NGF Upregulates the Plasminogen Activation Inhibitor-1 in Neurons via the Calcineurin/NFAT Pathway and the Down Syndrome-Related Proteins DYRK1A and RCAN1 Attenuate This Effect

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Stefos, Georgios C ^a,b   Soppa, Ulf ^a   Dierssen, Mara ^b   Becker, Walter ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b CENTRE FOR GENOMIC REGULATION CRG   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; DUAL SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 1A; MESSENGER RNA; NERVE GROWTH FACTOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE; REGULATOR OF CALCINEURIN 1; REGULATOR PROTEIN; TACROLIMUS; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; BRAIN FUNCTION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DOWN SYNDROME; HIPPOCAMPUS; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; CALCINEURIN; CELL DIFFERENTIATION; DOWN SYNDROME; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; NERVE GROWTH FACTOR; NEURONS; NFATC TRANSCRIPTION FACTORS; PC12 CELLS; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RATS; SIGNAL TRANSDUCTION; UP-REGULATION;

RATTUS;

EID: 84879374129     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067470     Document Type: Article

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