Modulation of inflammation and oxidative stress in canine chondrocytes

American Journal of Veterinary Research

Volumn 74, Issue 7, 2013, Pages 983-989

  Dycus, David L ^a,d   Au, Angela Y ^b   Grzanna, Mark W ^c   Wardlaw, Jennifer L ^a   Frondoza, Carmelita G ^a,c,e  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b Syracuse University   (United States)

^c NUTRAMAX LABORATORIES INC   (United States)

^d Charleston Veterinary Referral Center   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; INTERLEUKIN 1BETA; PROSTAGLANDIN E2; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CONTROLLED STUDY; DOG; HOMEOSTASIS; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE;

ANIMALS; CELLS, CULTURED; CHONDROCYTES; DOGS; GLUTATHIONE; HYDROGEN PEROXIDE; INFLAMMATION; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

CANIS FAMILIARIS;

EID: 84879489679     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.74.7.983     Document Type: Article

References (52)

1. Johnston SA. Osteoarthritis. Joint anatomy, physiology, and pathobiology. Vet Clin North Am Small Anim Pract 1997;27:699-723.
2. Venable RO, Stoker AM, Cook CR, et al. Examination of synovial fluid hyaluronan quantity and quality in stifle joints of dogs with osteoarthritis. Am J Vet Res 2008;69:1569-1573.
3. Prink A, Hayashi K, Kim SY, et al. Evaluation of a collagenase generated osteoarthritis biomarker in the synovial fluid from elbow joints of dogs with medial coronoid disease and unaffected dogs. Vet Surg 2010;39:65-70.
4. Henrotin Y, Kurz B, Aigner T. Oxygen and reactive oxygen species in cartilage degradation: friends or foes? Osteoarthntis Cartilage 2005;13:643-654.
5. Martin G, Andriamanalijaona R, Mathy-Hartert M, et al. Comparative effects of IL-1p and hydrogen peroxide (HO) on cata-bolic and anabolic gene expression in juvenile bovine chondrocytes. Osteoarthritis Cartilage 2005;13:915-924.
6. de Bruin T, de Rooster H, van Bree H, et al. Cytokine mRNA expression in synovial fluid of affected and contralateral stifle joints and the left shoulder joint in dogs with unilateral disease of the stifle joint. Am J Vet Res 2007;68:953-961.
7. Martin G, Andriamanalijaona R, Grassel S, et al. Effect of hypoxia and reoxygenation on gene expression and response to in-terleukin-1 in cultured articular chondrocytes. Arthritis Rheum 2004;50:3549-3560.
8. Mathy-Hartert M, Burton S, Deby-Dupont G, et al. Influence of oxygen tension on nitric oxide and prostaglandin E2 synthesis by bovine chondrocytes Osteoarthritis Cartilage 2005;13:74-79.
9. Yasuhara R, Miyamoto Y, Akaike T, et al. Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner. Biochem J 2005;389:315-323.
10. Burkhardt H, Schwingel M, Menninger H, et al. Oxygen radicals as effectors of cartilage destruction. Direct degradative effect on matrix components and indirect action via activation of latent collagenase from polymorphonuclear leukocytes. Arthritis Rheum 1986;29:379-387.
11. Hiran TS, Moulton PJ, Hancock JT. In situ detection of superoxide anions within porcine articular cartilage. Br J Biomed Sci 1998;55:199-203.
12. Pagoria D, Lee A, Geurtsen W. The effect of camphorquinone (CQ) and CQ-related photosensitizers on the generation of reactive oxygen species and the production of oxidative DNA damage. Biomaterials 2005;26:4091-4099.
13. Shan X, Chang Y, Lin CL. Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression. FASEB J 2007;21:2753-2764.
14. Yudoh K, Nguyen T, Nakamura H, et al. Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function. Arthritis Res Ther 2005;7:R380-R391.
15. Hauschild G, Muschter N, Richter A, et al. Cartilage replacement in dogs-a preliminary investigation of colonization of ceramic matrices. Vet Corny Orthop Traumatol 2009;22:216-221.
16. Falchuk KH, Goetzl EJ, Kulka JP. Respiratory gases of synovial fluids. An approach to synovial tissue circulatory-metabolic imbalance in rheumatoid arthritis. Am J Med 1970;49:223-231.
17. Mathy-Hartert M, Hogge L, Sanchez C, et al. Interleukin-1beta and interleukin-6 disturb the antioxidant enzyme system in bovine chondrocytes: a possible explanation for oxidative stress generation. OstewirthntisCartilage 2008;16:756-763.
18. Brighton CT, Heppenstall RB. Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits. J Bone Joint Surg Am 1971;53:719-728.
19. Rajpurohit R, Koch CJ, Tao Z, et al. Adaptation of chondrocytes to low oxygen tension: relationship between hypoxia and cellular metabolism. J Cell Physiol 1996;168:424-432.
20. Grimshaw MJ, Mason RM. Bovine articular chondrocyte function in vitro depends upon oxygen tension. Osteoarthritis Carti-lage 2000;8:386-392.
21. Clancy RM, Gomez PF, Abramson SB. Nitric oxide sustains nuclear factor kappaB activation in cytokine-stimulated chondrocytes. Osteoarthritis Cartilage 2004;12:552-558.
22. Lo YY, Conquer JA, Grinstein S, et al. Interleukin-1 beta induction of c-fos and collagenase expression in articular chondrocytes: involvement of reactive oxygen species. J Cell Biochem 1998;69:19-29.
23. Huck JL, Biery DN, Lawler DF, et al. A longitudinal study of the influence of lifetime food restriction on development of osteoarthritis in the canine elbow. Vet Surg 2009;38:192-198.
24. Roush JK, Cross AR, Renberg WC, et al. Evaluation of the effects of dietary supplementation with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis. J Am Vet Med Assoc 2010;236:67-73.
25. Roush JK, Dodd CE, Fritsch DA, et al. Multicenter veterinary practice assessment of the effects of omega-3 fatty acids on osteoarthritis in dogs. J Am Vet Med Assoc 2010;236:59-66.
26. Fujiki M, Shineha J, Yamanokuchi K, et al. Effects of treatment with polysulfated glycosaminoglycan on serum cartilage oligo-meric matrix protein and C-reactive protein concentrations, serum matrix metalloproteinase-2 and -9 activities, and lameness in dogs with osteoarthritis. Am J Vet Res 2007;68:827-833.
27. Marshall W, Bockstahler B, Hulse D, et al. A review of osteoarthritis and obesity: current understanding of the relationship and benefit of obesity treatment and prevention in the dog. Vet Comp Orthop Traumatol 2009;22:339-345.
28. Prieto-Sagredo J, Ricalde-Recchia I, Duran-Lizarraga ME, et al. Changes in hemolymph glutathione status after variation in photoperiod and light-irradiance in crayfish Procambarus clarkii and Procambarus digueti. Photochem Photobiol 2000;71:487-492.
29. Heinecke LF, Grzanna MW, Au AY, et al. Inhibition of cyclo-oxygenase-2 expression and prostaglandin E production in chondrocytes by avocado soybean unsaponifiables and epigal-locatechin gallate. Osteoarthntis Cartilage 2010;18:220-227.
30. Frondoza CG, Heinecke LF, Grzanna MW, et al. Modulation of cytokine-induced prostaglandin E production in cultures of articular chondrocytes obtained from carpal joints of camels (Camelus dromedarius). Am J Vet Res 2011;72:51-58.
31. Au RY, Al-Talib TK, Au AY, et al. Avocado soybean unsaponifiables (ASU) suppress TNF-a, IL-1fS, COX-2, iNOS gene expression, and prostaglandin E, and nitric oxide production in articular chondrocytes and monocyte/macrophages. Osteoarthritis Cartilage 2007;15:1249-1255.
32. Davies CM, Guilak F, Weinberg JB, et al. Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis. Osteoailhntis Cartilage 2008;16:624-630.
33. Lee S, Pagoria D, Raigrodski A, et al. Effects of combinations of ROS scavengers on oxidative DNA damage caused by visible-light-activated camphorquinone/N,N-dimethyl-p-toluidine. J Biomed Mater Res B Awl Biomater 2007;83:391-399.
34. Amin AR, Attur M, Patel RN, et al. Superinduction of cyclo-oxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide. J Clin Invest 1997;99:1231-1237.
35. Alvarez-Soria MA, Largo R, Sanchez-Pernaute O, et al. Prostaglandin E receptors EP1 and EP4 are up-regulated in rabbit chondrocytes by IL-1beta, but not by TNFalpha. Rheumatol Int 2007;27:911-917.
36. Geng Y, Blanco FJ, Cornelisson M, et al. Regulation of cyclooxy-genase-2 expression in normal human articular chondrocytes. J Immunol 1995;155:796-801.
37. Palmer RM, Hickery MS, Charles IG, et al. Induction of nitric oxide synthase in human chondrocytes. Biochem Biophys Res Commun 1993;193:398-405.
38. Aigner T, Fundel K, Saas J, et al. Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis. Arthritis Rheum 2006;54:3533-3544.
39. Sharma V, Mishra M, Ghosh S, et al. Modulation of interleukin-1beta mediated inflammatory response in human astrocytes by flavonoids: implications in neuroprotection. Brain Res Bull 2007;73:55-63.
40. Scott JL, Gabrielides C, Davidson RK, et al. Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease [Erratum published in Ann Rheum Dis 2011;70:397]. Ann Rheum Dis 2010;69:1502-1510.
41. Afonso V, Santos G, Collin P, et al. Tumor necrosis factor-alpha down-regulates human Cu/Zn superoxide dismutase 1 promoter via JNK/AP-1 signaling pathway. Free Radic Biol Med 2006;41:709-721.
42. Kiningham KK, Xu Y, Daosukho C, et al. Nuclear factor kappaB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2. Bio-chem J 2001;353:147-156.
43. Henrotin YE, Bruckner P, Pujol JP The role of reactive oxygen species in homeostasis and degradation of cartilage. Osteoarthritis Cartilage 2003;11:747-755.
44. Ruiz-Romero C, Calamia V, Mateos J, et al. Mitochondrial dysregu-lation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance. Mol Cell Proteomics 2009;8:172-189.
45. Regan E, Flannelly J, Bowler R, et al. Extracellular superoxide dismutase and oxidant damage in osteoarthritis. Arthritis Rheum 2005;52:3479-3491.
46. Wendell PL. Measurement of oxidized glutathione and total glutathione in the perfused rat heart. Biochem J 1970;117:661-665.
47. Carlo MD Jr, Loeser RF. Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels. Arthritis Rheum 2003;48:3419-3430.
48. Bazzichi L, Ciompi ML, Betti L, et al. Impaired glutathione reductase activity and levels of collagenase and elastase in synovial fluid in rheumatoid arthritis. Clin Exp Rheumatol 2002;20:761-766.
49. Ghibelli L, Fanelli C, Rotilio G, et al. Rescue of cells from apoptosis by inhibition of active GSH extrusion. FASEB J 1998;12:479-486.
50. Baker MS, Feigan J, Lowther DA. Chondrocyte antioxidant defences: the roles of catalase and glutathione peroxidase in protection against HO dependent inhibition of proteoglycan biosynthesis. JRheumatol 1988;15:670-677.
51. Bates EJ, Lowther DA, Johnson CC. Hyaluronic acid synthesis in articular cartilage: an inhibition by hydrogen peroxide. Biochem Biophys Res Commun 1985;132:714-720.
52. Ueno T, Yamada M, Sugita Y, et al. N-acetyl cysteine protects TMJ chondrocytes from oxidative stress. J Dent Res 2011;90:353-359.