TERT's role in colorectal carcinogenesis

Molecular Carcinogenesis

Volumn 52, Issue 7, 2013, Pages 507-513

  Pellatt, Andrew J ^a   Wolff, Roger K ^a   Herrick, Jennifer ^a   Lundgreen, Abbie ^a   Slattery, Martha L ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

BMI; CIMP+; Colon cancer; Rectal cancer; TERT

Indexed keywords

ACETYLSALICYLIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; AGED; ALLELE; ARTICLE; BODY MASS; CANCER RISK; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING;

ADULT; AGED; CASE-CONTROL STUDIES; CELL TRANSFORMATION, NEOPLASTIC; COLONIC NEOPLASMS; FEMALE; GENOTYPE; HUMANS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; RECTAL NEOPLASMS; RISK FACTORS; TELOMERASE; TELOMERE; UTAH;

EID: 84879462177     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.21885     Document Type: Article

References (33)

1. Soreide K, Gudlaugsson E, Skaland I, et al. Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin. Int J Colorectal Dis 2008; 23: 389- 400.
2. Simsek BC, Pehlivan S, Karaoglu A. Human telomerase reverse transcriptase expression in colorectal tumors: Correlations with immunohistochemical expression and clinicopathologic features. Ann Diagn Pathol 2010; 14: 413- 417.
3. Svec J, Ergang P, Mandys V, Kment M, Pacha J. Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models. Int J Exp Pathol 2010; 91: 44- 53.
4. Zinn RL, Pruitt K, Eguchi S, Baylin SB, Herman JG. hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site. Cancer Res 2007; 67: 194- 201.
5. Mirabello L, Yu K, Kraft P, et al. The association of telomere length and genetic variation in telomere biology genes. Hum Mutat 2010; 31: 1050- 1058.
6. Peters U, Hutter CM, Hsu L, et al. Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet 2012; 131: 217- 234.
7. Jones AM, Beggs AD, Carvajal-Carmona L, et al. TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres. Gut 2012; 61: 248- 254.
8. Bautista CV, Felis CP, Espinet JM, Garcia JB, Salas JV. Telomerase activity is a prognostic factor for recurrence and survival in rectal cancer. Dis Colon Rectum 2007; 50: 611- 620.
9. Watson AJ, Collins PD. Colon cancer: A civilization disorder. Dig Dis 2011; 29: 222- 228.
10. Slattery ML, Potter J, Caan B, et al. Energy balance and colon cancer-Beyond physical activity. Cancer Res 1997; 57: 75- 80.
11. Slattery ML, Edwards S, Curtin K, et al. Physical activity and colorectal cancer. Am J Epidemiol 2003; 158: 214- 224.
12. Edwards S, Slattery ML, Mori M, et al. Am J Epidemiol 1994; 140: 1020- 1028.
13. Slattery ML, Jacobs DR, Jr. Assessment of ability to recall physical activity of several years ago. Ann Epidemiol 1995; 5: 292- 296.
14. Slattery ML, Herrick JS, Lundgreen A, Fitzpatrick FA, Curtin K, Wolff RK. Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1. Carcinogenesis 2010; 31: 1604- 1611.
15. Samowitz WS, Curtin K, Ma KN, et al. Prognostic significance of p53 mutations in colon cancer at the population level. Int J Cancer 2002; 99: 597- 602.
16. Slattery ML, Curtin K, Anderson K, et al. Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors. J Natl Cancer Inst 2000; 92: 1831- 1836.
17. Samowitz WS, Curtin K, Schaffer D, Robertson M, Leppert M, Slattery ML. Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: A population-based study. Cancer Epidemiol Biomarkers Prev 2000; 9: 1193- 1197.
18. Slattery ML, Curtin K, Sweeney C, et al. Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int J Cancer 2007; 120: 656- 663.
19. Slattery ML, Curtin K, Wolff RK, et al. A comparison of colon and rectal somatic DNA alterations. Dis Colon Rectum 2009; 52: 1304- 1311.
20. Conneely KN, Boehnke M. So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests. Am J Hum Genet 2007; 81: 1158- 1168.
21. Pooley KA, Tyrer J, Shah M, et al. No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk. Cancer Epidemiol Biomarkers Prev 2010; 19: 1862- 1865.
22. Slattery ML, Murtaugh M, Caan B, Ma KN, Wolff R, Samowitz W. Associations between BMI, energy intake, energy expenditure, VDR genotype and colon and rectal cancers (United States). Cancer Causes Control 2004; 15: 863- 872.
23. Sastry PS, Parikh P. The earlier age of onset of malignancy in developing world is related to overall infection burden and could be due to the effect on telomere length. Med Hypotheses 2003; 60: 573- 574.
24. Al-Attas OS, Al-Daghri N, Bamakhramah A, Shaun Sabico S, McTernan P, Huang TT. Telomere length in relation to insulin resistance, inflammation and obesity among Arab youth. Acta Paediatr 2010; 99: 896- 899.
25. Al-Attas OS, Al-Daghri NM, Alokail MS, et al. Adiposity and insulin resistance correlate with telomere length in middle-aged Arabs: The influence of circulating adiponectin. Eur J Endocrinol 2010; 163: 601- 607.
26. Njajou OT, Cawthon RM, Blackburn EH, et al. Shorter telomeres are associated with obesity and weight gain in the elderly. Int J Obes (Lond) 2011; [Epub ahead of print].
27. Saliques S, Teyssier JR, Vergely C, et al. Circulating leukocyte telomere length and oxidative stress: A new target for statin therapy. Atherosclerosis 2011; 219: 753- 760.
28. Amsellem V, Gary-Bobo G, Marcos E, et al. Telomere dysfunction causes sustained inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2011; 184: 1358- 1366.
29. Calvert PA, Liew TV, Gorenne I, et al. Leukocyte telomere length is associated with high-risk plaques on virtual histology intravascular ultrasound and increased proinflammatory activity. Arterioscler Thromb Vasc Biol 2011; 31: 2157- 2164.
30. O'Donovan A, Pantell MS, Puterman E, et al. Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study. PloS ONE 2011; 6: e19687.
31. Rampazzo E, Bertorelle R, Serra L, et al. Relationship between telomere shortening, genetic instability, and site of tumour origin in colorectal cancers. Br J Cancer 2010; 102: 1300- 1305.
32. Takagi S, Kinouchi Y, Hiwatashi N, et al. Relationship between microsatellite instability and telomere shortening in colorectal cancer. Dis Colon Rectum 2000; 43: S12- S17.
33. Takagi S, Kinouchi Y, Hiwatashi N, et al. Telomere shortening and the clinicopathologic characteristics of human colorectal carcinomas. Cancer 1999; 86: 1431- 1436.