Development of flavonoid-based inverse agonists of the key signaling receptor US28 of human cytomegalovirus

Journal of Medicinal Chemistry

Volumn 56, Issue 12, 2013, Pages 5019-5032

  Kralj, Ana ^a   Nguyen, Mai Thao ^b   Tschammer, Nuska ^a   Ocampo, Nicolette ^c   Gesiotto, Quinto ^c   Heinrich, Markus R ^a   Phanstiel, Otto ^c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF FLORIDA HEALTH   (United States)

^c UNIVERSITY OF CENTRAL FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (BENZYLOXY) 2 (5 BROMO 2 METHOXYPHENYL) 4H CHROMEN 4 ONE; ACETOPHENONE; ANTIVIRUS AGENT; BENZALDEHYDE DEHYDROGENASE; CHALCONE DERIVATIVE; FLAVONOID; G PROTEIN COUPLED RECEPTOR; HALOGEN; UNCLASSIFIED DRUG; VIRUS ASSOCIATED RECEPTOR; VIRUS RECEPTOR;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; NONHUMAN; SIGNAL TRANSDUCTION;

ANIMALS; ANTIVIRAL AGENTS; CHO CELLS; CRICETINAE; CRICETULUS; CYTOMEGALOVIRUS; DRUG DISCOVERY; DRUG INVERSE AGONISM; FLAVONOIDS; HEK293 CELLS; HUMANS; RECEPTORS, CHEMOKINE; VIRAL PROTEINS;

EID: 84879592007     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4003457     Document Type: Article

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