CaMKIIβ-mediated LIM-kinase activation plays a crucial role in BDNF-induced neuritogenesis

Genes to Cells

Volumn 18, Issue 7, 2013, Pages 533-543

  Saito, Akihiko ^a   Miyajima, Ken ^a   Akatsuka, Junichi ^a   Kondo, Hiroshi ^a   Mashiko, Toshiya ^a   Kiuchi, Tai ^a   Ohashi, Kazumasa ^a   Mizuno, Kensaku ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE I; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; COFILIN; LIM KINASE; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE;

ARTICLE; ENZYME ACTIVATION; GENE INACTIVATION; IN VITRO STUDY; NERVE FIBER GROWTH; NEURITE; NEURITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; BENZYLAMINES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CARRIER PROTEINS; CELLS, CULTURED; LIM KINASES; NEURITES; NEUROGENESIS; NEURONS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

RATTUS;

EID: 84879419730     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/gtc.12054     Document Type: Article

References (47)

1. Aizawa, H., Wakatsuki, S., Ishii, A., Moriyama, K., Sasaki, Y., Ohashi, K., Sekine-Aizawa, Y., Sehara-Fujisawa, A., Mizuno, K., Goshima, Y. & Yahara, I. (2001) Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse. Nat. Neurosci. 4, 367-373.
2. Bamburg, J.R. (1999) Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu. Rev. Cell Dev. Biol. 15, 185-230.
3. Banker, G. & Goslin, K. (1998) Culturing Nerve Cells, 2nd edn. Cambridge, MA: MIT Press.
4. Cheung, Z.H., Chin, W.H., Chen, Y., Ng, Y.P. & Ip, N.Y. (2007) Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons. PLoS Biol. 5, 865-877.
5. Dent, E.W., Kwiatkowski, A.V., Mebane, L.M., Philippar, U., Barzik, M., Rubinson, D.A., Gupton, S., Van Veen, J.E., Furman, C., Zhang, J., Alberts, A.S., Mori, S. & Gertler, F.B. (2007) Filopodia are required for cortical neurite initiation. Nat. Cell Biol. 9, 1347-1359.
6. Dijkhuizen, P.A. & Ghosh, A. (2005) BDNF regulates primary dendrite formation in cortical neurons via the PI3-kinase and MAP kinase signaling pathways. J. Neurobiol. 62, 278-288.
7. Edwards, D.C., Sanders, L.C., Bokoch, G.M. & Gill, G.N. (1999) Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPases signaling to actin cytoskeletal dynamics. Nat. Cell Biol. 1, 253-259.
8. Endo, M., Ohashi, K. & Mizuno, K. (2007) LIM kinase and slingshot are critical for neurite extension. J. Biol. Chem. 282, 13692-13702.
9. Endo, M., Ohashi, K., Sasaki, Y., Goshima, Y., Niwa, R., Uemura, T. & Mizuno, K. (2003) Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin. J. Neurosci. 23, 2527-2537.
10. Fink, C.C., Bayer, K.U., Myers, J.W., Ferrell, J.E. Jr., Schulman, H. & Meyer, T. (2003) Selective regulation of neurite extension and synapse formation by the β but not the α isoform of CaMKII. Neuron 39, 283-297.
11. Gorski, J.A., Zeiler, S.R., Tamowski, S. & Jones, K.R. (2003) Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites. J. Neurosci. 23, 6856-6865.
12. Horch, H.W., Kruttgen, A., Portbury, S.D. & Katz, L.C. (1999) Destabilization of cortical dendrites and spines by BDNF. Neuron 23, 353-364.
13. Horita, Y., Ohashi, K., Mukai, M., Inoue, M. & Mizuno, K. (2008) Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase. J. Biol. Chem. 283, 6013-6021.
14. Jan, Y.N. & Jan, L.Y. (2010) Branching out: mechanisms of dendritic arborization. Nat. Rev. Neurosci. 11, 316-328.
15. Konur, S. & Ghosh, A. (2005) Calcium signaling and the control of dendritic development. Neuron 46, 401-405.
16. Kulkarni, V.A. & Firestein, B.L. (2012) The dendritic tree and brain disorders. Mol. Cell. Neurosci. 50, 10-20.
17. Lee-Hoeflich, S.T., Causing, C.G., Podkowa, M., Zhao, X., Wrana, J.L. & Attisano, L. (2004) Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis. EMBO J. 23, 4792-4801.
18. Lin, Y.C. & Redmond, L. (2008) CaMKIIβ binding to stable F-actin in vivo regulates F-actin filament stability. Proc. Natl Acad. Sci. USA 105, 15791-15796.
19. Luo, L. (2000) Rho GTPases in neuronal morphogenesis. Nat. Rev. Neurosci. 1, 173-180.
20. McAllister, A.K. (2000) Cellular and molecular mechanisms of dendrite growth. Cereb. Cortex 10, 963-973.
21. McAllister, A.K., Katz, L.C. & Lo, D.C. (1997) Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron 18, 767-778.
22. McAllister, A.K., Lo, D.C. & Katz, L.C. (1995) Neurotrophins regulate dendritic growth in developing visual cortex. Neuron 15, 791-803.
23. Meng, Y., Zhang, Y., Tregoubov, V., Janus, C., Cruz, L., Jackson, M., Lu, W.Y., MacDonald, J.F., Wang, J.Y., Falls, D.L. & Jia, Z. (2002) Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice. Neuron 35, 121-133.
24. Miller, F.D. & Kaplan, D.R. (2003) Signaling mechanisms underlying dendrite formation. Curr. Opin. Neurobiol. 13, 391-398.
25. Mizuno, K. (2013) Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation. Cell. Signal. 25, 457-469.
26. Mori, T., Okano, I., Mizuno, K., Tohyama, M. & Wanaka, A. (1997) Comparison of tissue distribution of two novel serine/threonine kinase genes containing the LIM motif (LIMK-1 and LIMK-2) in the developing rat. Brain Res. Mol. Brain Res. 45, 247-254.
27. Nishita, M., Tomizawa, C., Yamamoto, M., Horita, Y., Ohashi, K. & Mizuno, K. (2005) Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J. Cell Biol. 171, 349-359.
28. Niwa, R., Nagata-Ohashi, K., Takeichi, M., Mizuno, K. & Uemura, T. (2002) Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell 108, 233-246.
29. Ohashi, K., Nagata, K., Maekawa, M., Ishizaki, T., Narumiya, S. & Mizuno, K. (2000) Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J. Biol. Chem. 275, 3577-3582.
30. Okamoto, K., Narayanan, R., Lee, S.H., Murata, K. & Hayashi, Y. (2007) The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure. Proc. Natl Acad. Sci. USA 104, 6418-6423.
31. Okano, I., Hiraoka, J., Otera, H., Nunoue, K., Ohashi, K., Iwashita, S., Hirai, M. & Mizuno, K. (1995) Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs. J. Biol. Chem. 270, 31321-31330.
32. Penzes, P., Cahill, M.E., Jones, K.A. & Srivastava, D.P. (2008) Convergent CaMK and RacGEF signals control dendritic structure and function. Trends Cell Biol. 18, 405-413.
33. Puram, S.V., Kim, A.H., Ikeuchi, Y., Wilson-Grady, J.T., Merdes, A., Gygi, S.P. & Bonni, A. (2011) A CaMKIIβ signaling pathway at the centrosome regulates dendrite patterning in the brain. Nat. Neurosci. 14, 973-983.
34. Redmond, L., Kashani, A.H. & Ghosh, A. (2002) Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription. Neuron 34, 999-1010.
35. Sarmiere, P.D. & Bamburg, J.R. (2004) Regulation of the neuronal actin cytoskeleton by ADF/cofilin. J. Neurobiol. 58, 103-117.
36. Schratt, G.M., Tuebing, F., Nigh, E.A., Kane, C.G., Sabatini, M.E., Kiebler, M. & Greenberg, M.E. (2006) A brain-specific microRNA regulates dendritic spine development. Nature 439, 283-289.
37. Scott, E.K. & Luo, L. (2001) How do dendrites take their shape? Nat. Neurosci. 4, 359-365.
38. Singh, B., Henneberger, C., Betances, D., Arevalo, M.A., Rodriguez-Tebar, A., Meier, J.C. & Grantyn, R. (2006) Altered balance of glutamatergic/GABAergic synaptic input and associated changes in dendrite morphology after BDNF expression in BDNF-deficient hippocampal neurons. J. Neurosci. 26, 7189-7200.
39. 2+/calmodulin-dependent protein kinases. Cell. Mol. Life Sci. 65, 2637-2657.
40. 2+/calmodulin-dependent protein kinase CLICK-III/CaMKIγ. Neuron 54, 755-770.
41. 2+/calmodulin-dependent protein kinase IV-mediated LIM kinase activation is critical for calcium signal-induced neurite outgrowth. J. Biol. Chem. 284, 28554-28562.
42. Wang, Y., Shibasaki, F. & Mizuno, K. (2005) Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin. J. Biol. Chem. 280, 12683-12689.
43. Wayman, G.A., Lee, Y.S., Tokumitsu, H., Silva, A.J. & Soderling, T.R. (2008) Calmodulin-kinases: modulators of neuronal development and plasticity. Neuron 59, 914-931.
44. Wen, Z., Han, L., Bamburg, J.R., Shim, S., Ming, G.L. & Zheng, J.Q. (2007) BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin. J. Cell Biol. 178, 107-119.
45. Whitford, K.L., Dijkhuizen, P., Polleux, F. & Ghosh, A. (2002) Molecular control of cortical dendrite development. Annu. Rev. Neurosci. 25, 127-149.
46. Wu, G.Y. & Cline, H.T. (1998) Stabilization of dendritic arbor structure in vivo by CaMKII. Science 279, 222-226.
47. Yang, N., Higuchi, O., Ohashi, K., Nagata, K., Wada, A., Kangawa, K., Nishida, E. & Mizuno, K. (1998) Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393, 809-812.