Mitochondrial permeability transition in the diabetic heart: Contributions of thiol redox state and mitochondrial calcium to augmented reperfusion injury

Journal of Molecular and Cellular Cardiology

Volumn 52, Issue 5, 2012, Pages 1009-1018

  Sloan, Ruben C ^a   Moukdar, Fatiha ^a   Frasier, Chad R ^a   Patel, Hetal D ^a   Bostian, Phillip A ^a   Lust, Robert M ^a   Brown, David A ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Calcium; Diabetes; Heart; Ischemia; Mitochondria; Mitochondria targeted peptide; Permeability transition pore; Reactive oxygen species; Thiol

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; CALCIUM; CARDIOVASCULAR AGENT; CYCLOSPORIN A [4 N METHYLISOLEUCINE]; DIAMIDE; DITHIOTHREITOL; GLUTATHIONE; GLUTATHIONE DISULFIDE; MINOCYCLINE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MTP 131; REACTIVE OXYGEN METABOLITE; STREPTOZOCIN; THIOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DIABETIC PATIENT; DISEASE PREDISPOSITION; DRUG MECHANISM; DRUG TARGETING; EX VIVO STUDY; HEART INFARCTION SIZE; HEART MITOCHONDRION; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEMODYNAMICS; ISOLATED HEART; MALE; MITOCHONDRIAL PERMEABILITY; NONHUMAN; OXIDATION; OXIDATION REDUCTION STATE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; STREPTOZOCIN DIABETES;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; CARDIOTONIC AGENTS; CYCLOSPORINE; DIABETES MELLITUS, EXPERIMENTAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEART; HEMODYNAMICS; MALE; MINOCYCLINE; MITOCHONDRIA, HEART; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL REPERFUSION INJURY; OLIGOPEPTIDES; OXIDATION-REDUCTION; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; RATTUS;

EID: 84863418960     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.02.009     Document Type: Article

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