Bile acids induce CCN2 production through p38 MAP kinase activation in human bronchial epithelial cells: A factor contributing to airway fibrosis

Respirology

Volumn 13, Issue 7, 2008, Pages 983-989

  Perng, Diahn Warng ^a,b   Wu, Yu Chung ^a,b   Tsai, Cheng Chien ^a   Su, Kang Cheng ^a   Liu, Lung Yu ^a   Hsu, Wen Hu ^a,b   Lee, Yu Chin ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Airway epithelium; Bile acid; Connective tissue growth factor; Fibrosis; Transforming growth factor 1

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATING TRANSCRIPTION FACTOR 2; BILE ACID; CONNECTIVE TISSUE GROWTH FACTOR; DEXAMETHASONE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN CCN2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BRONCHUS MUCOSA; CELL CULTURE; CELL GROWTH; CELL STIMULATION; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LUNG FIBROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RISK FACTOR; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 2; BILE ACIDS AND SALTS; BLOTTING, WESTERN; BRONCHI; CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; DEXAMETHASONE; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROSIS; GENE EXPRESSION; GLUCOCORTICOIDS; HUMANS; IMIDAZOLES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PYRIDINES; RESPIRATORY MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1;

EID: 54349110094     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2008.01402.x     Document Type: Article

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