Analysis of pyramidal neuron morphology in an inducible knockout of brain-derived neurotrophic factor

Biological Psychiatry

Volumn 57, Issue 8, 2005, Pages 932-934

  Hill, Justin J ^a   Kolluri, Nutan ^a   Hashimoto, Takanori ^a   Wu, Qiang ^b   Sampson, Allan R ^b   Monteggia, Lisa M ^c   Lewis, David A ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

BDNF; Dendritic spine; Inducible knockout; Prefrontal cortex; Pyramidal neuron; Schizophrenia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CINGULATE GYRUS; COMPARATIVE STUDY; CONTROLLED STUDY; DENDRITIC CELL; DENSITY; EMBRYO DEVELOPMENT; GENE EXPRESSION; GOLGI COMPLEX; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; QUANTITATIVE ANALYSIS; SCHIZOPHRENIA; SPINE; WILD TYPE;

EID: 16844385099     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2005.01.010     Document Type: Article

References (19)

1. S.A. Anderson, J.D. Classey, F. Condé, J.S. Lund, D.A. Lewis Synchronous development of pyramidal neuron dendritic spines and parvalbumin-immunoreactive chandelier neuron axon terminals in layer III of monkey prefrontal cortex Neuroscience 67 1995 7 22
2. G.N. Elston Pyramidal cells of the frontal lobe All the more spinous to think with J Neurosci 20 2000 RC95
3. L.J. Garey, W.Y. Ong, T.S. Patel, M. Kanani, A. Davis, A.M. Mortimer Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia J Neurol Neurosurg Psychiatry 65 1998 446 453
4. C. Genoud, G.W. Knott, K. Sakata, B. Lu, E. Welker Altered synapse formation in the adult somatosensory cortex of brain-derived neurotrophic factor heterozygote mice J Neurosci 24 2004 2394 2400
5. L.A. Glantz, D.A. Lewis Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia Arch Gen Psychiatry 57 2000 65 73
6. K.M. Harmon, C.L. Wellman Differential effects of cholinergic lesions on dendritic spines in frontal cortex of young adult and aging rats Brain Res 992 2003 60 68
7. T. Hashimoto, S. Bergen, Q.L. Nguyen, B. Xu, L.M. Monteggia, J.N. Pierri Relationship of brain-derived neurotrophic factor and its receptor trkB to altered inhibitory prefrontal circuitry in schizophrenia in press J Neurosci 25 2005 372 383
8. T.L. Hayes, D.A. Lewis Hemispheric differences in layer III pyramidal neurons of the anterior language areas Arch Neurol 50 1993 501 505
9. T.L. Hayes, D.A. Lewis Magnopyramidal neurons in the anterior motor speech region Dendritic features and interhemispheric comparisons Arch Neurol 53 1996 1277 1283
10. R.C. Littell, G.A. Milliken, W.W. Stroup, R.D. Wolfinger SAS System for Mixed Models 1996 SAS Institute Cary, North Carolina
11. J.S. Lund Organization of neurons in the visual cortex, area 17, of the monkey (macaca mulatta) J Comp Neurol 147 1973 455 496
12. A.K. McAllister, L.C. Katz, D.C. Lo Neurotrophin regulation of cortical dendritic growth requires activity Neuron 17 1996 1057 1064
13. A.K. McAllister, D.C. Lo, L.C. Katz Neurotrophins regulate dendritic growth and developing visual cortex Neuron 15 1995 791 803
14. L.M. Monteggia, M. Barrot, C.M. Powell, O. Berton, V. Galanis, T. Gemelli Essential role of brain-derived neurotrophic factor in adult hippocampal function Proc Natl Acad Sci U S A 101 2004 10827 10832
15. G. Paxinos, K. Franklin The Mouse Brain in Stereotaxic Coordinates 2nd ed 2001 Academic Press San Diego
16. J.N. Pierri, C.L.E. Volk, S. Auh, A. Sampson, D.A. Lewis Decreased somal size of deep layer 3 pyramidal neurons in the prefrontal cortex in subjects with schizophrenia Arch Gen Psychiatry 58 2001 466 473
17. G. Rajkowska, L.D. Selemon, P.S. Goldman-Rakic Neuronal and glial somal size in the prefrontal cortex A postmortem morphometric study of schizophrenia and Huntington disease Arch Gen Psychiatry 55 1998 215 224
18. G.W. Snedecor, W.G. Cochran Statistical Methods 7th ed 1980 Iowa State University Press Ames, Iowa
19. C.S. Weickert, T.M. Hyde, B.K. Lipska, M.M. Herman, D.R. Weinberger, J.E. Kleinman Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia Mol Psychiatry 8 2003 592 610