Structure-function analysis of Plasmodium RNA triphosphatase and description of a triphosphate tunnel metalloenzyme superfamily that includes Cet1-like RNA triphosphatases and CYTH proteins

RNA

Volumn 12, Issue 8, 2006, Pages 1468-1474

  Gong, Chunling ^a   Smith, Paul ^a   Shuman, Stewart ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Enzyme evolution; Malaria; Phosphohydrolase; RNA capping

Indexed keywords

ADENYLATE CYCLASE; BACTERIAL PROTEIN; METALLOPROTEIN; MICROBIAL ENZYME; PHOSPHATASE; PROTEIN CET1; PROTEIN CYTH; PROTEIN PBD 1YEM; PROTEIN PDB 2ACA; RNA; RNA TRIPHOSPHATASE; THIAMINE TRIPHOSPHATASE; TRIPHOSPHATE TUNNEL METALLOENZYME; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; MUTAGENESIS; PEPTIDE MAPPING; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RESIDUE ANALYSIS; STRUCTURE ACTIVITY RELATION;

ACID ANHYDRIDE HYDROLASES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CATALYTIC DOMAIN; CONSERVED SEQUENCE; MANGANESE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOSIDE-TRIPHOSPHATASE; PHOSPHATES; PLASMODIUM; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; RNA CAPS; RNA, PROTOZOAN; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; SULFATES;

ARCHAEA; BACTERIA (MICROORGANISMS); EUKARYOTA; FUNGI; MAMMALIA; PLASMODIUM (APICOMPLEXA); PLASMODIUM FALCIPARUM; PROTOZOA; PYROCOCCUS; VIBRIO;

EID: 33746571989     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.119806     Document Type: Article

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