Investigation of anti-oxidative and anti-genotoxic effects of Origanum vulgare L. essential oil on human lymphocytes in vitro

Journal of Essential Oil-Bearing Plants

Volumn 15, Issue 6, 2012, Pages 997-1005

  Ceker, Selcuk ^a   Agar, Guleray ^b   Nardemir, Gokce ^b   Anar, Mustafa ^b   Kizil, Hamit Emre ^c   Alpsoy, Lokman ^d  

^a AGRI IBRAHIM CECEN UNIVERSITY   (Turkey)

^b ATATÜRK UNIVERSITY   (Turkey)

^c BAYBURT UNIVERSITY   (Turkey)

^d FATIH UNIVERSITY   (Turkey)

Author keywords

Aflatoxin B1; Anti genotoxicity; Antioxidant enzymes; Origanum vulgare

Indexed keywords

LAMIACEAE; ORIGANUM; ORIGANUM VULGARE;

EID: 84879315616     PISSN: 0972060X     EISSN: None     Source Type: Journal    
DOI: 10.1080/0972060X.2012.10662604     Document Type: Article

References (48)

1. Bruneton, J. (1999). Pharmacognosy, phytochemistry, in: Medicinal Plants: Essential Oils. 2nd ed. Lavoisier Publishing. New York.
2. Daferera, D.J., Ziogas, B.N. and Polissiou, M.G. (2003). The effectiveness of plant essential oils on the growth of Botrytis cinerea, Fusarium sp and Clavibacter michiganensis subsp michiganensis. Crop Protection. 22: 39-44.
3. Isman, M.B. (2000). Plant essential oils for pest and disease management. Crop Protection. 19: 603-608.
4. Sönmez, A. (1999). Denizli Yöresi Lokal Endemik Origanum hypericifolium Üzerinde Morfolojik, Anatomik ve Korolojik Çalý{thorn}malar, in Balýkkesir Üniversitesi Fen Bilimleri Enstitüsü, Balýkkesir Üniversitesi, Balýkesir
5. Anonymous. (2004). Establish Protocols and Guidelines for Table Olive Processing in Australia. A report for the Rural Industries Research and Development Corporation by Stanley George Kailis and David Harris. RIRDC Publication No. 04/136. RIRDC Project No, UWA 59A.
6. Tsinas AC. (1999). The Art of Origanum. Graýn Feed & Milling Technology: 25-26.
7. Lambert, R.J.W., Skandamis, P.N., Coote, P.J. and Nychas, G.J.E. (2001). A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. Journal of Applied Microbiology. 91: 453-462.
8. Sivropoulou, A., Papanikolaou, E., Nikolaou, C., Kokkini, S., Lanaras, T. and Arsenakis, M. (1996). Antimicrobial and cytotoxic activities of Origanum essential oils. Journal of Agricultural and Food Chemistry.44: 1202-1205.
9. Manohar, V., Ingram, C., Gray, J., Talpur, N.A., Echard, B.W., Bagchi, D. and Preuss H.G. (2001). Antifungal activities of origanum oil against Candida albicans. Molecular and Cellular Biochemistry. 228: 111-117.
10. Isman, M.B., Wan, A.J. and Passreiter, C.M. (2001). Insecticidal activity of essential oils to the tobacco cutworm, Spodoptera litura. Fitoterapia. 72: 65-68.
11. Kulisic, T., Radonic, A., Katalinic, V. and Milos, M. (2004). Use of different methods for testing antioxidative activity of oregano essential oil. Food Chemistry. 85: 633-640.
12. Puertas-Mejia, M., Hillebrand, S., Stashenko, E. and Winterhalter, P. (2002). In vitro radical scavenging activity of essential oils from Columbian plants and fractions from oregano (Origanum vulgare L.) essential oil. Flavour and Fragrance Journal. 17: 380-384.
13. Ruberto, G. and Baratta, M.T. (2000). Antioxidant activity of selected essential oil components in two lipid model systems. Food Chemistry 69: 167-174.
14. Vekiari, S.A., Oreopoulou, V., Tzia, C. and Thomopoulos, C.D. (1993). Oregano Flavonoids as Lipid Antioxidants. Journal of the American Oil Chemists Society. 70: 483-487.
15. Teissedre, P.L. and Waterhouse, A.L. (2000). Inhibition of oxidation of human low-density lipoproteins by phenolic substances in different essential oils varieties. Journal of Agricultural and Food Chemistry. 48: 3801-3805.
16. Lemhadri, A., Zeggwagh, N.A., Maghrani, M., Jouad, H. and Eddouks, M. (2004). Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. Journal of Ethnopharmacology. 92: 251-256.
17. Ozbek, T., Gulluce, M., Sahin, F., Ozkan, H., Sevsay, S. and Baris, O. (2008). Investigation of the Antimutagenic Potentials of the Methanol Extract of Origanum vulgare L. subsp vulgare in the Eastern Anatolia Region of Turkey. Turkish Journal of Biology. 32: 271-276.
18. Idaomar, M., Mezzoug, N., Elhadri, A., Dallouh, A., Amkiss, S., Skali, N.S., Abrini, J., Zhiri, A., Baudoux, D., Diallo, B. and El Jaziri, A. (2007). Investigation of the mutagenic and anti-mutagenic effects of Origanum compactum essential oil and some of its constituents. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 629: 100-110.
19. Ipek, E., Zeytinoglu, H., Okay, S., Tuylu, B.A., Kurkcuoglu, M. and Baser, K.H.C. (2005). Genotoxicity and antigenotoxicity of Origanum oil and carvacrol evaluated by Ames Salmonella/ microsomal test. Food Chemistry. 93: 551-556.
20. Bakkali, F, Averbeck, S., Averbeck, D., Zhiri, A. and Idaomar, A. (2005). Cytotoxicity and gene induction by some essential oils in the yeast Saccharomyces cerevisiae. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 585:1-13.
21. Garcia, M.A. and Sanz, J. (2001). Analysis of Origanum vulgare volatiles by direct thermal desorption coupled to gas chromatography-mass spectrometry. Journal of Chromatography A. 918: 189-194.
22. Sahin, A., Baylan, M., Sahinler, N., Canogullarý, S. and Gul, A. (2003). The effects on fattening performance and carcass properties of propolis in japanese quail II., in Proceedings of the Marmara Apiculture Congress, Yalova, Turkey, 212-212.
23. Sahin, F., Gulluce, M., Daferera, D., Sokmen, A., Sokmen, M., Polissiou, M., Agar, G. and Ozer, H. (2004). Biological activities of the essential oils and methanol extract of Origanum vulgare ssp vulgare in the Eastern Anatolia region of Turkey. Food Control. 15: 549-557.
24. Hersch-Martinez, P., Leanos-Miranda, B.E. and Solorzano-Santos F. (2005). Antibacterial effects of comm,ercial essential oils over locally prevalent pathogenic strains in Mexico. Fitoterapia. 76: 453-457.
25. Perry, P. and Evans, H.J. (1975). Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange. Nature. 258: 121-125.
26. Countryman, P.I. and Heddle, J.A. (1976). Production of Micronuclei from Chromosome-Aberrations in Irradiated Cultures of Human Lymphocytes. Mutation Research. 41: 321-331.
27. Anderson, I.B., Mullen, W.H., Meeker, J.E., Khojasteh Bakht, S.C., Oishi, S., Nelson, S.D. and Blanc, P.D. (1996). Pennyroyal toxicity: measurement of toxic metabolite levels in two cases and review of the literature. Ann Intern Med. 124: 726-734.
28. Ohkawa, H., Ohishi, N. and Yagi, K. (1979). Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 95: 351-358.
29. Sun, Y., Oberley, L.W. and Li, Y. (1988). A simple method for clinical assay of superoxide dismutase. Clin Chem.34: 497-500.
30. Paglia, D.E. and Valentine, W.N. (1967). Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 70: 158-169.
31. Tietze, F. (1969). Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem. 27: 502-522.
32. Ohkawa, H., Ohishi, N. and Yagi, K. (1979). Assay for Lipid Peroxides in Animal-Tissues by Thiobarbituric Acid Reaction. Analytical Biochemistry. 95: 351-358.
33. Bradford, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72: 248-254.
34. Komali, A.S., Zheng, Z.X. and Shetty, K. (1999). A mathematical model for the growth kinetics and synthesis of phenolics in oregano (Origanum vulgare) shoot cultures inoculated with Pseudomonas species. Process Biochemistry. 35: 227-235.
35. da Costa, A.C., dos Santos, B.H.C., Santos, L. and Lima, E.D. (2009). Antibacterial activity of the essential oil of Origanum vulgare L. (Lamiaceae) against bacterial multiresistant strains isolated from nosocomial patients. Revista Brasileira De Farmacognosia-Brazilian Journal of Pharmacognosy. 19: 236-241.
36. Azaz, A.D., Esen, G., Kurkcuoglu, M., Baser, K.H.C. and Tinmaz, A. (2007). Essential oil and antimicrobial activity of wild and cultivated Origanum vulgare L. subsp hirtum (Link) letswaart from the Marmara region, Turkey. Flavour and Fragrance Journal. 22: 371-376.
37. Baher, Z.F., Mirza, M., Ghorbanli, M. and Rezaii, M.B. (2002). The influence of water stress on plant height, herbal and essential oil yield and composition in Satureja hortensis L. Flavour and Fragrance Journal. 17: 275-277.
38. Gulluce, M., Sokmen, M., Daferera, D., Agar, G., Ozkan, H., Kartal, N., Polissiou, M., Sokmen, A. and Sahin, F. (2003). In vitro antibacterial, antifungal, and antioxidant activities of the essential oil and methanol extracts of herbal parts and callus cultures of Satureja hortensis L. Journal of Agricultural and Food Chemistry. 51: 3958-3965.
39. Milos, M., Radonic, A., Bezic, N. and Dunkic, V. (2001). Localities and seasonal variations in the chemical composition of essential oils of Satureja montana L. and S. cuneifolia Ten. Flavour and Fragrance Journal. 16: 157-160.
40. Mazzanti, G., Di Sotto, A. and Evandri, M.G. (2008). Antimutagenic and mutagenic activities of some terpenes in the bacterial reverse mutation assay. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 653: 130-133.
41. Zheng, G.Q., Kenney, P.M. and Lam, L.K.T. (1992). Sesquiterpenes from Clove (Eugenia-Caryophyllata) as Potential Anticarcinogenic Agents. Journal of Natural Products. 55: 999-1003.
42. Ilhan, S., Erdemgil, F.Z., Korkmaz, F., Kaplan, C., Mercangoz, A., Arfan, M. and Ahmad, S. (2007). Chemical composition and biological activity of the essential oil of Perovskia atriplicifolia from Pakistan. Pharmaceutical Biology. 45: 324-331.
43. Madrigal-Bujaidar, E., Carino-Cortes, R., Hernandez-Ceruelos, A., Torres-Valencia, J.M., Gonzalez-Avila, A. and Arriaga-Alba, M. (2007). Antimutagenicity of Stevia pilosa and Stevia eupatoria evaluated with the Ames test. Toxicology in Vitro. 21: 691-697.
44. Mazzanti, G., Di Sotto, A., Carbone, F., Hrelia, P. and Maffei, F. (2010). Inhibition by beta-caryophyllene of ethyl methanesulfonate-induced clastogenicity in cultured human lymphocytes. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 699: 23-28.
45. Madrigal-Bujaidar, E., Molina-Jasso, D. and Alvarez-Gonzalez, I. (2009). Clastogenicity of Beta-Caryophyllene in Mouse. Biological & Pharmaceutical Bulletin. 32: 520-522.
46. Halici, M., Odabasoglu, F., Suleyman, H., Cakir, A., Aslan, A. and Bayir, Y. (2005). Effects of water extract of Usnea longissima on antioxidant enzyme activity and mucosal damage caused by indomethacin in rats. Phytomedicine. 12: 656-662.
47. Odabasoglu, F., Aslan, A., Cakir, A., Suleyman, H., Karagoz, Y., Halici, M. and Bayir, Y. (2004). Comparison of antioxidant activity and phenolic content of three lichen species. Phytother Res. 18: 938-941.
48. Russo, A., Bonina, E., Acquaviva, R., Campisi, A., Galvano, F., Ragusa, N. and Vanella, A. (2002). Red orange extract: Effect on DNA cleavage. Journal of Food Science. 67: 2814-2818.