Lipid-based intravesical drug delivery systems with controlled release of trospium chloride for the urinary bladder

Journal of Controlled Release

Volumn 170, Issue 2, 2013, Pages 161-166

  Haupt, M ^a,b   Thommes, M ^a   Heidenreich, A ^b   Breitkreutz, J ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Intravesical drug delivery; Mini mould; Mini tablet; Overactive bladder; Solid lipid extrusion; Trospium chloride

Indexed keywords

CHLORINE COMPOUNDS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG PRODUCTS; EXTRUSION; MOLDS; X RAY DIFFRACTION;

ANTICHOLINERGIC DRUGS; DRUG DELIVERY SYSTEM; MINI-TABLET; OVERACTIVE BLADDER; POLYMORPHIC TRANSFORMATION; SOLID LIPID EXTRUSION; TROSPIUM CHLORIDE; WATER SOLUBLE DRUGS;

CONTROLLED DRUG DELIVERY;

TRISTEARIN; TROSPIUM CHLORIDE; BENZILIC ACID DERIVATIVE; DELAYED RELEASE FORMULATION; NORTROPANE DERIVATIVE; STEARIC ACID DERIVATIVE; TABLET; URINARY TRACT AGENT;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; LONG TERM CARE; MELTING POINT; OVERACTIVE BLADDER; PRIORITY JOURNAL; SUSTAINED RELEASE FORMULATION; TABLET; X RAY DIFFRACTION; BLADDER; CHEMISTRY; DELAYED RELEASE FORMULATION; POWDER DIFFRACTION; SOLUBILITY;

BENZILATES; CALORIMETRY, DIFFERENTIAL SCANNING; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; NORTROPANES; POWDER DIFFRACTION; SOLUBILITY; STEARATES; TABLETS; URINARY BLADDER; UROLOGICAL AGENTS; X-RAY DIFFRACTION;

EID: 84879471538     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.05.018     Document Type: Article

References (32)

1. G. Froehlich, S. Burmeister, A. Wiedemann, M. Bulitta, Intravesical instillation of trospium chloride, oxybutynin and verapamil for relaxation of the bladder detrusor muscle. A placebo controlled, randomized clinical test, Arzneimittelforschung 48 (1998) 486-491. (Pubitemid 28247635)
2. R. Scheife, M. Takeda, Central nervous system safety of anticholinergic drugs for the treatment of overactive bladder in the elderly, Clin. Ther. 27 (2005) 144-153. (Pubitemid 40462007)
3. A. Wiedemann, U. Schwantes, Antimuscarinic drugs for the treatment of overactive bladder: are they really all the same? - A comparative review of data pertaining to pharmacological and physiological aspects, Eur. J. Geriatr. 9 (2007) 29-42.
4. M. von Walter, I. Michaelis, G. Jakse, J.O. Grosse, Trospium chloride released from intravesically applied PLGA-based carriers decreases bladder contractility in an isolated whole pig bladder model, Eur. Urol. Suppl. 8 (2009) 178.
5. D. Singh-Franco, C. Machado, S. Tuteja, A. Zapantis, Trospium chloride for the treatment of overactive bladder with urge incontinence, Clin. Ther. 27 (2005) 511-530. (Pubitemid 40835963)
6. C.B. Packhaeuser, T. Kissel, On the design of in situ forming biodegradable parenteral depot systems based on insulin loaded dialkylaminoalkyl-amine-poly(vinyl alcohol)-g-poly(lactide-co-glycolide) nanoparticles, J. Control. Release 123 (2007) 131-140. (Pubitemid 47562140)
7. M. Gosau, B.W. Mueller, Release of gentamicin sulphate from biodegradable PLGA-implants produced by hot melt extrusion, Pharmazie 65 (2010) 487-492.
8. A. Brunner, K. Maeder, A. Goepferich, pH and osmotic pressure inside biodegradable microspheres during erosion, Pharm. Res. 16 (1999) 847-853. (Pubitemid 29284195)
9. J.M. Anderson, M.S. Shive, Biodegradation and biocompatibility of PLA and PLGA microspheres, Adv. Drug Deliv. Rev. 28 (1997) 5-24. (Pubitemid 27497671)
10. J.C. Middleton, A.J. Tipton, Synthetic biodegradable polymers as orthopedic devices, Biomaterials 21 (2000) 2335-2346.
11. S. Schulze, G. Winter, Lipid extrudates as novel sustained release systems for pharmaceutical proteins, J. Control. Release 134 (2009) 177-185.
12. M. Schwab, B. Kessler, E. Wolf, G. Jordan, S. Mohl, G. Winter, Correlation of in vivo and in vitro release data for rh-INF alpha lipid implants, Eur. J. Pharm. Biopharm. 70 (2008) 690-694.
13. C. Guse, S. Koennings, A. Maschke, M. Hacker, C. Becker, S. Schreiner, T. Blunk, T. Spruss, A. Goepferich, Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids, Int. J. Pharm. 314 (2006) 153-160.
14. G. D'Amico, C. Bazzi, Pathophysiology of proteinuria, Kidney Int. 63 (2003) 809-825. (Pubitemid 36315559)
15. B. Comte, C. Franceschi, M.O. Sadoulet, F. Silvy, D. Lafitte, L. Benkoel, A. Nganga, L. Daniel, J.P. Bernard, D. Lombardo, E. Mas, Detection of bile salt-dependent lipase, a 110 kDa pancreatic protein, in urines of healthy subjects, Kidney Int. 69 (2006) 1048-1055. (Pubitemid 43372180)
16. C. Chapus, M. Rovery, L. Sarda, R. Verger, Minireview on pancreatic lipase and colipase, Biochimie 70 (1988) 1223-1234. (Pubitemid 18259723)
17. W. Junge, K. Leybold, Detection of colipase in serum and urine of pancreatitis patients, Clin. Chim. Acta 123 (1982) 293-302. (Pubitemid 12098584)
18. Y. Alnouti, I.L. Csanaky, C.D. Klaassen, Quantitative-profiling of bile acids and their conjugates in mouse liver, bile, plasma, and urine using LC-MS/MS, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 873 (2008) 209-217.
19. I. Bobeldijk, M. Hekman, de Vries-van der Weij, L. Coulier, R. Ramaker, R. Kleemann, T. Kooistra, C. Rubingh, A. Freidig, E. Verheij, Quantitative profiling of bile acids in biofluids and tissues based on accurate mass high resolution LC-FF-MS: compound class targeting in a metabolomics workflow, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 871 (2008) 306-313.
20. F. Kreye, F. Siepmann, J. Siepmann, Drug release mechanisms of compressed lipid implants, Int. J. Pharm. 404 (2010) 27-35.
21. S. Mohl, G. Winter, Continuous release of rh-interferon alpha-2a from triglyceride matrices, J. Control. Release 97 (2004) 67-78. (Pubitemid 38624510)
22. F. Kreye, F. Siepmann, J. Siepmann, Lipid implants as drug delivery systems, Expert Opin. Drug Deliv. 5 (2008) 291-307. (Pubitemid 351454379)
23. J. Krause, M. Thommes, J. Breitkreutz, Immediate release pellets with lipid binders obtained by solvent-free cold extrusion, Eur. J. Pharm. Biopharm. 71 (2009) 138-144.
24. M. Windbergs, C.J. Strachan, P. Kleinebudde, Understanding the solid-state behaviour of triglyceride solid lipid extrudates and its influence on dissolution, Eur. J. Pharm. Biopharm. 71 (2009) 80-87.
25. F. Kreye, F. Siepmann, A. Zimmer, J.F. Willart, M. Descamps, J. Siepmann, Controlled release implants based on cast lipid blends, Eur. J. Pharm. Sci. 43 (2011) 78-83.
26. T. Pongjanyakul, N.J. Medlicott, I.G. Tucker, Melted glyceryl palmitostearate (GPS) pellets for protein delivery, Int. J. Pharm. 271 (2004) 53-62. (Pubitemid 38210084)
27. Y.E. Zhang, J.B. Schwartz, Melt granulation and heat treatment for wax matrix-controlled drug release, Drug Dev. Ind. Pharm. 29 (2003) 131-138. (Pubitemid 36292936)
28. F. Kreye, F. Siepmann, J.F. Willart, M. Descamps, J. Siepmann, Drug release mechanisms of cast lipid implants, Eur. J. Pharm. Biopharm. 78 (2011) 394-400.
29. K. Sato, Crystallization behaviour of fats and lipids - a review, Chem. Eng. Sci. 56 (2001) 2255-2265. (Pubitemid 33763447)
30. C. Guse, S. Koennings, F. Kreye, F. Siepmann, A. Goepferich, J. Siepmann, Drug release from lipid-based implants: elucidation of the underlying mass transport mechanisms, Int. J. Pharm. 314 (2006) 137-144.
31. N. Khan, D.Q.M. Craig, Role of blooming in determining the storage stability of lipid-based dosage forms, J. Pharm. Sci. 93 (2004) 2962-2971. (Pubitemid 39657800)
32. F. Kreye, F. Siepmann, A. Zimmer, J.F. Willart, M. Descamps, J. Siepmann, Cast lipid implants for controlled drug delivery: importance of the tempering conditions, J. Pharm. Sci. 100 (2011) 3471-3481.