Selective determination of potential impurities in an active pharmaceutical ingredient using HPLC-SPE-HPLC

Journal of Pharmaceutical and Biomedical Analysis

Volumn 84, Issue , 2013, Pages 41-47

  Yamamoto, Eiichi ^a   Niijima, Jun ^a   Asakawa, Naoki ^a  

^a EISAI CO LTD   (Japan)

Author keywords

Impurity; Multi dimensional HPLC; Selective determination; Solid phase extraction; Synthetic intermediate

Indexed keywords

DIMETHYL SULFOXIDE;

ACCURACY; ARTICLE; DRUG DETERMINATION; DRUG IMPURITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF QUANTITATION; PRIORITY JOURNAL; SEPARATION TECHNIQUE; SOLID PHASE EXTRACTION;

IMPURITY; MULTI-DIMENSIONAL HPLC; SELECTIVE DETERMINATION; SOLID-PHASE EXTRACTION; SYNTHETIC INTERMEDIATE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; PHARMACEUTICAL PREPARATIONS; SOLID PHASE EXTRACTION;

EID: 84879559442     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.05.033     Document Type: Article

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