Aldosterone regulates Na+, K+ ATPase activity in human renal proximal tubule cells through mineralocorticoid receptor

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 10, 2013, Pages 2143-2152

  Salyer, Sarah A ^a   Parks, Jason ^a   Barati, Michelle T ^a   Lederer, Eleanor D ^a,b   Clark, Barbara J ^c   Klein, Janet D ^d   Khundmiri, Syed J ^a,b  

^a University of Louisville School of Medicine   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF LOUISVILLE   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aldosterone; K+ ATPase; Mineralocorticoid receptor; Na+; Proximal tubule; Sodium and glucocorticoid dependent kinase

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AGGLUTININ; ALDOSTERONE; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE; MINERALOCORTICOID RECEPTOR; RUBIDIUM 86; SODIUM PHOSPHATE COTRANSPORTER; SPIRONOLACTONE;

ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LINE; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY PROXIMAL TUBULE; LOTUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; STAINING;

ALDOSTERONE; K(+) ATPASE; MINERALOCORTICOID RECEPTOR; NA(+); PROXIMAL TUBULE; SODIUM AND GLUCOCORTICOID-DEPENDENT KINASE;

ADENOSINE TRIPHOSPHATE; ALDOSTERONE; ANIMALS; BLOTTING, WESTERN; CELL MEMBRANE; CELLS, CULTURED; HUMANS; HYDROLYSIS; IMMUNOENZYME TECHNIQUES; KIDNEY TUBULES, PROXIMAL; MALE; MICE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MINERALOCORTICOID; SODIUM-POTASSIUM-EXCHANGING ATPASE;

LOTUS TETRAGONOLOBUS; RATTUS;

EID: 84879489648     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.05.009     Document Type: Article

References (46)

1. Edelman I.S., Fimognari G.M. On the biochemical mechanism of action of aldosterone. Recent Prog. Horm. Res. 1968, 24:1-44.
2. Foster R.H., MacFarlane C.H., Bustamante M.O. Recent progress in understanding aldosterone secretion. Gen. Pharmacol. 1997, 28:647-651.
3. Fuller P.J. Aldosterone's effects and mechanism of action. Curr. Opin. Endocrinol. Diabetes 1997, 4:218-224.
4. Luetscher J.A., Neher J.P., Wettstein A. Isolation of crystalline aldosterone from the urine of a nephrotic patient. Experientia 1954, 10:456-458.
5. Rossier B.C. Mechanisms of action of mineralocorticoid hormones. Endocr. Res. 1989, 15:206-226.
6. Hierholzer K., Stolte H. The proximal and distal tubular action of adrenal steroids on Na reabsorption. Nephron 1969, 6:188-204.
7. Wiederholt M., Stolte H., Brecht J.P., Hierholzer K. Micropuncture research on the effect of aldosterone, cortisone and dexamethasone on renal sodium resorption in adrenalectomized rats. Pflugers Arch. Gesamte Physiol. Menschen Tiere 1966, 292:316-333.
8. Fernández-Llama P., Ageloff S., Fernández-Varo G., Ros J., Wang X., Arra N., Esteva-Font C., Ballarin J., Barcelo P., Arroyo V., Stokes J.B., Knepper M.A., Jiménez W. Sodium retention in cirrhotic rats is associated with increased renal abundance of sodium transporter proteins. Kidney Int. 2005, 67:622-630.
9. Drumm K., Kress T.R., Gassner B., Krug A.W., Gekle M. Aldosterone stimulates activity and surface expression of NHE3 in human primary proximal tubule epithelial cells (RPTEC). Cell. Physiol. Biochem. 2006, 17:21-28.
10. Krug A.W., Papavassiliou F., Hopfer U., Ullrich K.J., Gekle M. Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders. Pflugers Arch. 2003, 446:492-496.
11. Pinto V., Pinho M.J., Hopfer U., Jose P.A., Soares-da-Silva P. Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells. Mol. Cell. Biochem. 2008, 310:191-201.
12. +-ATPase in proximal S3 segments. Am. J. Physiol. Renal Physiol. 2011, 300:F682-F691.
13. Pergher P.S., Leite-Dellova D., de Mello-Aires M. Direct action of aldosterone on bicarbonate reabsorption in in vivo cortical proximal tubule. Am. J Physiol. Renal Physiol. 2009, 296:F1185-F1193.
14. + exchanger 3 in the mammalian kidney. Am. J Physiol. Renal Physiol. 2010, 299:F1496-F1506.
15. Saad S., Stevens V.A., Wassef L., Poronnik P., Kelly D.J., Gilbert R.E., Pollock C.A. High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule. Kidney Int. 2005, 68:985-997.
16. Stevens V.A., Saad S., Poronnik P., Fenton-Lee C.A., Polhill T.S., Pollock C.A. The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells. Nephrol. Dial. Transplant. 2008, 23:1834-1843.
17. Bujalska I., Shimojo M., Howie A., Stewart P.M. Human 11 beta-hydroxysteroid dehydrogenase: studies on the stably transfected isoforms and localization of the type 2 isozyme within renal tissue. Steroids 1997, 62:77-82.
18. Kyossev Z., Walker P.D., Reeves W.B. Immunolocalization of NAD-dependent 11 beta-hydroxysteroid dehydrogenase in human kidney and colon. Kidney Int. 1996, 49:271-281.
19. McKinnell J., Roscoe D., Holmes M.C., Lloyd-MacGilp S.A., Kenyon C.J. Regulation of 11beta-hydroxysteroid dehydrogenase enzymes by dietary sodium in the rat. Endocr. Res. 2000, 26:81-95.
20. Bonvalet J.P., Doignon I., Blot-Chabaud M., Pradelles P., Farman N. Distribution of 11 beta-hydroxysteroid dehydrogenase along the rabbit nephron. J. Clin. Invest. 1990, 86:832-837.
21. Naruse M., Klein J.D., Ashkar Z.M., Jacobs J.D., Sands J.M. Glucocorticoids downregulate the rat vasopressin-regulated urea transporter in rat terminal inner medullary collecting ducts. J. Am. Soc. Nephrol. 1997, 8:517-523.
22. Holthouser K.A., Mandal A., Merchant M.L., Schelling J.R., Delamere N.A., Valdes R.R., Tyagi S.C., Lederer E.D., Khundmiri S.J. Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells. Am. J. Physiol. Renal Physiol. 2010, 299:F77-F90.
23. Sacktor B., Rosenbloom I.L., Liang C.T., Cheng L. Sodium gradient- and sodium plus potassium gradient-dependent l-glutamate uptake in renal basolateral membrane vesicles. J. Membr. Biol. 1981, 60:63-71.
24. Khundmiri S.J., Amin V., Henson J., Lewis J., Ameen M., Rane M.J., Delamere N.A. Ouabain stimulates protein kinase B (Akt) phosphorylation in opossum kidney proximal tubule cells through an ERK-dependent pathway. Am. J. Physiol. Cell Physiol. 2007, 293:C1171-C1180.
25. Khundmiri S.J., Metzler M.A., Ameen M., Amin V., Rane M.J., Delamere N.A. Ouabain induces cell proliferation through calcium-dependent phosphorylation of Akt (protein kinase B) in opossum kidney proximal tubule cells. Am. J. Physiol. Cell Physiol. 2006, 291:C1247-C1257.
26. Khundmiri S.J., Asghar M., Banday A.A., Khan F., Salim S., Levi M., Yusufi A.N. Effect of ischemia reperfusion on sodium-dependent phosphate transport in renal brush border membranes. Biochim. Biophys. Acta 2005, 1716:19-28.
27. Seok J.H., Hong J.H., Jeon J.R., Hur G.M., Sung J.Y., Lee J.H. Aldosterone directly induces Na, K-ATPase alpha 1-subunit mRNA in the renal cortex of rat. Biochem. Mol. Biol. Int. 1999, 47:251-254.
28. Seok J.H., Kim J.B., Hong J.H., Hur G.M., Jeon J.R., Lim K., Hwang B.D., Lee J.H. Aldosterone stimulates Na,K-ATPase activity in basolateral membrane of rat kidney. Biochem. Mol. Biol. Int. 1998, 45:879-885.
29. Braga-Sobrinho C., Leite-Dellova D.C., Mello-Aires M. Action of ANP on the nongenomic dose-dependent biphasic effect of aldosterone on NHE1 in proximal S3 segment. J. Steroid Biochem. Mol. Biol. 2012, 128:89-97.
30. Racusen L.C., Monteil C., Sgrignoli A., Lucskay M., Marouillat S., Rhim J.G., Morin J.P. Cell lines with extended in vitro growth potential from human renal proximal tubule: characterization, response to inducers, and comparison with established cell lines. J. Lab. Clin. Med. 1997, 129:318-329.
31. + exchanger in proximal S3 segment: role of cytosolic calcium. Am. J. Physiol. Renal Physiol. 2008, 295:F1342-F1352.
32. Ackermann D., Gresko N., Carrel M., Loffing-Cueni D., Habermehl D., Gomez-Sanchez C., Rossier B.C., Loffing J. In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule. Am. J. Physiol. Renal Physiol. 2010, 299:F1473-F1485.
33. El Mernissi G., Doucet A. Short-term effects of aldosterone and dexamethasone on Na-K-ATPase along the rabbit nephron. Pflugers Arch. 1983, 399:147-151.
34. Mujais S.K., Chekal M.A., Jones W.J., Hayslett J.P., Katz A.I. Modulation of renal sodium-potassium-adenosine triphosphatase by aldosterone. Effect of high physiologic levels on enzyme activity in isolated rat and rabbit tubules. J. Clin. Invest. 1985, 76:170-176.
35. Blot-Chabaud M., Djelidi S., Courtois-Coutry N., Fay M., Cluzeaud F., Hummler E., Farman N. Coordinate control of Na, K-ATPase mRNA expression by aldosterone, vasopressin and cell sodium delivery in the cortical collecting duct. Cell Mol. Biol. (Noisy-le-grand) 2001, 47:247-253.
36. Nielsen J., Kwon T.H., Frøkiaer J., Knepper M.A., Nielsen S. Maintained ENaC trafficking in aldosterone-infused rats during mineralocorticoid and glucocorticoid receptor blockade. Am. J. Physiol. Renal Physiol. 2007, 292:F382-F394.
37. Alvarez de la Rosa D., Coric T., Todorovic N., Shao D., Wang T., Canessa C.M. Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney. J. Physiol. 2003, 551:455-466.
38. Funder J.W. Reconsidering the roles of mineralocorticoid receptor. Hypertension 2009, 53:286-290.
39. Siragy H.M., Carey R.M. Role of the intrarenal renin-angiotensin-aldosterone system in chronic kidney disease. Am. J. Nephrol. 2010, 31:541-550.
40. Xue C., Siragy H.M. Local renal aldosterone system and its regulation by salt, diabetes, and angiotensin II type 1 receptor. Hypertension 2005, 46:584-590.
41. Mejía-Vilet J.M., Ramírez V., Cruz C., Uribe N., Gamba G., Bobadilla N.A. Renal ischemia-reperfusion injury is prevented by the mineralocorticoid receptor blocker spironolactone. Am. J. Physiol. Renal. Physiol. 2007, 293:F78-F86.
42. Ramírez V., Trujillo J., Valdes R., Uribe N., Cruz C., Gamba G., Bobadilla N.A. Adrenalectomy prevents renal ischemia-reperfusion injury. Am. J. Physiol. Renal Physiol. 2009, 297:F932-F942.
43. Wang X.Y., Masilamani S., Nielsen J., Kwon T.H., Brooks H.L., Nielsen S., Knepper M.A. The renal thiazide-sensitive Na-Cl cotransporter as mediator of the aldosterone-escape phenomenon. J. Clin. Invest. 2001, 108:215-222.
44. Turban S., Wang X.Y., Knepper M.A. Regulation of NHE3, NKCC2, and NCC abundance in kidney during aldosterone escape phenomenon: role of NO. Am. J. Physiol. Renal Physiol. 2003, 285:F843-F851.
45. Brem A.S., Morris D.J., Ge Y., Dworkin L.D., Tolbert E., Gong R. Direct fibrogenic effects of aldosterone on normotensive kidney: an effect modified by 11{beta}-HSD activity. Am. J. Physiol. Renal Physiol. 2010, 298:F1178-F1187.
46. Fukuda S., Horimai C., Harada K., Wakamatsu T., Fukasawa H., Muto S., Itai A., Hayashi M. Aldosterone-induced kidney injury is mediated by NFκB activation. Clin. Exp. Nephrol. 2011, 15:41-49.