto, R.1
Goto, S.2
Sako, W.3
Miyashiro, A.4
Kim, I.5
Escande, F.6
Harada, M.7
Morigaki, R.8
Asanuma, K.9
Mizobuchi, Y.10
Nagahiro, S.11
Izumi, Y.12
Kaji, R.13
-
41
-
-
0347990591
-
Familial hyperinsulinemic hypoglycemia caused by a defect in the SCHAD enzyme of mitochondrial fatty acid oxidation
-
Molven A, Matre GE, Duran M, Wanders RJ, Rishaug U, Njlstad PR, Jellum E, Svik O. 2004. Familial hyperinsulinemic hypoglycemia caused by a defect in the SCHAD enzyme of mitochondrial fatty acid oxidation. Diabetes 53:221-227.
-
(2004)
Diabetes
, vol.53
, pp. 221-227
-
-
Molven, A.1
Matre, G.E.2
Duran, M.3
Wanders, R.J.4
Rishaug, U.5
Njlstad, P.R.6
Jellum, E.7
Svik, O.8
-
42
-
-
0030698871
-
Life and death of neurons in the aging brain
-
Morrison JH, Hof PR. 1997. Life and death of neurons in the aging brain. Science 278:412-419.
-
(1997)
Science
, vol.278
, pp. 412-419
-
-
Morrison, J.H.1
Hof, P.R.2
-
43
-
-
0024411518
-
Role of aspartate aminotransferase and mitochondrial dicarboxylate transport for release of endogenously and exogenously supplied neurotrasmitter in glutamatergic neurons
-
Palaiologos G, Hertz L, Schousboe A. 1989. Role of aspartate aminotransferase and mitochondrial dicarboxylate transport for release of endogenously and exogenously supplied neurotrasmitter in glutamatergic neurons. Neurochem Res 14:359-366.
-
(1989)
Neurochem Res
, vol.14
, pp. 359-366
-
-
Palaiologos, G.1
Hertz, L.2
Schousboe, A.3
-
44
-
-
0033565447
-
The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery
-
Peterson PE, Smith TJ. 1999. The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery. Structure 7:769-782.
-
(1999)
Structure
, vol.7
, pp. 769-782
-
-
Peterson, P.E.1
Smith, T.J.2
-
45
-
-
0020164840
-
The chymotrypsin-catalysed activation of bovine liver glutamate dehydrogenase
-
Place GA, Beynon RJ. 1982. The chymotrypsin-catalysed activation of bovine liver glutamate dehydrogenase. Biochem J 205:75-80.
-
(1982)
Biochem J
, vol.205
, pp. 75-80
-
-
Place, G.A.1
Beynon, R.J.2
-
46
-
-
0020322196
-
Abnormal glutamate metabolism in an adult onset degenerative neurological disorder
-
Plaitakis A, Berl S, Yahr MD. 1982. Abnormal glutamate metabolism in an adult onset degenerative neurological disorder. Science 216:193-196.
-
(1982)
Science
, vol.216
, pp. 193-196
-
-
Plaitakis, A.1
Berl, S.2
Yahr, M.D.3
-
47
-
-
0021340557
-
Neurological disorders associated with deficiency of glutamate dehydrogenase
-
Plaitakis A, Berl S, Yahr M. 1984. Neurological disorders associated with deficiency of glutamate dehydrogenase. Ann Neurol 15:144-153.
-
(1984)
Ann Neurol
, vol.15
, pp. 144-153
-
-
Plaitakis, A.1
Berl, S.2
Yahr, M.3
-
48
-
-
77149147406
-
Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset
-
Plaitakis A, Latsoudis H, Kanavouras K, Ritz B, Bronstein JM, Skoula I, Mastorodemos V, Papapetropoulos S, Borompokas N, Zaganas I, Xiromerisiou G, Hadjigeorgiou GM, Spanaki C. 2010. Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset. Eur J Hum Genet 18:336-341.
-
(2010)
Eur J Hum Genet
, vol.18
, pp. 336-341
-
-
Plaitakis, A.1
Latsoudis, H.2
Kanavouras, K.3
Ritz, B.4
Bronstein, J.M.5
Skoula, I.6
Mastorodemos, V.7
Papapetropoulos, S.8
Borompokas, N.9
Zaganas, I.10
Xiromerisiou, G.11
Hadjigeorgiou, G.M.12
Spanaki, C.13
-
49
-
-
80052265272
-
The human GLUD2 glutamate dehydrogenase and its regulation in health and disease
-
Plaitakis A, Latsoudis H, Spanaki C. 2011. The human GLUD2 glutamate dehydrogenase and its regulation in health and disease. Neurochem Int 59:495-509.
-
(2011)
Neurochem Int
, vol.59
, pp. 495-509
-
-
Plaitakis, A.1
Latsoudis, H.2
Spanaki, C.3
-
50
-
-
14844302859
-
Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations. J
-
Raizen DM, Brooks-Kayal A, Steinkrauss L, Tennekoon GI, Stanley CA, Kelly A. 2005. Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations. J. Pediatr 146:388-394.
-
(2005)
Pediatr
, vol.146
, pp. 388-394
-
-
Raizen, D.M.1
Brooks-Kayal, A.2
Steinkrauss, L.3
Tennekoon, G.I.4
Stanley, C.A.5
Kelly, A.6
-
51
-
-
79951659203
-
GABA transport inhibitors and seizure protection: the past and future
-
Schousboe A, Madsen KK, White HS. 2011. GABA transport inhibitors and seizure protection: the past and future. Future Med Chem 3:183-187.
-
(2011)
Future Med Chem
, vol.3
, pp. 183-187
-
-
Schousboe, A.1
Madsen, K.K.2
White, H.S.3
-
52
-
-
0021869650
-
Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders
-
Schwarcz R, Meldrum B. 1985. Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders. Lancet 2:140-143.
-
(1985)
Lancet
, vol.2
, pp. 140-143
-
-
Schwarcz, R.1
Meldrum, B.2
-
53
-
-
84865722357
-
Association of putrescine, spermidine, spermine andGABA with structural elements of brain cells
-
Seiler N, Deckardt K. 1978. Association of putrescine, spermidine, spermine andGABA with structural elements of brain cells. Neurochem Res 1:161-167.
-
(1978)
Neurochem Res
, vol.1
, pp. 161-167
-
-
Seiler, N.1
Deckardt, K.2
-
54
-
-
0028341884
-
Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene
-
Shashidharan P, Michaelidis TM, Robakis NK, Kresovali A, Papamattheakis J, Plaitakis A. 1994. Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene. J Biol Chem 269:16971-16976.
-
(1994)
J Biol Chem
, vol.269
, pp. 16971-16976
-
-
Shashidharan, P.1
Michaelidis, T.M.2
Robakis, N.K.3
Kresovali, A.4
Papamattheakis, J.5
Plaitakis, A.6
-
55
-
-
0031003604
-
Nerve tissue-specific human glutamate dehydrogenase that is thermolabile and highly regulated by ADP
-
Shashidharan P, Clarke DD, Ahmed N, Moschonas N, Plaitakis A. 1997. Nerve tissue-specific human glutamate dehydrogenase that is thermolabile and highly regulated by ADP. J Neurochem 68:1804-1811.
-
(1997)
J Neurochem
, vol.68
, pp. 1804-1811
-
-
Shashidharan, P.1
Clarke, D.D.2
Ahmed, N.3
Moschonas, N.4
Plaitakis, A.5
-
56
-
-
0014979144
-
Modifications of glutamate dehydrogenase by various drugs which affect behavior
-
Shemisa OA, Fahien LA. 1971. Modifications of glutamate dehydrogenase by various drugs which affect behavior. Mol Pharmacol 7:8-25.
-
(1971)
Mol Pharmacol
, vol.7
, pp. 8-25
-
-
Shemisa, O.A.1
Fahien, L.A.2
-
57
-
-
28444497046
-
In vivo carbon-13 magnetization transfer effect. Detection of aspartate amitransferase reaction
-
Shen J. 2005. In vivo carbon-13 magnetization transfer effect. Detection of aspartate amitransferase reaction. Magn Reson Med 54:1321-1326.
-
(2005)
Magn Reson Med
, vol.54
, pp. 1321-1326
-
-
Shen, J.1
-
58
-
-
54249092318
-
Untangling the glutamate dehydrogenase allosteric nightmare
-
Smith T, Stanley C. 2008. Untangling the glutamate dehydrogenase allosteric nightmare. Trends Biochem Sci 33:557-564.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 557-564
-
-
Smith, T.1
Stanley, C.2
-
59
-
-
0036304611
-
The structure of apo human glutamate dehydrogenase details subunit communication and allostery
-
Smith TJ, Schmidt T, Fang J, Wu J, Siuzdak G, Stanley CA. 2002. The structure of apo human glutamate dehydrogenase details subunit communication and allostery. J Mol Biol 318:765-777.
-
(2002)
J Mol Biol
, vol.318
, pp. 765-777
-
-
Smith, T.J.1
Schmidt, T.2
Fang, J.3
Wu, J.4
Siuzdak, G.5
Stanley, C.A.6
-
60
-
-
0031239422
-
Glutamate transport and metabolism in astrocytes
-
Sonnewald U, Westergaard N, Schousboe A. 1997. Glutamate transport and metabolism in astrocytes. Glia 21:56-63.
-
(1997)
Glia
, vol.21
, pp. 56-63
-
-
Sonnewald, U.1
Westergaard, N.2
Schousboe, A.3
-
61
-
-
84856303217
-
The role of glutamate dehydorgenase in mammalian ammonia metabolism
-
Spanaki C, Plaitakis A. 2012. The role of glutamate dehydorgenase in mammalian ammonia metabolism. Neurotox Res 21:117-127.
-
(2012)
Neurotox Res
, vol.21
, pp. 117-127
-
-
Spanaki, C.1
Plaitakis, A.2
-
62
-
-
77952778182
-
Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supportive cells
-
Spanaki C, Zaganas I, Kleopas K, Plaitakis A. 2010. Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supportive cells. J Biol Chem 285:16748-16756.
-
(2010)
J Biol Chem
, vol.285
, pp. 16748-16756
-
-
Spanaki, C.1
Zaganas, I.2
Kleopas, K.3
Plaitakis, A.4
-
63
-
-
84865790575
-
The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology
-
Spanaki C, Zaganas I, Kounoupa Z, Plaitakis A. 2012. The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology. Neurochem Int (in press).
-
(2012)
Neurochem Int
-
-
Spanaki, C.1
Zaganas, I.2
Kounoupa, Z.3
Plaitakis, A.4
-
64
-
-
80052259624
-
Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase
-
Stanley CA. 2011. Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase. Neurochem Int 59:465-472.
-
(2011)
Neurochem Int
, vol.59
, pp. 465-472
-
-
Stanley, C.A.1
-
65
-
-
0032493123
-
Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene
-
Stanley CA, Lieu YK, Hsu BYL, Burlina AB, Greenberg CR, Hopwood NJ, Perlman K, Rich BH, Zammarchi E, Poncz M. 1998. Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene. N Engl J Med 338:1352-1357.
-
(1998)
N Engl J Med
, vol.338
, pp. 1352-1357
-
-
Stanley, C.A.1
Lieu, Y.K.2
Hsu, B.Y.L.3
Burlina, A.B.4
Greenberg, C.R.5
Hopwood, N.J.6
Perlman, K.7
Rich, B.H.8
Zammarchi, E.9
Poncz, M.10
-
66
-
-
0034855244
-
Changing concepts in the neurochemistry of schizophrenia
-
Tamminga CA, Frost DO. 2001. Changing concepts in the neurochemistry of schizophrenia. Am J Psychiatry 158:1365-1366.
-
(2001)
Am J Psychiatry
, vol.158
, pp. 1365-1366
-
-
Tamminga, C.A.1
Frost, D.O.2
-
67
-
-
0023276014
-
Neocortical cell counts in normal human adult aging
-
Terry RD, DeTeresa R, Hansen LA. 1987. Neocortical cell counts in normal human adult aging. Ann Neurol 21:530-539.
-
(1987)
Ann Neurol
, vol.21
, pp. 530-539
-
-
Terry, R.D.1
DeTeresa, R.2
Hansen, L.A.3
-
68
-
-
7244220611
-
Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS
-
Théberge J, Al-Semaan Y, Williamson PC, Menon RS, Neufeld RW, Rajakumar N, Schaefer B, Densmore M, Drost DJ. 2003. Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS. Am J Psychiatry 160:2231-2233.
-
(2003)
Am J Psychiatry
, vol.160
, pp. 2231-2233
-
-
Théberge, J.1
Al-Semaan, Y.2
Williamson, P.C.3
Menon, R.S.4
Neufeld, R.W.5
Rajakumar, N.6
Schaefer, B.7
Densmore, M.8
Drost, D.J.9
-
69
-
-
77952626170
-
Systemic activation of glutamate dehydrogenase increases renal ammoniagenesis: implications for the hyperinsulinism/hyperammonemia syndrome
-
Treberg JR, Clow KA, Greene KA, Brosnan ME, Brosnan JT. 2010. Systemic activation of glutamate dehydrogenase increases renal ammoniagenesis: implications for the hyperinsulinism/hyperammonemia syndrome. Am J Physiol Endocrinol Metab 298:E1219-E1225.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Treberg, J.R.1
Clow, K.A.2
Greene, K.A.3
Brosnan, M.E.4
Brosnan, J.T.5
-
70
-
-
0028875197
-
Abnormal excitatory neurotransmitter metabolism in schizophrenic brains
-
Tsai G, Passani LA, Slusher BS, Carter R, Baer L, Kleinman JE, Coyle JT. 1995. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry 52:829-836.
-
(1995)
Arch Gen Psychiatry
, vol.52
, pp. 829-836
-
-
Tsai, G.1
Passani, L.A.2
Slusher, B.S.3
Carter, R.4
Baer, L.5
Kleinman, J.E.6
Coyle, J.T.7
-
71
-
-
77953076614
-
Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate
-
Wang X, Bao X, Pal R, Agbas A, Michaelis EK. 2010. Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate. BMC Genomics 11:360.
-
(2010)
BMC Genomics
, vol.11
, pp. 360
-
-
Wang, X.1
Bao, X.2
Pal, R.3
Agbas, A.4
Michaelis, E.K.5
-
72
-
-
0037135619
-
Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme
-
Zaganas I, Plaitakis A. 2002. Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme. J Biol Chem 277:26422-26428.
-
(2002)
J Biol Chem
, vol.277
, pp. 26422-26428
-
-
Zaganas, I.1
Plaitakis, A.2
-
73
-
-
0035577775
-
Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex
-
Zaganas I, Waagepetersen HS, Georgopoulos P, Sonnewald U, Plaitakis A, Schousboe A. 2001. Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex. J Neurosci Res 66:909-913.
-
(2001)
J Neurosci Res
, vol.66
, pp. 909-913
-
-
Zaganas, I.1
Waagepetersen, H.S.2
Georgopoulos, P.3
Sonnewald, U.4
Plaitakis, A.5
Schousboe, A.6
-
74
-
-
0037195942
-
Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine
-
Zaganas I, Spanaki C, Karpusas M, Plaitakis A. 2002. Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine. JBiol Chem 277:46552-46558.
-
(2002)
JBiol Chem
, vol.277
, pp. 46552-46558
-
-
Zaganas, I.1
Spanaki, C.2
Karpusas, M.3
Plaitakis, A.4
-
75
-
-
84865755077
-
Expression of human GLUD2 glutamate dehydrogenase in human tissues: functional implications
-
Zaganas I, Spanaki C, Plaitakis A. 2012. Expression of human GLUD2 glutamate dehydrogenase in human tissues: functional implications. Neurochem Int (in press).
-
(2012)
Neurochem Int
-
-
Zaganas, I.1
Spanaki, C.2
Plaitakis, A.3
|