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Volumn 68, Issue 3, 2005, Pages 124-134

Human cytomegalovirus-inhibitory flavonoids: Studies on antiviral activity and mechanism of action

Author keywords

Antiviral; Baicalein; Cytomegalovirus; Entry; Genistein; Immediate early function

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ANTIVIRUS AGENT; APIGENIN; BAICALEIN; BIOCHANIN A; DAIDZEIN; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; FLAVONOID; FLAVONOL; GALANGIN; GANCICLOVIR; GENISTEIN; IMMEDIATE EARLY PROTEIN; ISOFLAVONE; LUTEOLIN; NARINGENIN; QUERCETIN; VIRUS DNA; VIRUS PROTEIN;

EID: 27744472231     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2005.08.002     Document Type: Article
Times cited : (129)

References (52)
  • 1
    • 0027383287 scopus 로고
    • Plasma concentrations of phyto-oestrogens in Japanese men
    • H. Adlercreutz, H. Markkanen, and S. Watanabe Plasma concentrations of phyto-oestrogens in Japanese men Lancet 342 1993 1209 1210
    • (1993) Lancet , vol.342 , pp. 1209-1210
    • Adlercreutz, H.1    Markkanen, H.2    Watanabe, S.3
  • 4
    • 0004081896 scopus 로고
    • B. Roizman R.J. Whitley C. Lopez Raven Press New York
    • C.A. Alford, and W.J. Britt B. Roizman R.J. Whitley C. Lopez The Human Herpesviruses 1993 Raven Press New York 227 255
    • (1993) The Human Herpesviruses , pp. 227-255
    • Alford, C.A.1    Britt, W.J.2
  • 5
    • 0027057155 scopus 로고
    • Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis
    • M. Amoros, C.M. Simoes, L. Girre, F. Sauvager, and M. Cormier Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis J. Nat. Prod. 55 1992 1732 1740
    • (1992) J. Nat. Prod. , vol.55 , pp. 1732-1740
    • Amoros, M.1    Simoes, C.M.2    Girre, L.3    Sauvager, F.4    Cormier, M.5
  • 6
    • 0037352439 scopus 로고    scopus 로고
    • Quality, efficacy and safety of complementary medicines: Fashions, facts and the future. Part I. Regulation and quality
    • J. Barnes Quality, efficacy and safety of complementary medicines: fashions, facts and the future. Part I. Regulation and quality Br. J. Clin. Pharmacol. 55 2003 226 233
    • (2003) Br. J. Clin. Pharmacol. , vol.55 , pp. 226-233
    • Barnes, J.1
  • 7
    • 0038416708 scopus 로고    scopus 로고
    • Quality, efficacy and safety of complementary medicines: Fashions, facts and the future. Part II: Efficacy and safety
    • J. Barnes Quality, efficacy and safety of complementary medicines: fashions, facts and the future. Part II: Efficacy and safety Br. J. Clin. Pharmacol. 55 2003 331 340
    • (2003) Br. J. Clin. Pharmacol. , vol.55 , pp. 331-340
    • Barnes, J.1
  • 8
    • 0141863402 scopus 로고    scopus 로고
    • Overview of dietary flavonoids: Nomenclature, occurrence and intake
    • G.R. Beecher Overview of dietary flavonoids: nomenclature, occurrence and intake J. Nutr. 133 2003 3248S 3254S
    • (2003) J. Nutr. , vol.133
    • Beecher, G.R.1
  • 9
    • 0033882193 scopus 로고    scopus 로고
    • Role of human cytomegalovirus immediate-early proteins in cell growth control
    • J.P. Castillo, A.D. Yurochko, and T.F. Kowalik Role of human cytomegalovirus immediate-early proteins in cell growth control J. Virol. 74 2000 8028 8037
    • (2000) J. Virol. , vol.74 , pp. 8028-8037
    • Castillo, J.P.1    Yurochko, A.D.2    Kowalik, T.F.3
  • 10
    • 0024543825 scopus 로고
    • Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element
    • J.M. Cherrington, and E.S. Mocarski Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element J. Virol. 63 1989 1435 1440
    • (1989) J. Virol. , vol.63 , pp. 1435-1440
    • Cherrington, J.M.1    Mocarski, E.S.2
  • 11
    • 0041527063 scopus 로고    scopus 로고
    • In vitro antiviral activities of Caesalpinia pulcherrima and its related flavonoids
    • L.C. Chiang, W. Chiang, M.C. Liu, and C.C. Lin In vitro antiviral activities of Caesalpinia pulcherrima and its related flavonoids J. Antimicrob. Chemother. 52 2003 194 198
    • (2003) J. Antimicrob. Chemother. , vol.52 , pp. 194-198
    • Chiang, L.C.1    Chiang, W.2    Liu, M.C.3    Lin, C.C.4
  • 13
    • 0038402879 scopus 로고
    • Immediate-early gene region of human cytomegalovirus trans-activates the promoter of human immunodeficiency virus
    • M.G. Davis, S.C. Kenney, J. Kamine, J.S. Pagano, and E.S. Huang Immediate-early gene region of human cytomegalovirus trans-activates the promoter of human immunodeficiency virus Proc. Natl. Acad. Sci. U.S.A. 84 1987 8642 8946
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 8642-8946
    • Davis, M.G.1    Kenney, S.C.2    Kamine, J.3    Pagano, J.S.4    Huang, E.S.5
  • 14
    • 0031031453 scopus 로고    scopus 로고
    • Human cytomegalovirus infection inhibits G1/S transition
    • D. Dittmer, and E.S. Mocarski Human cytomegalovirus infection inhibits G1/S transition J. Virol. 71 1997 1629 1634
    • (1997) J. Virol. , vol.71 , pp. 1629-1634
    • Dittmer, D.1    Mocarski, E.S.2
  • 15
    • 4544287124 scopus 로고    scopus 로고
    • Cellular stress and signal transduction responses to human cytomegalovirus infection
    • D.L. Evers, X. Wang, and E.S. Huang Cellular stress and signal transduction responses to human cytomegalovirus infection Microbes Infect 6 2004 1084 1093
    • (2004) Microbes Infect , vol.6 , pp. 1084-1093
    • Evers, D.L.1    Wang, X.2    Huang, E.S.3
  • 16
    • 0029610477 scopus 로고
    • Review of the biology of Quercetin and related bioflavonoids
    • J.V. Formica, and W. Regelson Review of the biology of Quercetin and related bioflavonoids Food Chem. Toxicol. 33 1995 1061 1080
    • (1995) Food Chem. Toxicol. , vol.33 , pp. 1061-1080
    • Formica, J.V.1    Regelson, W.2
  • 17
    • 0022600010 scopus 로고
    • Anti-inflammatory and anti-allergic properties of flavonoids
    • M. Gabor Anti-inflammatory and anti-allergic properties of flavonoids Prog. Clin. Biol. Res. 213 1986 471 480
    • (1986) Prog. Clin. Biol. Res. , vol.213 , pp. 471-480
    • Gabor, M.1
  • 18
    • 0024576835 scopus 로고
    • Detection of cytomegalovirus from clinical specimens in centrifugation culture by in situ DNA hybridization and monoclonal antibody staining
    • C.A. Gleaves, D.A. Hursh, D.H. Rice, and J.D. Meyers Detection of cytomegalovirus from clinical specimens in centrifugation culture by in situ DNA hybridization and monoclonal antibody staining J. Clin. Microbiol. 27 1989 21 23
    • (1989) J. Clin. Microbiol. , vol.27 , pp. 21-23
    • Gleaves, C.A.1    Hursh, D.A.2    Rice, D.H.3    Meyers, J.D.4
  • 19
    • 0036172708 scopus 로고    scopus 로고
    • The 2001 Garrod lecture. the treatment of cytomegalovirus infection
    • P.D. Griffiths The 2001 Garrod lecture. The treatment of cytomegalovirus infection J. Antimicrob. Chemother. 49 2002 243 253
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 243-253
    • Griffiths, P.D.1
  • 20
    • 0030832482 scopus 로고    scopus 로고
    • Antiviral activity of 5,6,7-trimethoxyflavone and its potentiation of the antiherpes activity of acyclovir
    • K. Hayashi, T. Hayashi, H. Otsuka, and Y. Takeda Antiviral activity of 5,6,7-trimethoxyflavone and its potentiation of the antiherpes activity of acyclovir J. Antimicrob. Chemother. 39 1997 821 824
    • (1997) J. Antimicrob. Chemother. , vol.39 , pp. 821-824
    • Hayashi, K.1    Hayashi, T.2    Otsuka, H.3    Takeda, Y.4
  • 21
    • 0026598886 scopus 로고
    • Characterization of human cytomegalovirus UL84 early gene and identification of its putative protein product
    • Y.S. He, L. Xu, and E.S. Huang Characterization of human cytomegalovirus UL84 early gene and identification of its putative protein product J. Virol. 66 1992 1098 1108
    • (1992) J. Virol. , vol.66 , pp. 1098-1108
    • He, Y.S.1    Xu, L.2    Huang, E.S.3
  • 22
    • 0030222284 scopus 로고    scopus 로고
    • A rapid assay for determination of antiviral activity against human cytomegalovirus
    • P.J. Hippenmeyer, and V.M. Dilworth A rapid assay for determination of antiviral activity against human cytomegalovirus Antiviral Res. 32 1996 35 42
    • (1996) Antiviral Res. , vol.32 , pp. 35-42
    • Hippenmeyer, P.J.1    Dilworth, V.M.2
  • 23
    • 0027401895 scopus 로고
    • Centrifugal enhancement of human immunodeficiency virus type 1 infection and human cytomegalovirus gene expression in human primary monocyte/macrophages in vitro
    • W.Z. Ho, R. Cherukuri, S.D. Ge, J.R. Cutilli, L. Song, S. Whitko, and S.D. Douglas Centrifugal enhancement of human immunodeficiency virus type 1 infection and human cytomegalovirus gene expression in human primary monocyte/macrophages in vitro J. Leukoc. Biol. 53 1993 208 212
    • (1993) J. Leukoc. Biol. , vol.53 , pp. 208-212
    • Ho, W.Z.1    Cherukuri, R.2    Ge, S.D.3    Cutilli, J.R.4    Song, L.5    Whitko, S.6    Douglas, S.D.7
  • 24
    • 0015748538 scopus 로고
    • Human cytomegalovirus. I. Purification and characterization of viral DNA
    • E.S. Huang, S.T. Chen, and J.S. Pagano Human cytomegalovirus. I. Purification and characterization of viral DNA J. Virol. 12 1973 1473 1481
    • (1973) J. Virol. , vol.12 , pp. 1473-1481
    • Huang, E.S.1    Chen, S.T.2    Pagano, J.S.3
  • 25
    • 0028862930 scopus 로고
    • Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest
    • F.M. Jault, J.M. Jault, F. Ruchti, E.A. Fortunato, C. Clark, J. Corbeil, D.D. Richman, and D.H. Spector Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest J. Virol. 69 1995 6697 6704
    • (1995) J. Virol. , vol.69 , pp. 6697-6704
    • Jault, F.M.1    Jault, J.M.2    Ruchti, F.3    Fortunato, E.A.4    Clark, C.5    Corbeil, J.6    Richman, D.D.7    Spector, D.H.8
  • 26
    • 0033009115 scopus 로고    scopus 로고
    • Inhibitory effect of 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl) 1H - Imidazole on HCMV DNA replication and permissive infection
    • R.A. Johnson, S.M. Huong, and E.S. Huang Inhibitory effect of 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H - imidazole on HCMV DNA replication and permissive infection Antiviral Res. 41 1999 101 111
    • (1999) Antiviral Res. , vol.41 , pp. 101-111
    • Johnson, R.A.1    Huong, S.M.2    Huang, E.S.3
  • 27
    • 0027978726 scopus 로고
    • Productive infection of human endometrial stromal cells by human cytomegalovirus
    • T.F. Kowalik, A.D. Yurochko, C.A. Rinehart, C.Y. Lee, and E.S. Huang Productive infection of human endometrial stromal cells by human cytomegalovirus Virology 202 1994 247 257
    • (1994) Virology , vol.202 , pp. 247-257
    • Kowalik, T.F.1    Yurochko, A.D.2    Rinehart, C.A.3    Lee, C.Y.4    Huang, E.S.5
  • 30
    • 0020573744 scopus 로고
    • Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on human cytomegalovirus replication in vitro
    • E.C. Mar, Y.C. Cheng, and E.S. Huang Effect of 9-(1,3-dihydroxy-2- propoxymethyl)guanine on human cytomegalovirus replication in vitro Antimicrob. Agents Chemother. 24 1983 518 521
    • (1983) Antimicrob. Agents Chemother. , vol.24 , pp. 518-521
    • Mar, E.C.1    Cheng, Y.C.2    Huang, E.S.3
  • 31
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • E. Middleton Jr., C. Kandaswami, and T.C. Theoharides The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer Pharmacol. Rev. 52 2000 673 751
    • (2000) Pharmacol. Rev. , vol.52 , pp. 673-751
    • Middleton Jr., E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 32
    • 0034048074 scopus 로고    scopus 로고
    • Evaluation of the antiviral activity of kaempferol and its glycosides against human cytomegalovirus
    • D. Mitrocotsa, S. Mitaku, S. Axarlis, C. Harvala, and M. Malamas Evaluation of the antiviral activity of kaempferol and its glycosides against human cytomegalovirus Planta Med. 66 2000 377 379
    • (2000) Planta Med. , vol.66 , pp. 377-379
    • Mitrocotsa, D.1    Mitaku, S.2    Axarlis, S.3    Harvala, C.4    Malamas, M.5
  • 33
    • 0027967730 scopus 로고
    • Human cytomegalovirus elevates levels of the cellular protein p53 in infected fibroblasts
    • P. Muganda, O. Mendoza, J. Hernandez, and Q. Qian Human cytomegalovirus elevates levels of the cellular protein p53 in infected fibroblasts J. Virol. 68 1994 8028 8034
    • (1994) J. Virol. , vol.68 , pp. 8028-8034
    • Muganda, P.1    Mendoza, O.2    Hernandez, J.3    Qian, Q.4
  • 34
    • 0030820932 scopus 로고    scopus 로고
    • Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins
    • S. Pajovic, E.L. Wong, A.R. Black, and J.C. Azizkhan Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins Mol. Cell Biol. 17 1997 6459 6464
    • (1997) Mol. Cell Biol. , vol.17 , pp. 6459-6464
    • Pajovic, S.1    Wong, E.L.2    Black, A.R.3    Azizkhan, J.C.4
  • 35
    • 0025304011 scopus 로고
    • A microtiter virus yield reduction assay for the evaluation of antiviral compounds against human cytomegalovirus and herpes simplex virus
    • M.N. Prichard, S.R. Turk, L.A. Coleman, S.L. Engelhardt, C. Shipman Jr., and J.C. Drach A microtiter virus yield reduction assay for the evaluation of antiviral compounds against human cytomegalovirus and herpes simplex virus J. Virol. Methods 28 1990 101 106
    • (1990) J. Virol. Methods , vol.28 , pp. 101-106
    • Prichard, M.N.1    Turk, S.R.2    Coleman, L.A.3    Engelhardt, S.L.4    Shipman Jr., C.5    Drach, J.C.6
  • 37
    • 0024803247 scopus 로고
    • NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation
    • L.C. Sambucetti, J.M. Cherrington, G.W. Wilkinson, and E.S. Mocarski NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation EMBO J. 8 1989 4251 4258
    • (1989) EMBO J. , vol.8 , pp. 4251-4258
    • Sambucetti, L.C.1    Cherrington, J.M.2    Wilkinson, G.W.3    Mocarski, E.S.4
  • 38
    • 0020429373 scopus 로고
    • Selective inhibition of platelet lipoxygenase by baicalein
    • K. Sekiya, and H. Okuda Selective inhibition of platelet lipoxygenase by baicalein Biochem. Biophys. Res. Commun. 105 1982 1090 1095
    • (1982) Biochem. Biophys. Res. Commun. , vol.105 , pp. 1090-1095
    • Sekiya, K.1    Okuda, H.2
  • 39
    • 0035656189 scopus 로고    scopus 로고
    • Regulation of c-fos induction in lens epithelial cells by 12(S)HETE-dependent activation of PKC
    • R.K. Seth, M.S. Haque, and P.S. Zelenka Regulation of c-fos induction in lens epithelial cells by 12(S)HETE-dependent activation of PKC Invest Ophthalmol. Vis. Sci. 42 2001 3239 3246
    • (2001) Invest Ophthalmol. Vis. Sci. , vol.42 , pp. 3239-3246
    • Seth, R.K.1    Haque, M.S.2    Zelenka, P.S.3
  • 41
    • 0023425999 scopus 로고
    • Insertion and deletion mutagenesis of the human cytomegalovirus genome
    • R.R. Spaete, and E.S. Mocarski Insertion and deletion mutagenesis of the human cytomegalovirus genome Proc. Natl. Acad. Sci. U.S.A. 84 1987 7213 7217
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 7213-7217
    • Spaete, R.R.1    Mocarski, E.S.2
  • 42
    • 0028033418 scopus 로고
    • Potential role of human cytomegalovirus and p53 interaction in coronary restenosis
    • E. Speir, R. Modali, E.S. Huang, M.B. Leon, F. Shawl, T. Finkel, and S.E. Epstein Potential role of human cytomegalovirus and p53 interaction in coronary restenosis Science 265 1994 391 394
    • (1994) Science , vol.265 , pp. 391-394
    • Speir, E.1    Modali, R.2    Huang, E.S.3    Leon, M.B.4    Shawl, F.5    Finkel, T.6    Epstein, S.E.7
  • 44
    • 0042265526 scopus 로고    scopus 로고
    • Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus
    • X. Wang, S.M. Huong, M.L. Chiu, N. Raab-Traub, and E.S. Huang Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus Nature 424 2003 456 461
    • (2003) Nature , vol.424 , pp. 456-461
    • Wang, X.1    Huong, S.M.2    Chiu, M.L.3    Raab-Traub, N.4    Huang, E.S.5
  • 46
    • 0024578841 scopus 로고
    • New soluble-formazan assay for HIV-1 cytopathic effects: Application to high-flux screening of synthetic and natural products for AIDS-antiviral activity
    • O.S. Weislow, R. Kiser, D.L. Fine, J. Bader, R.H. Shoemaker, and M.R. Boyd New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity J. Natl. Cancer Inst. 81 1989 577 586
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 577-586
    • Weislow, O.S.1    Kiser, R.2    Fine, D.L.3    Bader, J.4    Shoemaker, R.H.5    Boyd, M.R.6
  • 47
    • 0032867493 scopus 로고    scopus 로고
    • Human cytomegalovirus 86-kilodalton IE2 protein blocks cell cycle progression in G(1)
    • L. Wiebusch, and C. Hagemeier Human cytomegalovirus 86-kilodalton IE2 protein blocks cell cycle progression in G(1) J. Virol. 73 1999 9274 9283
    • (1999) J. Virol. , vol.73 , pp. 9274-9283
    • Wiebusch, L.1    Hagemeier, C.2
  • 48
    • 0029888987 scopus 로고    scopus 로고
    • The human cytomegalovirus UL94 open reading frame encodes a conserved herpesvirus capsid/tegument-associated virion protein that is expressed with true late kinetics
    • B.A. Wing, G.C. Lee, and E.S. Huang The human cytomegalovirus UL94 open reading frame encodes a conserved herpesvirus capsid/tegument-associated virion protein that is expressed with true late kinetics J. Virol. 70 1996 3339 3345
    • (1996) J. Virol. , vol.70 , pp. 3339-3345
    • Wing, B.A.1    Lee, G.C.2    Huang, E.S.3
  • 50
    • 0030994219 scopus 로고    scopus 로고
    • The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection
    • A.D. Yurochko, E.S. Hwang, L. Rasmussen, S. Keay, L. Pereira, and E.S. Huang The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection J. Virol. 71 1997 5051 5059
    • (1997) J. Virol. , vol.71 , pp. 5051-5059
    • Yurochko, A.D.1    Hwang, E.S.2    Rasmussen, L.3    Keay, S.4    Pereira, L.5    Huang, E.S.6
  • 51
    • 0029093580 scopus 로고
    • Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters
    • A.D. Yurochko, T.F. Kowalik, S.M. Huong, and E.S. Huang Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters J. Virol. 69 1995 5391 5400
    • (1995) J. Virol. , vol.69 , pp. 5391-5400
    • Yurochko, A.D.1    Kowalik, T.F.2    Huong, S.M.3    Huang, E.S.4
  • 52
    • 0030947410 scopus 로고    scopus 로고
    • Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters
    • A.D. Yurochko, M.W. Mayo, E.E. Poma, A.S. Baldwin Jr., and E.S. Huang Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters J. Virol. 71 1997 4638 4648
    • (1997) J. Virol. , vol.71 , pp. 4638-4648
    • Yurochko, A.D.1    Mayo, M.W.2    Poma, E.E.3    Baldwin Jr., A.S.4    Huang, E.S.5


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