Discovery of novel andrographolide derivatives as cytotoxic agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 14, 2013, Pages 4056-4060

  Wei, Shanfu ^a,b   Tang, Yan Bo ^a   Hua, Huiming ^b   Ohkoshi, Emika ^c   Goto, Masuo ^c   Wang, Li Ting ^c   Lee, Kuo Hsiung ^c,d   Xiao, Zhiyan ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c UNC Hamner Institute for Drug Safety Sciences   (United States)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Andrographolide derivatives; Cytotoxicity; Labdane diterpenes; Microtubule dynamics

Indexed keywords

ANDROGRAPHOLIDE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT;

ARTICLE; CANCER INHIBITION; CATALYSIS; DRUG CYTOTOXICITY; ESTERIFICATION; ETHERIFICATION; IMMUNOCYTOCHEMISTRY; METAPHASE; MICROTUBULE; PHENOTYPE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

ANTINEOPLASTIC AGENTS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; DITERPENES; DRUG EVALUATION, PRECLINICAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICROTUBULES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84879419927     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.05.061     Document Type: Article

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