Osteopontin: Participation in inflammation or mucosal protection in inflammatory bowel diseases?

Digestive Diseases and Sciences

Volumn 58, Issue 6, 2013, Pages 1569-1580

  Chen, Fengyuan ^a   Liu, Hongchun ^a   Shen, Qiang ^a   Yuan, Shengzhong ^a   Xu, Lin ^a   Cai, Xunquan ^a   Lian, Jingjing ^a   Chen, Shi Yao ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Immune response; Inflammatory bowel diseases; Mucosal protection; Osteopontin

Indexed keywords

AMINOSALICYLIC ACID; AZATHIOPRINE; BETA ACTIN; GAMMA INTERFERON; INFLIXIMAB; INTERLEUKIN 10; INTERLEUKIN 1BETA; OSTEOPONTIN; SALAZOSULFAPYRIDINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; COLITIS; COLON BIOPSY; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM CELL; LAMINA PROPRIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH MUCOSA; TH1 CELL; ULCERATIVE COLITIS; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; COLITIS, ULCERATIVE; COLON; CROHN DISEASE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; OSTEOPONTIN; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 84879503457     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2556-y     Document Type: Article

References (29)

1. Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS. Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest. 2001;107:1055-1061.
2. Senger DR, Asch BB, Smith BD, Perruzzi CA, Dvorak HF. A secreted phosphoprotein marker for neoplastic transformation of both epithelial and broblastic cells. Nature. 1983;302:714-715.
3. Patarca R, Freeman GJ, Singh RP, et al. Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T-cell-dependent response associated with genetic resistance to bacterial infection. J Exp Med. 1989;170:145-161.
4. Ashkar S, Weber GF, Panoutsakopoulou V, et al. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science. 2000;287:860-864.
5. Chabas D, Baranzini SE, Mitchell D, et al. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science. 2001;294:1731-1735.
6. Sato T, Nakai T, Tamura N, et al. Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response. Gut. 2005;54:1254-1262.
7. Mishima R, Takeshima F, Sawai T, et al. High plasma osteopontin levels in patients with inflammatory bowel disease. J Clin Gastroenterol. 2007;41:167-172.
8. Gassler N, Autschbach F, Gauer S, et al. Expression of osteopontin (Eta-1) in Crohn disease of the terminal ileum. Scand J Gastroenterol. 2002;37:1286-1295.
9. Zhong J, Eckhardt ER, Oz HS, Bruemmer D, de Villiers WJ. Osteopontin deficiency protects mice from dextran sodium sulfate-induced colitis. Inflamm Bowel Dis. 2006;12:790-796.
10. Zohar R, Suzuki N, Suzuki K, et al. Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration. J Cell Physiol. 2000;184:118-130.
11. Zhu B, Suzuki K, Goldberg HA, et al. Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: evidence of a role for an intracellular form of osteopontin. J Cell Physiol. 2004;198:155-167.
12. Brown LF, Berse B, van de Water L, et al. Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces. Mol Biol Cell. 1992;3:1169-1180.
13. Qu-Hong, Dvorak AM. Ultrastructural localization of osteopontin immunoreactivity in phagolysosomes and secretory granules of cells in human intestine. Histochem J. 1997;29:801-812.
14. Da Silva AP, Pollett A, Rittling SR, Denhardt DT, Sodek J, Zohar R. Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-a expression and non-programmed cell death. J Cell Physiol. 2006;208:629-639.
15. Inflammatory Bowel Disease Co-operation Group. Chinese Society of Gastroenterology. Chinese consensus on diagnosis and treatment standard of inflammatory bowel disease. Chin J Gastroenterol. 2007;12:488-495.
16. Cooper HS, Murthy SN, Shan RS, Sedergran DJ. Clinicopathogogic study of dextran sulfate sodium experimental murine colitis. Lab Invest. 1993;69:238-249.
17. Zhang H, Zhang Y. The quantitative analysis on immunohistochemical image of non-small cell lung cancer biology characteristic. Chin J Stereol Image Anal. 2006;11:77-79.
18. Masuda H, Takahashi Y, Asai S, Hemmi A, Takayama T. Osteopontin expression in ulcerative colitis is distinctly different from that in Crohn's disease and diverticulitis. J Gastroenterol. 2005;40:409-413.
19. Chen S, Kaifang Z, Tian Y, Tan Y, Ding Y, Qian W. Expression and significance of toll-like receptor (TLR) 2, TLR4 and TLR9 in colonic mucosa of rat model with induced colitis. Chin J Gastroenterol. 2007;12:339-343.
20. Bruemmer D, Collins AR, Noh G, et al. Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest. 2003;112:1318-1331.
21. Lakatos L. Immunology of inflammatory bowel diseases. Acta Physiol Hung. 2000;87:355-372.
22. Sawa Y, Oshitani N, Adachi K, Higuchi K, Matsumoto T, Arakawa T. Comprehensive analysis of intestinal cytokine messenger RNA profile by real-time quantitative polymerase chain reaction in patients with inflammatory bowel disease. Int J Mol Med. 2003;11:175-179.
23. Dieleman LA, Palmen MJ, Akol H, et al. Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines. Clin Exp Immuol. 1998;114:385-391.
24. Naik S, Kelly EJ, Meijer L, Pettersson S, Sanderson IR. Absence of Toll-like receptor 4 explains endotoxin hyporesponsiveness in human intestinal epithelium. J Pediatr Gastroenterol Nutr. 2001;32:449-453.
25. Melgar S, Yeung MM, Bas A, et al. Over expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis. Clin Exp Immunol. 2003;134:127-137.
26. Xinsheng Yao. Survey and progress of Th1 and Th2. Int J Immunol. 2002;25:290-293.
27. Lindsay JO, Ciesielski CJ, Scheinin T, Brennan FM, Hodgson HJ. Local delivery of adenoviral vectors encoding murine interleukin 10 induces colonic interleukin 10 production and is therapeutic for murine colitis. Gut. 2003;52:363-369.
28. Heilmann K, Hoffmann U, Witte E, et al. Osteopontin as two-sided mediator of intestinal inflammation. J Cell Mol Med. 2009;13:1162-1174.
29. Lund SA, Giachelli CM, Scatena M. The role of osteopontin in inflammatory processes. J Cell Commun Signal. 2009;3:311-322.