Resolution of omeprazole using coupled preferential crystallization: Efficient separation of a nonracemizable conglomerate salt under near-equilibrium conditions

Organic Process Research and Development

Volumn 17, Issue 6, 2013, Pages 946-950

  Hein, Jason E ^a   Cao, Blessing Huynh ^a   Van Der Meijden, Maarten W ^b   Leeman, Michel ^b   Kellogg, Richard M ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Syncom BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COMPETING PROCESS; CONTINUOUS PROCESS; ENANTIOPURE; OMEPRAZOLE; PREFERENTIAL CRYSTALLIZATION; PRIMARY NUCLEATION; SELECTIVE CRYSTALLIZATION; SMALL PERTURBATIONS;

CRYSTAL GROWTH;

EID: 84879358141     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op400081c     Document Type: Article

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