High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 25, 2013, Pages 10183-10188

  Müller, Roger ^a   Gräwert, Melissa A ^a,b   Kern, Thomas ^a,c   Madl, Tobias ^a,c,d   Peschek, Jirka ^a   Sattler, Michael ^a,c   Groll, Michael ^a   Buchner, Johannes ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b DESY   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UNIVERSITY OF GRAZ   (Austria)

Author keywords

Antibody oligomerization; Dimer interfaces; Hybrid approach

Indexed keywords

IMMUNOGLOBULIN M;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; COVALENT BOND; DIMERIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERIZATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; RADIATION SCATTERING; X RAY CRYSTALLOGRAPHY;

ANTIBODY OLIGOMERIZATION; DIMER INTERFACES; HYBRID APPROACH;

CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN M; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POLYMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84879317601     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1300547110     Document Type: Article

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