Multigenerational effects of adolescent morphine exposure on dopamine D2 receptor function

Psychopharmacology

Volumn 227, Issue 2, 2013, Pages 263-272

  Byrnes, John J ^a   Johnson, Nicole L ^a   Carini, Lindsay M ^a   Byrnes, Elizabeth M ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Dopamine; Drug abuse; Epigenetics; Kappa receptor; Opiate; Quinpirole; Sensitization; Transgenerational

Indexed keywords

CORTICOSTERONE; DOPAMINE 2 RECEPTOR; KAPPA OPIATE RECEPTOR; QUINPIROLE;

ADOLESCENT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOSTERONE RELEASE; DNA MODIFICATION; ENZYME ACTIVATION; ENZYME REGULATION; EPIGENETICS; FEMALE; LOCOMOTION; MALE; MENTAL DISEASE; MORPHINE ADDICTION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROGENY; PROTEIN FUNCTION; RAT; SENSITIZATION;

AGE FACTORS; ANALGESICS, OPIOID; ANIMALS; BEHAVIOR, ANIMAL; DOPAMINE AGONISTS; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; MALE; MORPHINE; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; QUINPIROLE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2;

EID: 84879601509     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-012-2960-1     Document Type: Article

References (47)

1. Becker JB, Hu M (2008) Sex differences in drug abuse. Front Neuroendocrinol 29:36-47
2. Byrnes EM (2005a) Chronic morphine exposure during puberty decreases postpartum prolactin secretion in adult female rats. Pharmacol Biochem Behav 80:445-451
3. Byrnes EM (2005b) Transgenerational consequences of adolescent morphine exposure in female rats: effects on anxiety-like behaviors and morphine sensitization in adult offspring. Psychopharmacol (Berl) 182:537-544
4. Byrnes EM (2008) Chronic morphine exposure during puberty induces long-lasting changes in opioid-related mRNA expression in the mediobasal hypothalamus. Brain Res 1190:186-192
5. Byrnes JJ, Babb JA, Scanlan VF, Byrnes EM (2011) Adolescent opioid exposure in female rats: transgenerational effects on morphine analgesia and anxiety-like behavior in adult offspring. Behav Brain Res 218:200-205
6. Carpenter TL, Pazdernik TL, Levant B (2003) Differences in quinpirole-induced local cerebral glucose utilization between naive and sensitized rats. Brain Res 964:295-301
7. Crews D, Gore AC, Hsu TS, Dangleben NL, Spinetta M, Schallert T, Anway MD, Skinner MK (2007) Transgenerational epigenetic imprints on mate preference. Proc Natl Acad Sci U S A 104:5942-5946
8. Culver KE, Szechtman H (2004) Hypophysectomy does not block sensitization to the dopamine agonist quinpirole or its modulation by the MAOI clorgyline. Horm Behav 45:23-30
9. Cummings JA, Clemens LG, Nunez AA (2010) Mother counts: how effects of environmental contaminants on maternal care could affect the offspring and future generations. Front Neuroendocrinol 31:440-451
10. de Haas R, Nijdam A, Westra TA, Kas MJ, Westenberg HG (2011) Behavioral pattern analysis and dopamine release in quinpirole-induced repetitive behavior in rats. J Psychopharmacol 25:1712-1719
11. de Jong IE, Steenbergen PJ, de Kloet ER (2009) Behavioral sensitization to cocaine: cooperation between glucocorticoids and epinephrine. Psychopharmacol (Berl) 204:693-703
12. Dreher JK, Jackson DM (1989) Role of D1 and D2 dopamine receptors in mediating locomotor activity elicited from the nucleus accumbens of rats. Brain Res 487:267-277
13. Einat H, Einat D, Allan M, Talangbayan H, Tsafnat T, Szechtman H (1996) Associational and nonassociational mechanisms in locomotor sensitization to the dopamine agonist quinpirole. Psychopharmacol (Berl) 127:95-101
14. Fattore L, Altea S, Fratta W (2008) Sex differences in drug addiction: a review of animal and human studies. Womens Health (Lond Engl) 4:51-65
15. Frese WA, Eiden K (2011) Opioids: nonmedical use and abuse in older children. Pediatr Rev 32:e44-e52
16. Henry DJ, Hu XT, White FJ (1998) Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists: relevance to cocaine sensitization. Psychopharmacol (Berl) 140:233-242
17. Ho DH, Burggren WW (2010) Epigenetics and transgenerational transfer: a physiological perspective. J Exp Biol 213:3-16
18. Hummel M, Unterwald EM (2002) D1 dopamine receptor: a putative neurochemical and behavioral link to cocaine action. J Cell Physiol 191:17-27
19. Ikemoto S, Goeders NE (1998) Microinjections of dopamine agonists and cocaine elevate plasma corticosterone: dissociation effects among the ventral and dorsal striatum and medial prefrontal cortex. Brain Res 814:171-178
20. Johnson NL, Carini L, Schenk ME, Stewart M, Byrnes EM (2011) Adolescent opiate exposure in the female rat induces subtle alterations in maternal care and transgenerational effects on play behavior. Front Psychiatry 2:29
21. Koeltzow TE, Austin JD, Vezina P (2003) Behavioral sensitization to quinpirole is not associated with increased nucleus accumbens dopamine overflow. Neuropharmacology 44:102-110
22. Marinelli M, Piazza PV (2002) Interaction between glucocorticoid hormones, stress and psychostimulant drugs. Eur J Neurosci 16:387-394
23. Meriney SD, Ford MJ, Oliva D, Pilar G (1991) Endogenous opioids modulate neuronal survival in the developing avian ciliary ganglion. J Neurosci 11:3705-3717
24. Ortiz J, DeCaprio JL, Kosten TA, Nestler EJ (1995) Strain-selective effects of corticosterone on locomotor sensitization to cocaine and on levels of tyrosine hydroxylase and glucocorticoid receptor in the ventral tegmental area. Neuroscience 67:383-397
25. Perreault ML, Graham D, Bisnaire L, Simms J, Hayton S, Szechtman H (2006) Kappa-opioid agonist U69593 potentiates locomotor sensitization to the D2/D3 agonist quinpirole: pre- and postsynaptic mechanisms. Neuropsychopharmacology 31:1967-1981
26. Perreault ML, Graham D, Scattolon S, Wang Y, Szechtman H, Foster JA (2007a) Cotreatment with the kappa opioid agonist U69593 enhances locomotor sensitization to the D2/D3 dopamine agonist quinpirole and alters dopamine D2 receptor and prodynorphin mRNA expression in rats. Psychopharmacol (Berl) 194:485-496
27. Perreault ML, Seeman P, Szechtman H (2007b) Kappa-opioid receptor stimulation quickens pathogenesis of compulsive checking in the quinpirole sensitization model of obsessive-compulsive disorder (OCD). Behav Neurosci 121:976-991
28. Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45
29. Phillips GD, Howes SR, Whitelaw RB, Robbins TW, Everitt BJ (1995) Analysis of the effects of intra-accumbens SKF-38393 and LY-171555 upon the behavioural satiety sequence. Psychopharmacol (Berl) 117:82-90
30. Prasad BM, Ulibarri C, Kalivas PW, Sorg BA (1996) Effect of adrenalectomy on the initiation and expression of cocaine-induced sensitization. Psychopharmacol (Berl) 125:265-273
31. Rowlett JK, Mattingly BA, Bardo MT (1995) Repeated quinpirole treatment: locomotor activity, dopamine synthesis, and effects of selective dopamine antagonists. Synapse 20:209-216
32. SAMHSA (2011) Results from the 2010 National Survey on Drug Use and Health: summary of national findings. Substance Abuse and Mental Health Services Administration, NSDUH Series H-41 HHS Publication No. (SMA) 11-4658
33. Schmidt ED, Tilders FJ, Binnekade R, Schoffelmeer AN, De Vries TJ (1999) Stressor- or drug-induced sensitization of the corticosterone response is not critically involved in the long-term expression of behavioural sensitization to amphetamine. Neuroscience 92:343-352
34. Steiner H, Gerfen CR (1996) Dynorphin regulates D1 dopamine receptor-mediated responses in the striatum: relative contributions of pre- and postsynaptic mechanisms in dorsal and ventral striatum demonstrated by altered immediate-early gene induction. J Comp Neurol 376:530-541
35. Steketee JD, Kalivas PW (2011) Drug wanting: behavioral sensitization and relapse to drug-seeking behavior. Pharmacol Rev 63:348-365
36. Steketee JD, Sorg BA, Kalivas PW (1992) The role of the nucleus accumbens in sensitization to drugs of abuse. Prog Neuropsychopharmacol Biol Psychiatry 16:237-246
37. Szechtman H, Talangbayan H, Eilam D (1993) Environmental and behavioral components of sensitization induced by the dopamine agonist quinpirole. Behav Pharmacol 4:405-410
38. Szumlinski KK, Allan M, Talangbayan H, Tracey A, Szechtman H (1997) Locomotor sensitization to quinpirole: environment-modulated increase in efficacy and context-dependent increase in potency. Psychopharmacol (Berl) 134:193-200
39. Szumlinski KK, Goodwill AM, Szechtman H (2000) Locomotor sensitization to quinpirole in rats: effects of drug abstinence and sex. Psychopharmacol (Berl) 152:304-311
40. Taepavarapruk P, Floresco SB, Phillips AG (2000) Hyperlocomotion and increased dopamine efflux in the rat nucleus accumbens evoked by electrical stimulation of the ventral subiculum: role of ionotropic glutamate and dopamine D1 receptors. Psychopharmacol (Berl) 151:242-251
41. Vanderschuren LJ, Kalivas PW (2000) Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacol (Berl) 151:99-120
42. Vernadakis A, Sakellaridis N, Geladopoulos T, Mangoura D (1990) Function of opioids early in embryogenesis. Ann N Y Acad Sci 579:109-122
43. Wise RA, Leeb K (1993) Psychomotor-stimulant sensitization: a unitary phenomenon? Behav Pharmacol 4:339-349
44. Wrobel A, Zebrowska-Lupina I, Wielosz M (2005) Dexamethasone reduces locomotor stimulation induced by dopamine agonists in mice. Pharmacol Rep 57:451-457
45. Wu M, Brudzynski SM, Mogenson GJ (1993) Differential effects of quinpirole in the nucleus accumbens depending on the initial level of locomotor activity. Brain Res Bull 32:395-398
46. Zagon IS, Tobias SW, McLaughlin PJ (1997) Endogenous opioids and prenatal determinants of neuroplasticity. Adv Exp Med Biol 429:289-303
47. Zagon IS, Wu Y, McLaughlin PJ (1999) Opioid growth factor and organ development in rat and human embryos. Brain Res 839:313-322