Ethanol-induced apoptosis in human liver adenocarcinoma cells (SK-Hep1): Fas- and mitochondria-mediated pathways and interaction with MAPK signaling system

Toxicology in Vitro

Volumn 27, Issue 6, 2013, Pages 1820-1829

  Morio, Yuri ^a   Tsuji, Mayumi ^a   Inagaki, Manami ^a   Nakagawa, Mai ^a   Asaka, Yuri ^a   Oyamada, Hideto ^a   Furuya, Kanji ^a   Oguchi, Katsuji ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

Alcoholic liver injury; Ethanol induced apoptosis; Fas; MAPK; ROS; SK Hep1 cells

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ALCOHOL; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL FATE; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CARCINOMA; MITOCHONDRION; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; SK HEP1 CELL;

ALCOHOLIC LIVER INJURY; ETHANOL-INDUCED APOPTOSIS; FAS; MAPK; ROS; SK-HEP1 CELLS;

ADENOCARCINOMA; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 8; CELL LINE, TUMOR; ETHANOL; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 84879357497     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.05.009     Document Type: Article

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