메뉴 건너뛰기




Volumn 91, Issue 4, 2013, Pages 459-472

Fenretinide sensitizes multidrug-resistant human neuroblastoma cells to antibody-independent and ch14.18-mediated NK cell cytotoxicity

Author keywords

ADCC; ch14.18; Fenretinide; Immunotherapy; Neuroblastoma

Indexed keywords

FENRETINIDE;

EID: 84879600767     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-012-0958-0     Document Type: Article
Times cited : (19)

References (38)
  • 1
    • 0037190798 scopus 로고    scopus 로고
    • Genetic parameters of neuroblastomas
    • 12127685 10.1016/S0304-3835(02)00199-4 1:CAS:528:DC%2BD38XlsVKmuro%3D
    • Westermann F, Schwab M (2002) Genetic parameters of neuroblastomas. Cancer Lett 184:127-147
    • (2002) Cancer Lett , vol.184 , pp. 127-147
    • Westermann, F.1    Schwab, M.2
  • 2
    • 77957341503 scopus 로고    scopus 로고
    • Chimeric anti-GD2 antibody with GM-CSF, IL2 and 13-cis retinoic acid for high-risk neuroblastoma: A Children's Oncology Group (COG) phase 3 study
    • 20879881 10.1056/NEJMoa0911123 1:CAS:528:DC%2BC3cXht1WqtrnP
    • Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman S, Chen H, Smith M, Anderson B, Villablanca J, Matthay KK et al (2010) Chimeric anti-GD2 antibody with GM-CSF, IL2 and 13-cis retinoic acid for high-risk neuroblastoma: a Children's Oncology Group (COG) phase 3 study. N Engl J Med 363(14):1324-1334
    • (2010) N Engl J Med , vol.363 , Issue.14 , pp. 1324-1334
    • Yu, A.L.1    Gilman, A.L.2    Ozkaynak, M.F.3    London, W.B.4    Kreissman, S.5    Chen, H.6    Smith, M.7    Anderson, B.8    Villablanca, J.9    Matthay, K.K.10
  • 3
    • 0021726250 scopus 로고
    • Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients
    • 6498849 1:STN:280:DyaL2M%2FkvVOkuw%3D%3D
    • Schulz G, Cheresh DA, Varki NM, Yu A, Staffileno LK, Reisfeld RA (1984) Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients. Cancer Res 44(12 Pt 1):5914-5920
    • (1984) Cancer Res , vol.44 , Issue.12 PART 1 , pp. 5914-5920
    • Schulz, G.1    Cheresh, D.A.2    Varki, N.M.3    Yu, A.4    Staffileno, L.K.5    Reisfeld, R.A.6
  • 4
    • 0028095104 scopus 로고
    • Gangliosides and allied glycosphingolipids in human peripheral nerve and spinal cord
    • 7918590 10.1016/0005-2760(94)90034-5 1:CAS:528:DyaK2cXmtVWnsLg%3D
    • Svennerholm L, Bostrom K, Fredman P, Jungbjer B, Lekman A, Mansson JE, Rynmark BM (1994) Gangliosides and allied glycosphingolipids in human peripheral nerve and spinal cord. Biochim Biophys Acta 1214(2):115-123
    • (1994) Biochim Biophys Acta , vol.1214 , Issue.2 , pp. 115-123
    • Svennerholm, L.1    Bostrom, K.2    Fredman, P.3    Jungbjer, B.4    Lekman, A.5    Mansson, J.E.6    Rynmark, B.M.7
  • 6
    • 33745528911 scopus 로고    scopus 로고
    • FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor
    • Cheung NK, Sowers R, Vickers AJ, Cheung IY, Kushner BH, Gorlick R (2006) FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor. J Clin Oncol 24(18):2885-2890
    • (2006) J Clin Oncol , vol.24 , Issue.18 , pp. 2885-2890
    • Cheung, N.K.1    Sowers, R.2    Vickers, A.J.3    Cheung, I.Y.4    Kushner, B.H.5    Gorlick, R.6
  • 7
    • 38049103314 scopus 로고    scopus 로고
    • Mechanisms of granule-dependent killing
    • 17975553 10.1038/sj.cdd.4402244 1:CAS:528:DC%2BD1cXmsVOrsQ%3D%3D
    • Cullen SP, Martin SJ (2008) Mechanisms of granule-dependent killing. Cell Death Differ 15(2):251-262
    • (2008) Cell Death Differ , vol.15 , Issue.2 , pp. 251-262
    • Cullen, S.P.1    Martin, S.J.2
  • 8
    • 0032526268 scopus 로고    scopus 로고
    • Apoptosis signaling by death receptors
    • 9688254 10.1046/j.1432-1327.1998.2540439.x 1:CAS:528:DyaK1cXktlertrw%3D
    • Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S, Peter ME (1998) Apoptosis signaling by death receptors. Eur J Biochem 254(3):439-459
    • (1998) Eur J Biochem , vol.254 , Issue.3 , pp. 439-459
    • Schulze-Osthoff, K.1    Ferrari, D.2    Los, M.3    Wesselborg, S.4    Peter, M.E.5
  • 9
    • 57049155399 scopus 로고    scopus 로고
    • Directing cancer cells to self-destruct with pro-apoptotic receptor agonists
    • 18989337 10.1038/nrd2637 1:CAS:528:DC%2BD1cXhsVSjsbnF
    • Ashkenazi A (2008) Directing cancer cells to self-destruct with pro-apoptotic receptor agonists. Nat Rev Drug Discov 7(12):1001-1012
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.12 , pp. 1001-1012
    • Ashkenazi, A.1
  • 11
    • 33746799839 scopus 로고    scopus 로고
    • Phase i trial of oral fenretinide in children with high-risk solid tumors: A report from the Children's Oncology Group (CCG 09709)
    • 16849757 10.1200/JCO.2005.03.9271 1:CAS:528:DC%2BD28Xot1KisL0%3D
    • Villablanca JG, Krailo MD, Ames MM, Reid JM, Reaman GH, Reynolds CP (2006) Phase I trial of oral fenretinide in children with high-risk solid tumors: a report from the Children's Oncology Group (CCG 09709). J Clin Oncol 24(21):3423-3430
    • (2006) J Clin Oncol , vol.24 , Issue.21 , pp. 3423-3430
    • Villablanca, J.G.1    Krailo, M.D.2    Ames, M.M.3    Reid, J.M.4    Reaman, G.H.5    Reynolds, C.P.6
  • 12
    • 0033532912 scopus 로고    scopus 로고
    • Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)-retinamide in neuroblastoma cell lines
    • 10393722 10.1093/jnci/91.13.1138 1:CAS:528:DyaK1MXkvVyjs7o%3D
    • Maurer BJ, Metelitsa LS, Seeger RC, Cabot MC, Reynolds CP (1999) Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines. J Natl Cancer Inst 91(13):1138-1146
    • (1999) J Natl Cancer Inst , vol.91 , Issue.13 , pp. 1138-1146
    • Maurer, B.J.1    Metelitsa, L.S.2    Seeger, R.C.3    Cabot, M.C.4    Reynolds, C.P.5
  • 13
    • 77953303657 scopus 로고    scopus 로고
    • Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells
    • 20404323 10.1074/jbc.M109.072801 1:CAS:528:DC%2BC3cXmvFaqsLg%3D
    • Illuzzi G, Bernacchioni C, Aureli M, Prioni S, Frera G, Donati C, Valsecchi M, Chigorno V, Bruni P, Sonnino S et al (2010) Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells. J Biol Chem 285(24):18594-18602
    • (2010) J Biol Chem , vol.285 , Issue.24 , pp. 18594-18602
    • Illuzzi, G.1    Bernacchioni, C.2    Aureli, M.3    Prioni, S.4    Frera, G.5    Donati, C.6    Valsecchi, M.7    Chigorno, V.8    Bruni, P.9    Sonnino, S.10
  • 15
    • 12244284610 scopus 로고    scopus 로고
    • Possible role of ceramide as an indicator of chemoresistance: Decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia
    • 12538495 1:CAS:528:DC%2BD3sXnt1OqtQ%3D%3D
    • Itoh M, Kitano T, Watanabe M, Kondo T, Yabu T, Taguchi Y, Iwai K, Tashima M, Uchiyama T, Okazaki T (2003) Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia. Clin Cancer Res 9(1):415-423
    • (2003) Clin Cancer Res , vol.9 , Issue.1 , pp. 415-423
    • Itoh, M.1    Kitano, T.2    Watanabe, M.3    Kondo, T.4    Yabu, T.5    Taguchi, Y.6    Iwai, K.7    Tashima, M.8    Uchiyama, T.9    Okazaki, T.10
  • 16
    • 33845346454 scopus 로고    scopus 로고
    • Glycosphingolipids and drug resistance
    • 17010304 10.1016/j.bbamem.2006.08.012 1:CAS:528:DC%2BD28Xht12kt73N
    • Gouaze-Andersson V, Cabot MC (2006) Glycosphingolipids and drug resistance. Biochim Biophys Acta 1758(12):2096-2103
    • (2006) Biochim Biophys Acta , vol.1758 , Issue.12 , pp. 2096-2103
    • Gouaze-Andersson, V.1    Cabot, M.C.2
  • 17
    • 0034629305 scopus 로고    scopus 로고
    • Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance
    • 10702281 10.1074/jbc.275.10.7138 1:CAS:528:DC%2BD3cXhvVGkurg%3D
    • Liu YY, Han TY, Giuliano AE, Hansen N, Cabot MC (2000) Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance. J Biol Chem 275(10):7138-7143
    • (2000) J Biol Chem , vol.275 , Issue.10 , pp. 7138-7143
    • Liu, Y.Y.1    Han, T.Y.2    Giuliano, A.E.3    Hansen, N.4    Cabot, M.C.5
  • 18
    • 4444346464 scopus 로고    scopus 로고
    • Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide
    • 15339967 10.1093/jnci/djh254 1:CAS:528:DC%2BD2cXnsVyht7Y%3D
    • Lovat PE, Di SF, Corazzari M, Fazi B, Donnorso RP, Pearson AD, Hall AG, Redfern CP, Piacentini M (2004) Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide. J Natl Cancer Inst 96(17):1288-1299
    • (2004) J Natl Cancer Inst , vol.96 , Issue.17 , pp. 1288-1299
    • Lovat, P.E.1    Di, S.F.2    Corazzari, M.3    Fazi, B.4    Donnorso, R.P.5    Pearson, A.D.6    Hall, A.G.7    Redfern, C.P.8    Piacentini, M.9
  • 19
    • 77958610760 scopus 로고    scopus 로고
    • Fenretinide-dependent upregulation of death receptors through ASK1 and p38alpha enhances death receptor ligand-induced cell death in Ewing's sarcoma family of tumours
    • White DE, Burchill SA (2010) Fenretinide-dependent upregulation of death receptors through ASK1 and p38alpha enhances death receptor ligand-induced cell death in Ewing's sarcoma family of tumours. Br J Cancer 103:1380-1390
    • (2010) Br J Cancer , vol.103 , pp. 1380-1390
    • White, D.E.1    Burchill, S.A.2
  • 20
    • 0033646876 scopus 로고    scopus 로고
    • Retinoic-acid-resistant neuroblastoma cell lines show altered MYC regulation and high sensitivity to fenretinide
    • 11107126 10.1002/1096-911X(20001201)35:6<597: AID-MPO23>3.0.CO;2-B 1:STN:280:DC%2BD3M7htVCnug%3D%3D
    • Reynolds CP, Wang Y, Melton LJ, Einhorn PA, Slamon DJ, Maurer BJ (2000) Retinoic-acid-resistant neuroblastoma cell lines show altered MYC regulation and high sensitivity to fenretinide. Med Pediatr Oncol 35:597-602
    • (2000) Med Pediatr Oncol , vol.35 , pp. 597-602
    • Reynolds, C.P.1    Wang, Y.2    Melton, L.J.3    Einhorn, P.A.4    Slamon, D.J.5    Maurer, B.J.6
  • 22
    • 80055116109 scopus 로고    scopus 로고
    • Expansion, purification, and functional assessment of human peripheral blood NK cells
    • doi: 10.3791/2540
    • Somanchi SS, Senyukov VV, Denman CJ, Lee DA (2011) Expansion, purification, and functional assessment of human peripheral blood NK cells. J Vis Exp (48). doi: 10.3791/2540
    • (2011) J Vis Exp , Issue.48
    • Somanchi, S.S.1    Senyukov, V.V.2    Denman, C.J.3    Lee, D.A.4
  • 23
    • 0041695940 scopus 로고    scopus 로고
    • An economical adaptation of the RosetteSep procedure for NK cell enrichment from whole blood, and its use with liquid nitrogen stored peripheral blood mononuclear cells
    • 12972194 10.1016/S0022-1759(03)00106-6 1:CAS:528:DC%2BD3sXntVygsbw%3D
    • Warren HS, Rana PM (2003) An economical adaptation of the RosetteSep procedure for NK cell enrichment from whole blood, and its use with liquid nitrogen stored peripheral blood mononuclear cells. J Immunol Methods 280(1-2):135-138
    • (2003) J Immunol Methods , vol.280 , Issue.1-2 , pp. 135-138
    • Warren, H.S.1    Rana, P.M.2
  • 25
    • 0034616635 scopus 로고    scopus 로고
    • Influence of cellular ganglioside depletion on tumor formation
    • 10841826 10.1093/jnci/92.11.912 1:CAS:528:DC%2BD3cXksF2qur8%3D
    • Deng W, Li R, Ladisch S (2000) Influence of cellular ganglioside depletion on tumor formation. J Natl Cancer Inst 92(11):912-917
    • (2000) J Natl Cancer Inst , vol.92 , Issue.11 , pp. 912-917
    • Deng, W.1    Li, R.2    Ladisch, S.3
  • 26
    • 34249818765 scopus 로고    scopus 로고
    • Improved oral delivery of N-(4-hydroxyphenyl)retinamide with a novel LYM-X-SORB organized lipid complex
    • 17505011 10.1158/1078-0432.CCR-06-1889 1:CAS:528:DC%2BD2sXlt1Krtb0%3D
    • Marachelian A, Kang MH, Hwang K, Villablanca JG, Groshen S, Matthay KK, Maris JM, Desantis KB, Reynolds CP, Maurer BJ (2009) Phase I study of fenretinide (4-HPR) oral powder in patients with recurrent or resistant neuroblastoma: New Approaches to Neuroblastoma Therapy (NANT) Consortium trial. J Clin Oncol 27:15S, abstr 10009
    • (2007) Clin Cancer Res , vol.13 , Issue.10 , pp. 3079-3086
    • Maurer, B.J.1    Kalous, O.2    Yesair, D.W.3    Wu, X.4    Janeba, J.5    Maldonado, V.6    Khankaldyyan, V.7    Frgala, T.8    Sun, B.C.9    McKee, R.T.10
  • 27
    • 0034886524 scopus 로고    scopus 로고
    • Ganglioside GM2/GD2 synthetase mRNA is a marker for detection of infrequent neuroblastoma cells in bone marrow
    • 11485908 10.1016/S0002-9440(10)61721-X 1:CAS:528:DC%2BD3MXms1WisbY%3D
    • Hoon DS, Kuo CT, Wen S, Wang H, Metelitsa L, Reynolds CP, Seeger RC (2001) Ganglioside GM2/GD2 synthetase mRNA is a marker for detection of infrequent neuroblastoma cells in bone marrow. Am J Pathol 159(2):493-500
    • (2001) Am J Pathol , vol.159 , Issue.2 , pp. 493-500
    • Hoon, D.S.1    Kuo, C.T.2    Wen, S.3    Wang, H.4    Metelitsa, L.5    Reynolds, C.P.6    Seeger, R.C.7
  • 28
    • 43149117910 scopus 로고    scopus 로고
    • Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation
    • 18398104 10.1093/jnci/djn076 1:CAS:528:DC%2BD1cXkvFOlsLY%3D
    • Kang MH, Wan Z, Kang YH, Sposto R, Reynolds CP (2008) Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation. J Natl Cancer Inst 100:580-595
    • (2008) J Natl Cancer Inst , vol.100 , pp. 580-595
    • Kang, M.H.1    Wan, Z.2    Kang, Y.H.3    Sposto, R.4    Reynolds, C.P.5
  • 29
    • 58149329110 scopus 로고    scopus 로고
    • Phase i study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: A report from the Children's Oncology Group
    • 19047298 10.1200/JCO.2006.10.3564 1:CAS:528:DC%2BD1MXhs1Gnsb0%3D
    • Gilman AL, Ozkaynak MF, Matthay KK, Krailo M, Yu AL, Gan J, Sternberg A, Hank JA, Seeger R, Reaman GH et al (2009) Phase I study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: a report from the Children's Oncology Group. J Clin Oncol 27(1):85-91
    • (2009) J Clin Oncol , vol.27 , Issue.1 , pp. 85-91
    • Gilman, A.L.1    Ozkaynak, M.F.2    Matthay, K.K.3    Krailo, M.4    Yu, A.L.5    Gan, J.6    Sternberg, A.7    Hank, J.A.8    Seeger, R.9    Reaman, G.H.10
  • 31
    • 79955761920 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95- and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex
    • 21454681 10.1074/jbc.M110.148585 1:CAS:528:DC%2BC3MXlslKlsr4%3D
    • Kavuri SM, Geserick P, Berg D, Dimitrova DP, Feoktistova M, Siegmund D, Gollnick H, Neumann M, Wajant H, Leverkus M (2011) Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95- and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex. J Biol Chem 286(19):16631-16646
    • (2011) J Biol Chem , vol.286 , Issue.19 , pp. 16631-16646
    • Kavuri, S.M.1    Geserick, P.2    Berg, D.3    Dimitrova, D.P.4    Feoktistova, M.5    Siegmund, D.6    Gollnick, H.7    Neumann, M.8    Wajant, H.9    Leverkus, M.10
  • 32
    • 33947289558 scopus 로고    scopus 로고
    • Fractalkine (CX3CL1)- and interleukin-2-enriched neuroblastoma microenvironment induces eradication of metastases mediated by T cells and natural killer cells
    • 17332365 10.1158/0008-5472.CAN-06-3041 1:CAS:528:DC%2BD2sXitlSjsLY%3D
    • Zeng Y, Huebener N, Fest S, Weixler S, Schroeder U, Gaedicke G, Xiang R, Schramm A, Eggert A, Reisfeld RA et al (2007) Fractalkine (CX3CL1)- and interleukin-2-enriched neuroblastoma microenvironment induces eradication of metastases mediated by T cells and natural killer cells. Cancer Res 67(5):2331-2338
    • (2007) Cancer Res , vol.67 , Issue.5 , pp. 2331-2338
    • Zeng, Y.1    Huebener, N.2    Fest, S.3    Weixler, S.4    Schroeder, U.5    Gaedicke, G.6    Xiang, R.7    Schramm, A.8    Eggert, A.9    Reisfeld, R.A.10
  • 33
    • 0035999738 scopus 로고    scopus 로고
    • Oral (1→3),(1→4)-beta-d-glucan synergizes with antiganglioside GD2 monoclonal antibody 3F8 in the therapy of neuroblastoma
    • 12006541 1:CAS:528:DC%2BD38XksVWjsrg%3D
    • Cheung NK, Modak S (2002) Oral (1→3),(1→4)-beta-d-glucan synergizes with antiganglioside GD2 monoclonal antibody 3F8 in the therapy of neuroblastoma. Clin Cancer Res 8(5):1217-1223
    • (2002) Clin Cancer Res , vol.8 , Issue.5 , pp. 1217-1223
    • Cheung, N.K.1    Modak, S.2
  • 34
    • 0037458741 scopus 로고    scopus 로고
    • Altered sphingolipid metabolism in N-(4-hydroxyphenyl)-retinamide- resistant A2780 human ovarian carcinoma cells
    • 12486134 10.1074/jbc.M207269200 1:CAS:528:DC%2BD3sXht1aqs70%3D
    • Prinetti A, Basso L, Appierto V, Villani MG, Valsecchi M, Loberto N, Prioni S, Chigorno V, Cavadini E, Formelli F et al (2003) Altered sphingolipid metabolism in N-(4-hydroxyphenyl)-retinamide-resistant A2780 human ovarian carcinoma cells. J Biol Chem 278(8):5574-5583
    • (2003) J Biol Chem , vol.278 , Issue.8 , pp. 5574-5583
    • Prinetti, A.1    Basso, L.2    Appierto, V.3    Villani, M.G.4    Valsecchi, M.5    Loberto, N.6    Prioni, S.7    Chigorno, V.8    Cavadini, E.9    Formelli, F.10
  • 35
    • 0034614095 scopus 로고    scopus 로고
    • Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism
    • 11106681 10.1093/jnci/92.23.1897 1:CAS:528:DC%2BD3cXptVehu7g%3D
    • Maurer BJ, Melton L, Billups C, Cabot MC, Reynolds CP (2000) Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism. J Natl Cancer Inst 92(23):1897-1909
    • (2000) J Natl Cancer Inst , vol.92 , Issue.23 , pp. 1897-1909
    • Maurer, B.J.1    Melton, L.2    Billups, C.3    Cabot, M.C.4    Reynolds, C.P.5
  • 36
    • 33947719084 scopus 로고    scopus 로고
    • Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines
    • 17273769 1:CAS:528:DC%2BD2sXjtFGgtb0%3D
    • Kouhara J, Yoshida T, Nakata S, Horinaka M, Wakada M, Ueda Y, Yamagishi H, Sakai T (2007) Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines. Int J Oncol 30(3):679-687
    • (2007) Int J Oncol , vol.30 , Issue.3 , pp. 679-687
    • Kouhara, J.1    Yoshida, T.2    Nakata, S.3    Horinaka, M.4    Wakada, M.5    Ueda, Y.6    Yamagishi, H.7    Sakai, T.8
  • 37
    • 2442697830 scopus 로고    scopus 로고
    • N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines
    • 14765134 10.1038/sj.cdd.4401387 1:CAS:528:DC%2BD2cXjtFOitrw%3D
    • Cuello M, Coats AO, Darko I, Ettenberg SA, Gardner GJ, Nau MM, Liu JR, Birrer MJ, Lipkowitz S (2004) N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines. Cell Death Differ 11(5):527-541
    • (2004) Cell Death Differ , vol.11 , Issue.5 , pp. 527-541
    • Cuello, M.1    Coats, A.O.2    Darko, I.3    Ettenberg, S.A.4    Gardner, G.J.5    Nau, M.M.6    Liu, J.R.7    Birrer, M.J.8    Lipkowitz, S.9
  • 38
    • 23944450395 scopus 로고    scopus 로고
    • MIC and other NKG2D ligands: From none to too many
    • 16087327 10.1016/j.coi.2005.07.016 1:CAS:528:DC%2BD2MXpslyiu7c%3D
    • Bahram S, Inoko H, Shiina T, Radosavljevic M (2005) MIC and other NKG2D ligands: from none to too many. Curr Opin Immunol 17(5):505-509
    • (2005) Curr Opin Immunol , vol.17 , Issue.5 , pp. 505-509
    • Bahram, S.1    Inoko, H.2    Shiina, T.3    Radosavljevic, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.