Melt granulation and heat treatment for wax matrix-controlled drug release

Drug Development and Industrial Pharmacy

Volumn 29, Issue 2, 2003, Pages 131-138

  Zhang, Yu E ^a,b   Schwartz, Joseph B ^a  

^a UNIVERSITY OF THE SCIENCES   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

Controlled release; Heat treatment; Matrix; Melt granulation; Wax

Indexed keywords

GLYCEROL BEHENATE; PHENYLPROPANOLAMINE; THEOPHYLLINE;

ARTICLE; CONTROLLED RELEASE FORMULATION; DENSITY; DRUG FORMULATION; DRUG SOLUBILITY; DRUG SYNTHESIS; HEAT TREATMENT; MATRIX TABLET; MELTING POINT; POROSITY; TABLET COMPRESSION; TEMPERATURE;

CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG STABILITY; EXCIPIENTS; FATTY ACIDS; HEATING; PHENYLPROPANOLAMINE; SOLUBILITY; TABLETS; THEOPHYLLINE; TIME FACTORS; WAXES;

EID: 0037219837     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-120016720     Document Type: Article

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