Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury

European Heart Journal

Volumn 34, Issue 24, 2013, Pages 1834-1845

  Pu, Jun ^a   Yuan, Ancai ^a   Shan, Peiren ^a   Gao, Erhe ^b   Wang, Xiaoliang ^b   Wang, Yajing ^b   Lau, Wayne Bond ^b   Koch, Walter ^b   Ma, Xin Liang ^b   He, Ben ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Apoptosis; Myocytes; Nuclear receptors

Indexed keywords

CASPASE 12; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; FARNESOID X RECEPTOR; MESSENGER RNA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL ISOLATION; CELL VIABILITY; CELLULAR DISTRIBUTION; DOSE RESPONSE; ENZYME ACTIVATION; FIBROBLAST; GENE SILENCING; HEART; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; MYOCYTES; NUCLEAR RECEPTORS;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELL SURVIVAL; CHENODEOXYCHOLIC ACID; CYCLOSPORINE; CYTOCHROMES C; ENZYME INHIBITORS; ISOXAZOLES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PREGNENEDIONES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, SMALL INTERFERING;

EID: 84879510808     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehs011     Document Type: Article

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