Geraniol inhibits murine skin tumorigenesis by modulating COX-2 expression, Ras-ERK1/2 signaling pathway and apoptosis

Journal of Applied Toxicology

Volumn 33, Issue 8, 2013, Pages 828-837

  Chaudhary, Sandeep Chand ^a   Siddiqui, Mohammad Saeed ^a   Athar, Mohammad ^a   Alam, Mohammad Sarwar ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Apoptosis; Geraniol; Inflammation; Oxidative stress; Ras pathway; Skin tumorigenesis

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; CYCLOOXYGENASE 2; GERANIOL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BAX; PROTEIN BCL 2; RAS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INCIDENCE; CANCER INHIBITION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; FEMALE; HYPERPLASIA; LATENT PERIOD; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKIN CARCINOGENESIS; SKIN EDEMA; TOPICAL TREATMENT;

ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOGENESIS; CYCLOOXYGENASE 2; EDEMA; FEMALE; INFLAMMATION; MAP KINASE SIGNALING SYSTEM; MICE; OXIDATIVE STRESS; RAS PROTEINS; SKIN; TERPENES; TETRADECANOYLPHORBOL ACETATE;

MURINAE; MUS;

EID: 84879499218     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2739     Document Type: Article

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