Bolus injection of newly synthesized vitamin e derivative ETS-GS for the treatment of acute severe ulcerative colitis in a mouse model: New vitamin e derivative for acute severe UC

International Journal of Colorectal Disease

Volumn 28, Issue 3, 2013, Pages 305-311

  Hiratsuka, Takahiro ^a   Inomata, Masafumi ^a   Hagiwara, Satoshi ^a   Kono, Yohei ^a   Shiraishi, Norio ^a   Noguchi, Takayuki ^a   Kitano, Seigo ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

ETS GS; Ulcerative colitis; Vitamin E derivative

Indexed keywords

ALPHA TOCOPHEROL DERIVATIVE; GAMMA GLUTAMYL [2 [[[3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2 (4,8,12 TRIMETHYLTRI DECYL) 2H 1 BENZOPYRAN 6 YL]OXY]CARBONYL] 3 OXO 3 [(2 SULFOETHYL)AMINO]PROPYL]CYSTEINYLGLYCINE SODIUM SALT; INTERLEUKIN 10; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BOLUS INJECTION; COLON LENGTH; COLON WEIGHT; CONTROLLED STUDY; DIGESTIVE TRACT PARAMETERS; DISEASE ACTIVITY INDEX; DISEASE SEVERITY; EXPERIMENTAL MOUSE; HISTOPATHOLOGY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCORING SYSTEM; ULCERATIVE COLITIS;

ANIMALS; CHEMOKINES; COLITIS, ULCERATIVE; COLON; DISEASE MODELS, ANIMAL; INFLAMMATION MEDIATORS; INJECTIONS; INTERLEUKIN-10; INTERLEUKIN-6; MALE; MICE; MICE, INBRED ICR; OLIGOPEPTIDES; ORGAN SIZE; VITAMIN E;

EID: 84879463464     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-012-1502-y     Document Type: Article

References (36)

1. Molodecky NA, Soon IS, Rabi DM et al (2012) Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 142:46-54
2. Katz JA (2000) Medical and surgical management of severe colitis. Semin Gastrointest Dis 11:18-32 (Pubitemid 30106152)
3. Van Assche G, Vermeire S, Rutgeerts P (2011) Management of acute severe ulcerative colitis. Gut 60:130-133
4. Ahmed L, Nazrul Islam S, Khan MN, Huque S, Ahsan M (2004) Antioxidant micronutrient profile (vitamin E, C, A, copper, zinc, iron) of colostrum: association with maternal characteristics. J Trop Pediatr 50:357-358 (Pubitemid 40017228)
5. Mirbagheri SA, Nezami BG, Assa S, Hajimahmoodi M (2008) Rectal administration of d-alpha tocopherol for active ulcerative colitis: a preliminary report. World J Gastroenterol 14:5990-5995
6. Stuyvesant VW, Jolley WB (1967) Anti-inflammatory activity of d-alpha-tocopherol (vitamin E) and linoleic acid. Nature 216:585-586
7. Cid L, Pararajasegaram G, Sevanian A et al (1992) Anti-inflammatory effects of vitamin E on experimental lens-induced uveitis. Int Ophthalmol 16:27-32
8. Rezk BM, van der Vijgh WJ, Bast A, Haenen GR (2007) Alpha-tocopheryl phosphate is a novel apoptotic agent. Front Biosci 12:2013-2019
9. Koonsvitsky BP, Berry DA, Jones MB et al (1997) Olestra affects serum concentrations of alpha-tocopherol and carotenoids but not vitamin D or vitamin K status in free-living subjects. J Nutr 127:1636S-1645S (Pubitemid 27329535)
10. Zhao Z, Satsu H, Fujisawa M et al (2008) Attenuation by dietary taurine of dextran sulfate sodium-induced colitis in mice and of THP-1-induced damage to intestinal Caco-2 cell monolayers. Amino Acids 35:217-224 (Pubitemid 351799190)
11. Giris M, Depboylu B, Dogru-Abbasoglu S et al (2008) Effect of taurine on oxidative stress and apoptosis-related protein expression in trinitrobenzene sulphonic acid-induced colitis. Clin Exp Immunol 152:102-110 (Pubitemid 351347551)
12. Oz HS, Chen TS, McClain CJ, de Villiers WJ (2005) Antioxidants as novel therapy in a murine model of colitis. J Nutr Biochem 16:297-304 (Pubitemid 41556919)
13. Carrier JC, Aghdassi E, Jeejeebhoy K, Allard JP (2006) Exacerbation of dextran sulfate sodium-induced colitis by dietary iron supplementation: role of NF-kappaB. Int J Colorectal Dis 21:381-387 (Pubitemid 43880544)
14. Hagiwara S, Koga H, Iwasaka H et al (2011) ETS-GS, a new antioxidant, ameliorates renal ischemia-reperfusion injury in a rodent model. J Surg Res 171:226-233
15. Hagiwara S, Koga H, Iwasaka H et al (2011) ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury. J Surg Res 171:734-741
16. Murai R, Kanbe T, Mukoyama T et al (2007) Effect of rectal administration of rebamipide on dextran sulfate sodium-induced colitis: role of hepatocyte growth factor. Inflamm Res 56:240-245 (Pubitemid 47026290)
17. Cooper HS, Murthy SN, Shah RS, Sedergran DJ (1993) Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69:238-249
18. Yao J, Wang JY, Liu L et al (2010) Anti-oxidant effects of resveratrol on mice with DSS-induced ulcerative colitis. Arch Med Res 41:288-294
19. Alex P, Zachos NC, Nguyen T et al (2009) Distinct cytokine patterns identified from multiplex profiles of murine DSS and TNBS-induced colitis. Inflamm Bowel Dis 15:341-352
20. Kostadinova FI, Baba T, Ishida Y et al (2010) Crucial involvement of the CX3CR1-CX3CL1 axis in dextran sulfate sodium-mediated acute colitis in mice. J Leukoc Biol 88:133-143
21. Holtkamp W, Stollberg T, Reis HE (1995) Serum interleukin-6 is related to disease activity but not disease specificity in inflammatory bowel disease. J Clin Gastroenterol 20:123-126
22. Joshi R, Kumar S, Unnikrishnan M, Mukherjee T (2005) Free radical scavenging reactions of sulfasalazine, 5-aminosalicylic acid and sulfapyridine: mechanistic aspects and antioxidant activity. Free Radic Res 39:1163-1172 (Pubitemid 41601418)
23. Suzuki Y, Matsumoto T, Okamoto S, Hibi T (2008) A lecithinized superoxide dismutase (PC-SOD) improves ulcerative colitis. Colorectal Dis 10:931-934
24. Broeyer FJ, van Aken BE, Suzuki J et al (2008) The pharmacokinetics and effects of a long-acting preparation of superoxide dismutase (PC-SOD) in man. Br J Clin Pharmacol 65:22-29 (Pubitemid 350265162)
25. Suzuki J, Broeyer F, Cohen A, Takebe M, Burggraaf J, Mizushima Y (2008) Pharmacokinetics of PC-SOD, a lecithinized recombinant superoxide dismutase, after single- and multiple-dose administration to healthy Japanese and Caucasian volunteers. J Clin Pharmacol 48:184-192
26. Rezaie A, Parker RD, Abdollahi M (2007) Oxidative stress and pathogenesis of inflammatory bowel disease: an epiphenomenon or the cause? Dig Dis Sci 52:2015-2021 (Pubitemid 47246507)
27. Tamaki H, Nakamura H, Nishio A et al (2006) Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production. Gastroenterology 131:1110-1121 (Pubitemid 44498706)
28. Seo JY, Kim H, Seo JT, Kim KH (2002) Oxidative stress induced cytokine production in isolated rat pancreatic acinar cells: effects of small-molecule antioxidants. Pharmacology 64:63-70 (Pubitemid 34114191)
29. Strober W, Fuss IJ (2011) Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. Gastroenterology 140:1756-1767
30. Sanchez-Munoz F, Dominguez-Lopez A, Yamamoto-Furusho JK (2008) Role of cytokines in inflammatory bowel disease. World J Gastroenterol 14:4280-4288
31. Song F, Ito K, Denning TL et al (1999) Expression of the neutrophil chemokine KC in the colon of mice with enterocolitis and by intestinal epithelial cell lines: effects of flora and proinflammatory cytokines. J Immunol 162:2275-2280 (Pubitemid 29288851)
32. Aleksandra Nielsen A, Nederby Nielsen J, Schmedes A, Brandslund I, Hey H (2005) Saliva interleukin-6 in patients with inflammatory bowel disease. Scand J Gastroenterol 40:1444-1448 (Pubitemid 43028206)
33. Egesten A, Eliasson M, Olin AI et al (2007) The proinflammatory CXC-chemokines GRO-alpha/CXCL1 and MIG/CXCL9 are concomitantly expressed in ulcerative colitis and decrease during treatment with topical corticosteroids. Int J Colorectal Dis 22:1421-1427 (Pubitemid 47543330)
34. Lindsay JO, Sandison A, Cohen P, Brennan FM, Hodgson HJ (2004) IL-10 gene therapy is therapeutic for dextran sodium sulfate-induced murine colitis. Dig Dis Sci 49:1327-1334 (Pubitemid 39178107)
35. Yao J, Wang JY, Lai MG et al (2011) Treatment of mice with dextran sulfate sodium-induced colitis with human interleukin 10 secreted by transformed Bifidobacterium longum. Mol Pharm 8:488-497
36. King MR, Ismail AS, Davis LS, Karp DR (2006) Oxidative stress promotes polarization of human T cell differentiation toward a T helper 2 phenotype. J Immunol 176:2765-2772