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Volumn 117, Issue 1, 2011, Pages 323-332

Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes

Author keywords

[No Author keywords available]

Indexed keywords

COBALT CHLORIDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; JANUS KINASE 2; OXYGEN; SMALL INTERFERING RNA; STAT5 PROTEIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1;

EID: 78650985962     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-01-261792     Document Type: Article
Times cited : (84)

References (28)
  • 1
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 1992;359(6398):843-845.
    • (1992) Nature , vol.359 , Issue.6398 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 2
    • 0030968939 scopus 로고    scopus 로고
    • Targeting gene expression to hypoxic tumor cells
    • Dachs GU, Patterson AV, Firth JD, et al. Targeting gene expression to hypoxic tumor cells. Nat Med. 1997;3(5):515-520.
    • (1997) Nat Med , vol.3 , Issue.5 , pp. 515-520
    • Dachs, G.U.1    Patterson, A.V.2    Firth, J.D.3
  • 3
    • 0034671256 scopus 로고    scopus 로고
    • Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines
    • Blancher C, Moore JW, Talks KL, Houlbrook S, Harris AL. Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines. Cancer Res. 2000;60(24):7106-7113.
    • (2000) Cancer Res , vol.60 , Issue.24 , pp. 7106-7113
    • Blancher, C.1    Moore, J.W.2    Talks, K.L.3    Houlbrook, S.4    Harris, A.L.5
  • 4
    • 54849419891 scopus 로고    scopus 로고
    • Microarray analyses of hypoxia-regulated genes in an aryl hydrocarbon receptor nuclear translocator (Arnt)-dependent manner
    • Choi SM, Oh H, Park H. Microarray analyses of hypoxia-regulated genes in an aryl hydrocarbon receptor nuclear translocator (Arnt)-dependent manner. FEBS J. 2008;275(22):5618-5634.
    • (2008) FEBS J , vol.275 , Issue.22 , pp. 5618-5634
    • Choi, S.M.1    Oh, H.2    Park, H.3
  • 5
    • 68249140395 scopus 로고    scopus 로고
    • Hypoxiainducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
    • Fang HY, Hughes R, Murdoch C, et al. Hypoxiainducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Blood. 2009;114(4):844-859.
    • (2009) Blood , vol.114 , Issue.4 , pp. 844-859
    • Fang, H.Y.1    Hughes, R.2    Murdoch, C.3
  • 6
    • 0001952158 scopus 로고    scopus 로고
    • Soluble VEGF receptors
    • Hornig C, Weich HA. Soluble VEGF receptors. Angiogenesis. 1999;3(1):33-39.
    • (1999) Angiogenesis , vol.3 , Issue.1 , pp. 33-39
    • Hornig, C.1    Weich, H.A.2
  • 7
    • 58549096730 scopus 로고    scopus 로고
    • Prognostic and predictive value of vascular endothelial growth factor and its soluble receptors, VEGFR-1 and VEGFR-2 levels in the sera of small cell lung cancer patients
    • Ustuner Z, Saip P, Yasasever V, et al. Prognostic and predictive value of vascular endothelial growth factor and its soluble receptors, VEGFR-1 and VEGFR-2 levels in the sera of small cell lung cancer patients. Med Oncol. 2008;25(4):394-399.
    • (2008) Med Oncol , vol.25 , Issue.4 , pp. 394-399
    • Ustuner, Z.1    Saip, P.2    Yasasever, V.3
  • 8
    • 15244362063 scopus 로고    scopus 로고
    • Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer
    • Bando H, Weich HA, Brokelmann M, et al. Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer. Br J Cancer. 2005;92(3):553-561.
    • (2005) Br J Cancer , vol.92 , Issue.3 , pp. 553-561
    • Bando, H.1    Weich, H.A.2    Brokelmann, M.3
  • 9
    • 10344251488 scopus 로고    scopus 로고
    • GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice
    • Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity. 2004;21(6):831-842.
    • (2004) Immunity , vol.21 , Issue.6 , pp. 831-842
    • Eubank, T.D.1    Roberts, R.2    Galloway, M.3    Wang, Y.4    Cohn, D.E.5    Marsh, C.B.6
  • 10
    • 33846075802 scopus 로고    scopus 로고
    • The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival
    • Wang Y, Zeigler MM, Lam GK, et al. The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival. Am J Respir Cell Mol Biol. 2007;36(1):68-77.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , Issue.1 , pp. 68-77
    • Wang, Y.1    Zeigler, M.M.2    Lam, G.K.3
  • 11
    • 0037423948 scopus 로고    scopus 로고
    • HIF-1alpha is essential for myeloid cell-mediated inflammation
    • Cramer T, Yamanishi Y, Clausen BE, et al. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 2003;112(5):645-657.
    • (2003) Cell , vol.112 , Issue.5 , pp. 645-657
    • Cramer, T.1    Yamanishi, Y.2    Clausen, B.E.3
  • 12
    • 59849090604 scopus 로고    scopus 로고
    • Novel splice variants of sFlt1 are upregulated in preeclampsia
    • Heydarian M, McCaffrey T, Florea L, et al. Novel splice variants of sFlt1 are upregulated in preeclampsia. Placenta. 2009;30(3):250-255.
    • (2009) Placenta , vol.30 , Issue.3 , pp. 250-255
    • Heydarian, M.1    McCaffrey, T.2    Florea, L.3
  • 13
    • 27744501438 scopus 로고    scopus 로고
    • Regulation of soluble vascular endothelial growth factor receptor (sFlt-1/sVEGFR-1) expression and release in endothelial cells by human follicular fluid and granulosa cells
    • Gruemmer R, Motejlek K, Berghaus D,Weich HA, Neulen J. Regulation of soluble vascular endothelial growth factor receptor (sFlt-1/sVEGFR-1) expression and release in endothelial cells by human follicular fluid and granulosa cells. Reprod Biol Endocrinol. 2005;3:57.
    • (2005) Reprod Biol Endocrinol , vol.3 , pp. 57
    • Gruemmer, R.1    Motejlek, K.2    Berghaus, D.3    Weich, H.A.4    Neulen, J.5
  • 15
    • 27744603002 scopus 로고    scopus 로고
    • Hypoxia regulates macrophage functions in inflammation
    • Murdoch C, Muthana M, Lewis CE. Hypoxia regulates macrophage functions in inflammation. J Immunol. 2005;175(10):6257-6263.
    • (2005) J Immunol , vol.175 , Issue.10 , pp. 6257-6263
    • Murdoch, C.1    Muthana, M.2    Lewis, C.E.3
  • 16
    • 0025907181 scopus 로고
    • Lack of effect of granulocyte-macrophage and granulocyte colony-stimulating factors on cultured human endothelial cells
    • Yong K, Cohen H, Khwaja A, Jones HM, Linch DC. Lack of effect of granulocyte-macrophage and granulocyte colony-stimulating factors on cultured human endothelial cells. Blood. 1991;77(8):1675-1680.
    • (1991) Blood , vol.77 , Issue.8 , pp. 1675-1680
    • Yong, K.1    Cohen, H.2    Khwaja, A.3    Jones, H.M.4    Linch, D.C.5
  • 17
    • 0344873719 scopus 로고    scopus 로고
    • Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells
    • Joung YH, Park JH, Park T, et al. Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells. Exp Mol Med. 2003;35(5):350-357.
    • (2003) Exp Mol Med , vol.35 , Issue.5 , pp. 350-357
    • Joung, Y.H.1    Park, J.H.2    Park, T.3
  • 19
    • 62449179631 scopus 로고    scopus 로고
    • Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages
    • Eubank TD, Roberts RD, Khan M, et al. Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages. Cancer Res. 2009;69(5):2133-2140.
    • (2009) Cancer Res , vol.69 , Issue.5 , pp. 2133-2140
    • Eubank, T.D.1    Roberts, R.D.2    Khan, M.3
  • 20
    • 0032867830 scopus 로고    scopus 로고
    • Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: Association with angiogenesis and poor prognosis
    • Takanami I, Takeuchi K, Kodaira S. Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis. Oncology. 1999;57(2):138-142.
    • (1999) Oncology , vol.57 , Issue.2 , pp. 138-142
    • Takanami, I.1    Takeuchi, K.2    Kodaira, S.3
  • 21
    • 0031985128 scopus 로고    scopus 로고
    • Granulocytemacrophage colony-stimulating factor-activated signaling pathways in human neutrophils: Selective activation of Jak2, Stat3, and Stat5b
    • Al-Shami A, MahannaW, Naccache PH. Granulocytemacrophage colony-stimulating factor-activated signaling pathways in human neutrophils: selective activation of Jak2, Stat3, and Stat5b. J Biol Chem. 1998;273(2):1058-1063.
    • (1998) J Biol Chem , vol.273 , Issue.2 , pp. 1058-1063
    • Al-Shami, A.1    Mahanna, W.2    Naccache, P.H.3
  • 22
    • 0036521607 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and targetgene expression during human monocyte/macrophage differentiation
    • Lehtonen A, Matikainen S, Miettinen M, Julkunen I. Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and targetgene expression during human monocyte/macrophage differentiation. J Leukoc Biol. 2002;71(3):511-519.
    • (2002) J Leukoc Biol , vol.71 , Issue.3 , pp. 511-519
    • Lehtonen, A.1    Matikainen, S.2    Miettinen, M.3    Julkunen, I.4
  • 23
    • 64649083602 scopus 로고    scopus 로고
    • Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis
    • Guimbellot JS, Erickson SW, Mehta T, et al. Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis. BMC Med Genom. 2009;2:15.
    • (2009) BMC Med Genom , vol.2 , pp. 15
    • Guimbellot, J.S.1    Erickson, S.W.2    Mehta, T.3
  • 24
    • 0030792590 scopus 로고    scopus 로고
    • A family of cytokine-inducible inhibitors of signalling
    • Starr R, Willson TA, Viney EM, et al. A family of cytokine-inducible inhibitors of signalling. Nature. 1997;387(6636):917-921.
    • (1997) Nature , vol.387 , Issue.6636 , pp. 917-921
    • Starr, R.1    Willson, T.A.2    Viney, E.M.3
  • 25
    • 0141988698 scopus 로고    scopus 로고
    • Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia
    • Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL. Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. Cancer Res. 2003;63(19):6130-6134.
    • (2003) Cancer Res , vol.63 , Issue.19 , pp. 6130-6134
    • Sowter, H.M.1    Raval, R.R.2    Moore, J.W.3    Ratcliffe, P.J.4    Harris, A.L.5
  • 26
    • 0036493984 scopus 로고    scopus 로고
    • Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
    • Leek RD, Talks KL, Pezzella F, et al. Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer. Cancer Res. 2002;62(5):1326-1329.
    • (2002) Cancer Res , vol.62 , Issue.5 , pp. 1326-1329
    • Leek, R.D.1    Talks, K.L.2    Pezzella, F.3
  • 27
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
    • Talks KL, Turley H, Gatter KC, et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol. 2000;157(2):411-421.
    • (2000) Am J Pathol , vol.157 , Issue.2 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3
  • 28
    • 59649117924 scopus 로고    scopus 로고
    • Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization
    • Mazzone M, Dettori D, Leite de Oliveira R, et al. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization. Cell. 2009;136(5):839-851.
    • (2009) Cell , vol.136 , Issue.5 , pp. 839-851
    • Mazzone, M.1    Dettori, D.2    Leite De Oliveira, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.