Melted glyceryl palmitostearate (GPS) pellets for protein delivery

International Journal of Pharmaceutics

Volumn 271, Issue 1-2, 2004, Pages 53-62

  Pongjanyakul, Thaned ^b   Medlicott, Natalie J ^a   Tucker, Ian G ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b KHON KAEN UNIVERSITY   (Thailand)

Author keywords

Glyceryl palmitostearate; Lysozyme; Melted pellets; Percolation threshold; Polyethylene glycol

Indexed keywords

GELUCIRE; GLYCEROL PALMITOSTEARATE; LYSOZYME; MACROGOL 4000;

ARTICLE; COMPRESSION; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENZYME ACTIVITY; HYDROPHILICITY; IN VITRO STUDY; MELTING POINT; POROSITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

EID: 1142285523     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2003.10.017     Document Type: Article

References (27)

1. Allababidi S., Shah J.C. Efficacy and pharmacokinetics of site specific cefazolin delivery using biodegradable implants in the prevention of post-operative wound infections. Pharm. Res. 15:1998;325-333.
2. Bezemer J.M., Radersma R., Grijpma D.W., Dijkstra P.J., Feijen J., Blitterswijk C.A.V. Zero-order release of lysozyme from poly(ethylene glycol)/poly(bytylene terephthalate) matrices. J. Control. Release. 64:2000;179-192.
3. Bodmeier R., Paeratakul O., Chen H., Zhang W. Formulation of sustained release wax matrices within hard gelatin capsules in a fluidized bed. Drug Dev. Ind. Pharm. 16:1990;1505-1519.
4. Bonny J.D., Leuenberger H. Matrix type controlled release systems: II percolation effects in non-swellable matrices. Pharm. Acta Helv. 68:1993;25-33.
5. Caraballo I., Millan M., Rabasco A.M. Relationship between drug percolation threshold and particle size in matrix tablets. Pharm. Res. 13:1996;387-390.
6. Caraballo I., Melgoza L.M., Alvarez-Fuentes J., Soriano M.C., Rabasco A.M. Design of controlled release inert matrixes of naltrexone hydrochloride based on percolation concepts. Int. J. Pharm. 181:1999;23-30.
7. Cleek R.L., Ting K.C., Eskin S.G., Mikos A.G. Microparticles of poly(D,L-lactic co-glycolide)/poly(ethylene glycol) blends for controlled drug delivery. J. Control. Release. 48:1997;259-268.
8. Cleland, J.L., Langer, R., 1994. Formulation and delivery of proteins and peptides: design and development strategies. In: Cleland, J.L., Langer, R. (Eds.), Formulation and Delivery of Proteins and Peptides. American Chemical Society, Washington, pp. 1-19.
9. Craig, D.Q.M., 1995. The use of glycerides as controlled release matrices. In: Karsa, D.R., Stephenson, R.A. (Eds.), Excipients and Delivery Systems for Pharmaceutical Formulations. The Royal Society of Chemistry, Cambridge, pp. 148-173.
10. El-Arini S.K., Leuenberger H. Modeling of drug release from polymer matrices: effect of drug loading. Int. J. Pharm. 121:1995;141-148.
11. Gao Z., Crowley W.R., Shukla A.J., James J.R., Reger J.F. Controlled release of contraceptive steroids from biodegradable and injection gel formulations: in vivo evaluation. Pharm. Res. 12:1995;864-868.
12. Göpferich A. Bioerodible implants with programmable drug release. J. Control. Release. 44:1997;271-281.
13. Kaewvichit S., Tucker I.G. The release of macromolecules from fatty acid matrices: complete factorial study of factors affecting release. J. Pharm. Pharmacol. 46:1994;708-713.
14. Khan M.Z.I., Tucker I.G., Opdebeeck J.P. Cholesterol and lecithin implants for sustained release of antigen: release and erosion in vitro, and antibody response in mice. Int. J. Pharm. 76:1991;161-170.
15. Kim J.E., Kim S.R., Lee S.H., Lee C.H., Kim D.D. The effect of pore formers on the controlled release of cefadroxil from a polyurethane matrix. Int. J. Pharm. 201:2000;29-36.
16. Leuenberger H., Bonny J.D., Kolb M. Percolation effects in matrix-type controlled drug release systems. Int. J. Pharm. 115:1995;217-224.
17. Lin W.J., Yu C.C. Comparison of protein loaded poly(ε-caprolactone) microparticles prepared by the hot-melt technique. J. Microencapsulat. 18:2001;585-592.
18. Lloyd G.R., Craig D.Q.M., Smith A. An investigation into the production of paracetamol solid dispersions in PEG 4000 using hot stage differential interference contrast microscopy. Int. J. Pharm. 158:1997;39-46.
19. Malamataris S., Panagopoulou A., Hatzipantou P. Controlled release from glyceryl palmito-stearate matrices prepared by dry-heat granulation and compression at elevated temperature. Drug Dev. Ind. Pharm. 17:1991;1765-1777.
20. Martin, A., 1993. Physical Pharmacy, 4th edition. Lea & Febiger, Philadelphia.
21. Medlicott N.J., Tucker I.G. Pulsatile release from subcutaneous implants. Adv. Drug Del. Rev. 38:1999;139-149.
22. Nokhodchi A., Farid D., Najafi M., Adrangui M. Studies on controlled-release formulations of diclofenac sodium. Drug Dev. Ind. Pharm. 23:1997;1019-1023.
23. Reithmeier H., Herrmann J., Göpferich A. Lipid microparticles as a parenteral controlled release device for peptides. J. Control. Release. 73:2001;339-350.
24. Rhine W.D., Hsieh D.S.T., Langer R. Polymer for sustained macromolecule release: procedure to fabricate reproducible delivery systems and control release kinetics. J. Pharm. Sci. 69:1980;265-270.
25. Siegel R.A., Langer R. Control release of polypeptides and other macromolecules. Pharm. Res. 1:1984;2-10.
26. Sutananta W., Craig D.Q.M., Newton J.M. An evaluation of the mechanisms of drug release from glyceride bases. J. Pharm. Pharmacol. 47:1995;182-187.
27. Yamagata Y., Iga K., Ogawa Y. Novel sustained-release dosage forms of proteins using polyglycerol esters of fatty acids. J. Control. Release. 63:2000;319-329.