Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 10, 2013, Pages 4513-4523

  Delvaux, David ^a,d   Kerff, Frédéric ^a   Murty, Mamidanna R V S ^a,e   Lakaye, Bernard ^a   Czerniecki, Jan ^a,f   Kohn, Gregory ^a   Wins, Pierre ^a   Herman, Raphaël ^a   Gabelica, Valérie ^a,g,h   Heuze, Fabien ^b   Tordoir, Xavier ^b   Marée, Raphaël ^b,c   Matagne, André ^a   Charlier, Paulette ^a   De Pauw, Edwin ^a   Bettendorff, Lucien ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b GIGA Bioinformatics and Modeling   (Belgium)

^c GIGA Bioinformatics Core Facility   (Belgium)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^e INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^f INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

^g UNIVERSITÉ DE BORDEAUX   (France)

^h INSERM U869   (France)

Author keywords

CyaB, ThTPase; Divalent cation; Thiamine triphosphate; Triphosphate tunnel metalloenzyme; Tripolyphosphate

Indexed keywords

THIAMINE TRIPHOSPHATASE; THIAMINE TRIPHOSPHATE;

ARTICLE; CATALYSIS; CIRCULAR DICHROISM; CONTROLLED STUDY; CRYSTALLIZATION; CRYSTALLOGRAPHY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; HUMAN; MASS SPECTROMETRY; MOLECULAR DOCKING; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SEA ANEMONE; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; ZEBRA FISH;

CD; CIRCULAR DICHROISM; CYAB, THTPASE; DIVALENT CATION; INORGANIC TRIPOLYPHOSPHATE; PPP(I); PPPASE; THDP; THIAMINE DIPHOSPHATE; THIAMINE MONOPHOSPHATE; THIAMINE TRIPHOSPHATASE; THIAMINE TRIPHOSPHATE; THMP; THTP; THTPASE; TRIPHOSPHATE TUNNEL METALLOENZYME; TRIPOLYPHOSPHATASE; TRIPOLYPHOSPHATE; TTM;

AMINO ACID SEQUENCE; ANIMALS; BIOCATALYSIS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTRATE SPECIFICITY; THIAMIN-TRIPHOSPHATASE;

ACTINIARIA; AVES; CNIDARIA; DANIO RERIO; MAMMALIA; METAZOA;

EID: 84879478059     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.05.014     Document Type: Article

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