Human telomerase reverse transcriptase expression in colorectal tumors: Correlations with immunohistochemical expressionand clinicopathologic features

Annals of Diagnostic Pathology

Volumn 14, Issue 6, 2010, Pages 413-417

  Simsek, Bengu Cobanoglu ^a   Pehlivan, Sultan ^a   Karaoglu, Aziz ^b  

^a FIRAT UNIVERSITY   (Turkey)

^b DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

Clinicopathologic features; Colorectal tumors; HTERT; Immunohistochemistry

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE;

ADENOMATOUS POLYP; ADULT; AGED; ARTICLE; CLINICAL FEATURE; COLON ADENOCARCINOMA; COLON POLYP; COLORECTAL CANCER; CORRELATION ANALYSIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECTUM CARCINOMA; RECTUM POLYP; TUMOR VOLUME;

ADENOCARCINOMA; ADENOMA; ADENOMATOUS POLYPS; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; TELOMERASE; TUMOR MARKERS, BIOLOGICAL;

EID: 78349276530     PISSN: 10929134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anndiagpath.2010.06.007     Document Type: Article

References (22)

1. Brümmendorf T.H. Telomerase activity-a prognostic factor in colorectal cancer? Onkologie 2005 550 551
2. Hao Z.M., Luo J.Y., Cheng J., Li L., He D., and Wang Q.Y. Intensive inhibition of hTERT expression by a ribozyme induces rapid apoptosis of cancer cells through a telomere length-independent pathway Cancer Biol Ther 2005 1098 1103
3. Yan P., Benhattar J., Seelentag W., Stehle J.C., and Bosman F.T. Immunohistochemical localization of hTERT protein in human tissues Histochem Cell Biol 2004 391 397
4. Niiyama H., Mizumoto K., Sato N., Nagai E., Mibu R., and Fukui T. Quantitative analysis of hTERT mRNA expression in colorectal cancer Am J Gastroenterol 2001 1895 1900
5. Bautista C.V., Felis C.P., Espinet J.M., García J.B., and Salas J.V. Telomerase activity is a prognostic factor for recurrence and survival in rectal cancer Dis Colon Rectum 2007 611 620
6. Tahara H., Yasui W., Tahara E., Fujimoto J., Ito K., and Tamai K. Immunohistochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue section Oncogene 1999 1561 1567
7. Volpi A., Bravaccini S., Medri L., Cerasoli S., Gaudio M., and Amadori D. Usefulness of immunohistochemical detection of human telomerase reverse transcriptase Cell Oncol 2005 347 353
8. Hiyama E., and Hiyama K. Telomerase as tumor marker Cancer Lett 2003 221 233
9. Kammori M., Takubo K., Nakamura K., Furugouri E., Endo H., and Kanauchi H. Telomerase activity and telomere length in benign and malignant human thyroid tissues Cancer Lett 2000 175 181
10. Kobayashi T., Kubota K., Takayama T., and Makuuchi M. Telomerase activity as a predictive marker for recurrence of hepatocellular carcinoma after hepatectomy Am J Surg 2001 284 288
11. Marchetti A., Bertacca G., Buttitta F., Chella A., Quattrocolo G., and Angeletti C.A. Telomerase activity as a prognostic indicator in stage I non-small cell lung cancer Clin Cancer Res 1999 2077 2081
12. Desmaze C., Soria J.C., Freulet-Marrière M.A., Mathieu N., and Sabatier L. Telomere-driven genomic instability in cancer cells Cancer Lett 2003 73 82
13. Reddel R.R., and Bryan T.M. Alternative lengthening of telomeres: dangerous road less travelled Lancet 2003 1840 1841
14. Lida A., Yamaguchi A., and Hirose K. Telomerase activity in colorectal cancer and its relationship to bcl-2 expression J Surg Oncol 2000 219 223
15. Engelhardt M., Drullinsky P., Guillem J., and Moore M.A. Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer Clin Cancer Res 1997 931 941
16. Garcia-Aranda C., de Juan C., Diaz-Lopez A., Sanchez-Pernaute A., Torres A.J., Diaz-Rubio E., and Balibrea J.L. Correlations of telomere length, telomerase activity, and telomeric-repeat binding factor 1 expression in colorectal carcinoma Cancer 2006 541 551
17. Shoji Y., Yoshinaga K., Inoue A., Iwasaki A., and Sugihara K. Quantification of telomerase activity in sporadic colorectal carcinoma: association with tumor growth and venous invasion Cancer 2000 1304 1309
18. Brown T., Aldous W., Lance R., Blaser J., Baker T., and Williard W. The association between telomerase, p53, and clinical staging in colorectal cancer Am J Surg 1998 364 366
19. Tang R., Cheng A.J., Wang J.Y., and Wang T.C. Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis Cancer Res 1998 4052 4054.
20. Lukman K., Maskoen A.M., Achmad T.H., Hanafi B., and Karnadihardja W. Telomerase activity in different clinical staging of colorectal adenocarcinoma Gan To Kagaku Ryoho 2000 491 497
21. Abe N., Watanabe T., Nakashima M., Masaki T., Mori T., and Sugiyama M. Quantitative analysis of telomerase activity: a potential diagnostic tool for colorectal carcinoma Hepatogastroenterology 2001 692 695
22. Ghori A., Usselmann B., Ferryman S., Morris A., and Fraser I. Telomerase expression of malignant epithelial cells correlates with Dukes' stage in colorectal cancer Colorectal Dis 2002 441 446