메뉴 건너뛰기




Volumn 12, Issue 12, 2013, Pages 1922-1927

α-Fucosidase as a novel convenient biomarker for cellular senescence

Author keywords

Biomarker; Cellular senescence; Lysosome; fucosidase; galactosidase; glucuronidase

Indexed keywords

ALPHA LEVO FUCOSIDASE; BETA GALACTOSIDASE;

EID: 84879361184     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.24944     Document Type: Article
Times cited : (52)

References (41)
  • 1
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • PMID:13905658
    • Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961; 25:585-621; PMID:13905658; http://dx.doi.org/10. 1016/0014-4827(61)90192-6
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 2
    • 34548211521 scopus 로고    scopus 로고
    • The DNA damage signaling pathway connects oncogenic stress to cellular senescence
    • Mallette FA, Ferbeyre G. The DNA damage signaling pathway connects oncogenic stress to cellular senescence. Cell Cycle 2007; 6:1831-6; PMID:17671427; http://dx.doi.org/10.4161/cc.6.15.4516 (Pubitemid 47327900)
    • (2007) Cell Cycle , vol.6 , Issue.15 , pp. 1831-1836
    • Mallette, F.A.1    Ferbeyre, G.2
  • 4
    • 70349773104 scopus 로고    scopus 로고
    • Healing and hurting: Molecular mechanisms, functions, and pathologies of cellular senescence
    • PMID:19818705
    • Adams PD. Healing and hurting: Molecular mechanisms, functions, and pathologies of cellular senescence. Mol Cell 2009; 36:2-14; PMID:19818705; http://dx.doi.org/10.1016/j.molcel.2009.09.021
    • (2009) Mol Cell , vol.36 , pp. 2-14
    • Adams, P.D.1
  • 5
    • 78649804198 scopus 로고    scopus 로고
    • The centrosome and mitotic spindle apparatus in cancer and senescence
    • PMID:21088502
    • Schmidt S, Essmann F, Cirstea IC, Kuck F, Thakur HC, Singh M, et al. The centrosome and mitotic spindle apparatus in cancer and senescence. Cell Cycle 2010; 9:4469-73; PMID:21088502; http://dx.doi.org/10.4161/cc.9.22.13684
    • (2010) Cell Cycle , vol.9 , pp. 4469-4473
    • Schmidt, S.1    Essmann, F.2    Cirstea, I.C.3    Kuck, F.4    Thakur, H.C.5    Singh, M.6
  • 6
    • 84859265162 scopus 로고    scopus 로고
    • Senescence: A new weapon for cancer therapy
    • PMID:22245068
    • Acosta JC, Gil J. Senescence: A new weapon for cancer therapy. Trends Cell Biol 2012; 22:211-9; PMID:22245068; http://dx.doi.org/10.1016/j.tcb.2011. 11.006
    • (2012) Trends Cell Biol , vol.22 , pp. 211-219
    • Acosta, J.C.1    Gil, J.2
  • 7
    • 84873638532 scopus 로고    scopus 로고
    • Aging, cellular senescence, and cancer
    • PMID:23140366
    • Campisi J. Aging, cellular senescence, and cancer. Annu Rev Physiol 2013; 75:685-705; PMID:23140366; http://dx.doi.org/10.1146/annurev-physiol-030212- 183653
    • (2013) Annu Rev Physiol , vol.75 , pp. 685-705
    • Campisi, J.1
  • 8
    • 84874192617 scopus 로고    scopus 로고
    • T-helper-1-cell cytokines drive cancer into senescence
    • PMID:23376950
    • Braumüller H, Wieder T, Brenner E, Aßmann S, Hahn M, Alkhaled M, et al. T-helper-1-cell cytokines drive cancer into senescence. Nature 2013; 494:361-5; PMID:23376950; http://dx.doi.org/10.1038/nature11824
    • (2013) Nature , vol.494 , pp. 361-365
    • Braumüller, H.1    Wieder, T.2    Brenner, E.3    Aßmann, S.4    Hahn, M.5    Alkhaled, M.6
  • 9
    • 79961117100 scopus 로고    scopus 로고
    • The meaning of p16(ink4a) expression in tumors: Functional significance, clinical associations and future developments
    • PMID:21775818
    • Witkiewicz AK, Knudsen KE, Dicker AP, Knudsen ES. The meaning of p16(ink4a) expression in tumors: Functional significance, clinical associations and future developments. Cell Cycle 2011; 10:2497-503; PMID:21775818; http://dx.doi.org/10.4161/cc.10.15.16776
    • (2011) Cell Cycle , vol.10 , pp. 2497-2503
    • Witkiewicz, A.K.1    Knudsen, K.E.2    Dicker, A.P.3    Knudsen, E.S.4
  • 10
    • 33847780136 scopus 로고    scopus 로고
    • The multiple battles fought by anti-apoptotic p21
    • Jänicke RU, Sohn D, Essmann F, Schulze-Osthoff K. The multiple battles fought by anti-apoptotic p21. Cell Cycle 2007; 6:407-13; PMID:17312393; http://dx.doi.org/10.4161/cc.6.4.3855 (Pubitemid 46393442)
    • (2007) Cell Cycle , vol.6 , Issue.4 , pp. 407-413
    • Janicke, R.U.1    Sohn, D.2    Essmann, F.3    Schulze-Osthoff, K.4
  • 11
    • 84860319965 scopus 로고    scopus 로고
    • Oncogene-induced senescence results in marked metabolic and bioenergetic alterations
    • PMID:22421146
    • Quijano C, Cao L, Fergusson MM, Romero H, Liu J, Gutkind S, et al. Oncogene-induced senescence results in marked metabolic and bioenergetic alterations. Cell Cycle 2012; 11:1383-92; PMID:22421146; http://dx.doi.org/10. 4161/cc.19800
    • (2012) Cell Cycle , vol.11 , pp. 1383-1392
    • Quijano, C.1    Cao, L.2    Fergusson, M.M.3    Romero, H.4    Liu, J.5    Gutkind, S.6
  • 12
    • 33745712849 scopus 로고    scopus 로고
    • The power and the promise of oncogene-induced senescence markers
    • PMID:16723993
    • Collado M, Serrano M. The power and the promise of oncogene-induced senescence markers. Nat Rev Cancer 2006; 6:472-6; PMID:16723993; http://dx.doi.org/10.1038/nrc1884
    • (2006) Nat Rev Cancer , vol.6 , pp. 472-476
    • Collado, M.1    Serrano, M.2
  • 13
    • 0037667702 scopus 로고    scopus 로고
    • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
    • DOI 10.1016/S0092-8674(03)00401-X
    • Narita M, Nunez S, Heard E, Narita M, Lin AW, Hearn SA, et al. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 2003; 113:703-16; PMID:12809602; http://dx.doi.org/10. 1016/S0092-8674(03)00401-X (Pubitemid 36724935)
    • (2003) Cell , vol.113 , Issue.6 , pp. 703-716
    • Narita, M.1    Nunez, S.2    Heard, E.3    Narita, M.4    Lin, A.W.5    Hearn, S.A.6    Spector, D.L.7    Hannon, G.J.8    Lowe, S.W.9
  • 14
    • 84866741381 scopus 로고    scopus 로고
    • Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer
    • PMID:22952011
    • Sulli G, Di Micco R, d'Adda di Fagagna F. Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer. Nat Rev Cancer 2012; 12:709-20; PMID:22952011; http://dx.doi.org/10.1038/nrc3344
    • (2012) Nat Rev Cancer , vol.12 , pp. 709-720
    • Sulli, G.1    Di Micco, R.2    D'Adda Di Fagagna, F.3
  • 15
    • 78651104478 scopus 로고    scopus 로고
    • DNA-SCARS: Distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
    • PMID:21118958
    • Rodier F, Muñoz DP, Teachenor R, Chu V, Le O, Bhaumik D, et al. DNA-SCARS: Distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion. J Cell Sci 2011; 124:68-81; PMID:21118958; http://dx.doi.org/10.1242/jcs.071340
    • (2011) J Cell Sci , vol.124 , pp. 68-81
    • Rodier, F.1    Muñoz, D.P.2    Teachenor, R.3    Chu, V.4    Le O Bhaumik, D.5
  • 16
    • 77956988624 scopus 로고    scopus 로고
    • Quantitative assessment of markers for cell senescence
    • PMID:20117203
    • Lawless C, Wang C, Jurk D, Merz A, Zglinicki Tv, Passos JF. Quantitative assessment of markers for cell senescence. Exp Gerontol 2010; 45:772-8; PMID:20117203; http://dx.doi.org/10.1016/j.exger.2010.01.018
    • (2010) Exp Gerontol , vol.45 , pp. 772-778
    • Lawless, C.1    Wang, C.2    Jurk, D.3    Merz, A.4    Zglinicki, Tv.5    Passos, J.F.6
  • 17
    • 79851493300 scopus 로고    scopus 로고
    • Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type-and insult-dependent manner and follow expression of p16(ink4a)
    • PMID:21248468
    • Kosar M, Bartkova J, Hubackova S, Hodny Z, Lukas J, Bartek J. Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type-and insult-dependent manner and follow expression of p16(ink4a). Cell Cycle 2011; 10:457-68; PMID:21248468; http://dx.doi.org/10.4161/cc.10.3.14707
    • (2011) Cell Cycle , vol.10 , pp. 457-468
    • Kosar, M.1    Bartkova, J.2    Hubackova, S.3    Hodny, Z.4    Lukas, J.5    Bartek, J.6
  • 18
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • PMID:7568133
    • Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 1995; 92:9363-7; PMID:7568133; http://dx.doi.org/ 10.1073/pnas.92.20.9363
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3    Acosta, M.4    Scott, G.5    Roskelley, C.6
  • 19
    • 33646946746 scopus 로고    scopus 로고
    • Senescence-associated ß-galactosidase is lysosomal ß-galactosidase
    • PMID:16626397
    • Lee BY, Han JA, Im JS, Morrone A, Johung K, Goodwin EC, et al. Senescence-associated ß-galactosidase is lysosomal ß-galactosidase. Aging Cell 2006; 5:187-95; PMID:16626397; http://dx.doi.org/10.1111/j.1474-9726. 2006.00199.x
    • (2006) Aging Cell , vol.5 , pp. 187-195
    • Lee, B.Y.1    Han, J.A.2    Im, J.S.3    Morrone, A.4    Johung, K.5    Goodwin, E.C.6
  • 20
    • 0033730616 scopus 로고    scopus 로고
    • Senescence-associated (ß)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells
    • PMID:11017877
    • Kurz DJ, Decary S, Hong Y, Erusalimsky JD. Senescence-associated (ß)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells. J Cell Sci 2000; 113:3613-22; PMID:11017877
    • (2000) J Cell Sci , vol.113 , pp. 3613-3622
    • Kurz, D.J.1    Decary, S.2    Hong, Y.3    Erusalimsky, J.D.4
  • 21
    • 26244445013 scopus 로고    scopus 로고
    • The limitations and validities of senescence associated-ß- galactosidase activity as an aging marker for human foreskin fibroblast Hs68 cells
    • PMID:16154306
    • Yang NC, Hu ML. The limitations and validities of senescence associated-ß-galactosidase activity as an aging marker for human foreskin fibroblast Hs68 cells. Exp Gerontol 2005; 40:813-9; PMID:16154306; http://dx.doi.org/10.1016/j.exger.2005.07.011
    • (2005) Exp Gerontol , vol.40 , pp. 813-819
    • Yang, N.C.1    Hu, M.L.2
  • 22
    • 0142217356 scopus 로고    scopus 로고
    • TGF-β cytokines increase senescence-associated beta-galactosidase activity in human prostate basal cells by supporting differentiation processes, but not cellular senescence
    • DOI 10.1016/j.exger.2003.08.008
    • Untergasser G, Gander R, Rumpold H, Heinrich E, Plas E, Berger P. TGF-beta cytokines increase senescence-associated beta-galactosidase activity in human prostate basal cells by supporting differentiation processes, but not cellular senescence. Exp Gerontol 2003; 38:1179-88; PMID:14580871; http://dx.doi.org/10.1016/j.exger.2003.08.008 (Pubitemid 37324429)
    • (2003) Experimental Gerontology , vol.38 , Issue.10 , pp. 1179-1188
    • Untergasser, G.1    Gander, R.2    Rumpold, H.3    Heinrich, E.4    Plas, E.5    Berger, P.6
  • 23
    • 0036203197 scopus 로고    scopus 로고
    • Markers of senescence?
    • DOI 10.1002/path.1073
    • Coates PJ. Markers of senescence? J Pathol 2002; 196:371-3; PMID:11920730; http://dx.doi.org/10.1002/path.1073 (Pubitemid 34262846)
    • (2002) Journal of Pathology , vol.196 , Issue.4 , pp. 371-373
    • Coates, P.J.1
  • 24
    • 0034713329 scopus 로고    scopus 로고
    • Is β-galactosidase staining a marker of senescence in vitro and in vivo?
    • DOI 10.1006/excr.2000.4875
    • Severino J, Allen RG, Balin S, Balin A, Cristofalo VJ. Is beta-galactosidase staining a marker of senescence in vitro and in vivo? Exp Cell Res 2000; 257:162-71; PMID:10854064; http://dx.doi.org/10.1006/excr.2000. 4875 (Pubitemid 30324654)
    • (2000) Experimental Cell Research , vol.257 , Issue.1 , pp. 162-171
    • Severino, J.1    Allen, R.G.2    Balin, S.3    Balin, A.4    Cristofalo, V.J.5
  • 25
    • 0032764992 scopus 로고    scopus 로고
    • Does pH 6 β-galactosidase activity indicate cell senescence?
    • DOI 10.1016/S0047-6374(99)00031-7, PII S0047637499000317
    • Krishna DR, Sperker B, Fritz P, Klotz U. Does pH 6 beta-galactosidase activity indicate cell senescence? Mech Ageing Dev 1999; 109:113-23; PMID:10515661; http://dx.doi.org/10.1016/S0047-6374(99)00031-7 (Pubitemid 29397514)
    • (1999) Mechanisms of Ageing and Development , vol.109 , Issue.2 , pp. 113-123
    • Krishna, D.R.1    Sperker, B.2    Fritz, P.3    Klotz, U.4
  • 26
    • 0032566278 scopus 로고    scopus 로고
    • Endogenous β-galactosidase activity in continuously nonproliferating cells
    • DOI 10.1006/excr.1998.4169
    • Yegorov YE, Akimov SS, Hass R, Zelenin AV, Prudovsky IA. Endogenous beta-galactosidase activity in continuously nonproliferating cells. Exp Cell Res 1998; 243:207-11; PMID:9716464; http://dx.doi.org/10.1006/excr.1998.4169 (Pubitemid 28397649)
    • (1998) Experimental Cell Research , vol.243 , Issue.1 , pp. 207-211
    • Yegorov, Y.E.1    Akimov, S.S.2    Hass, R.3    Zelenin, A.V.4    Prudovsky, I.A.5
  • 27
    • 84878852565 scopus 로고    scopus 로고
    • Colorimetric detection of senescence-associated ß galactosidase
    • PMID:23296655
    • Itahana K, Itahana Y, Dimri GP. Colorimetric detection of senescence-associated ß galactosidase. Methods Mol Biol 2013; 965:143-56; PMID:23296655; http://dx.doi.org/10.1007/978-1-62703-239-1-8
    • (2013) Methods Mol Biol , vol.965 , pp. 143-156
    • Itahana, K.1    Itahana, Y.2    Dimri, G.P.3
  • 28
    • 0025063976 scopus 로고
    • Inhibition of α-L-fucosidase by derivatives of deoxyfuconojirimycin and deoxymannojirimycin
    • Winchester B, Barker C, Baines S, Jacob GS, Namgoong SK, Fleet G. Inhibition of alpha-L-fucosidase by derivatives of deoxyfuconojirimycin and deoxymannojirimycin. Biochem J 1990; 265:277-82; PMID:2137330 (Pubitemid 20037700)
    • (1990) Biochemical Journal , vol.265 , Issue.1 , pp. 277-282
    • Winchester, B.1    Barker, C.2    Baines, S.3    Jacob, G.S.4    Namgoong, S.K.5    Fleet, G.6
  • 29
    • 36348971785 scopus 로고    scopus 로고
    • Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment
    • DOI 10.1182/blood-2007-02-073213
    • Janssen K, Pohlmann S, Jänicke RU, Schulze-Osthoff K, Fischer U. Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment. Blood 2007; 110:3662-72; PMID:17652622; http://dx.doi.org/10.1182/blood-2007-02-073213 (Pubitemid 350159635)
    • (2007) Blood , vol.110 , Issue.10 , pp. 3662-3672
    • Janssen, K.1    Pohlmann, S.2    Janicke, R.U.3    Schulze-Osthoff, K.4    Fischer, U.5
  • 31
    • 84874967976 scopus 로고    scopus 로고
    • Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues
    • PMID:23449538
    • Georgakopoulou EA, Tsimaratou K, Evangelou K, Fernandez Marcos PJ, Zoumpourlis V, Trougakos IP, et al. Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues. Aging (Albany NY) 2013; 5:37-50; PMID:23449538
    • (2013) Aging (Albany NY) , vol.5 , pp. 37-50
    • Georgakopoulou, E.A.1    Tsimaratou, K.2    Evangelou, K.3    Fernandez Marcos, P.J.4    Zoumpourlis, V.5    Trougakos, I.P.6
  • 32
    • 84868101237 scopus 로고    scopus 로고
    • Tumor suppression by p53 without apoptosis and senescence: Conundrum or rapalog-like gerosuppression?
    • PMID:22869016
    • Blagosklonny MV. Tumor suppression by p53 without apoptosis and senescence: Conundrum or rapalog-like gerosuppression? Aging (Albany NY) 2012; 4:450-5; PMID:22869016
    • (2012) Aging (Albany NY) , vol.4 , pp. 450-455
    • Blagosklonny, M.V.1
  • 35
    • 84857997408 scopus 로고    scopus 로고
    • A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
    • PMID:22343943
    • Settembre C, Zoncu R, Medina DL, Vetrini F, Erdin S, Erdin S, et al. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. EMBO J 2012; 31:1095-108; PMID:22343943; http://dx.doi.org/10. 1038/emboj.2012.32
    • (2012) EMBO J , vol.31 , pp. 1095-1108
    • Settembre, C.1    Zoncu, R.2    Medina, D.L.3    Vetrini, F.4    Erdin, S.5    Erdin, S.6
  • 36
    • 82855170875 scopus 로고    scopus 로고
    • TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy
    • PMID:22101272
    • Peña-Llopis S, Brugarolas J. TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy. Cell Cycle 2011; 10:3987-8; PMID:22101272; http://dx.doi.org/10.4161/cc.10.23.18251
    • (2011) Cell Cycle , vol.10 , pp. 3987-3988
    • Peña-Llopis, S.1    Brugarolas, J.2
  • 37
    • 84876090708 scopus 로고    scopus 로고
    • ZKSCAN3 is a master transcriptional repressor of autophagy
    • PMID:23434374
    • Chauhan S, Goodwin JG, Chauhan S, Manyam G, Wang J, Kamat AM, et al. ZKSCAN3 Is a Master Transcriptional Repressor of Autophagy. Mol Cell 2013; 50:16-28; PMID:23434374; http://dx.doi.org/10.1016/j.molcel.2013.01.024
    • (2013) Mol Cell , vol.50 , pp. 16-28
    • Chauhan, S.1    Goodwin, J.G.2    Chauhan, S.3    Manyam, G.4    Wang, J.5    Kamat, A.M.6
  • 38
    • 0032544449 scopus 로고    scopus 로고
    • Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
    • DOI 10.1016/S0092-8674(00)81732-8
    • Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA, Gruss P. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 1998; 94:727-37; PMID:9753320; http://dx.doi.org/10.1016/S0092-8674(00)81732-8 (Pubitemid 28436005)
    • (1998) Cell , vol.94 , Issue.6 , pp. 727-737
    • Cecconi, F.1    Alvarez-Bolado, G.2    Meyer, B.I.3    Roth, K.A.4    Gruss, P.5
  • 39
    • 79952303452 scopus 로고    scopus 로고
    • The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
    • PMID:21307310
    • Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, et al. The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci USA 2011; 108:3665-70; PMID:21307310; http://dx.doi.org/10. 1073/pnas.1019736108
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3665-3670
    • Meerbrey, K.L.1    Hu, G.2    Kessler, J.D.3    Roarty, K.4    Li, M.Z.5    Fang, J.E.6
  • 41
    • 0037119058 scopus 로고    scopus 로고
    • Expression of active human β-glucuronidase in Sf9 cells infected with recombinant baculovirus
    • DOI 10.1016/S0024-3205(02)01917-3, PII S0024320502019173
    • Sperker B, Mürdter TE, Backman JT, Fritz P, Kroemer HK. Expression of active human beta-glucuronidase in Sf9 cells infected with recombinant baculovirus. Life Sci 2002; 71:1547-57; PMID:12127909; http://dx.doi.org/10. 1016/S0024-3205(02)01917-3 (Pubitemid 34808717)
    • (2002) Life Sciences , vol.71 , Issue.13 , pp. 1547-1557
    • Sperker, B.1    Murdter, T.E.2    Backman, J.T.3    Fritz, P.4    Kroemer, H.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.