Suspended microfluidics

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 25, 2013, Pages 10111-10116

  Casavant, Benjamin P ^a,b   Berthier, Erwin ^a,b,c   Theberge, Ashleigh B ^a,b,c   Berthier, Jean ^b   Montanez Sauri, Sara I ^a,d   Bischel, Lauren L ^a,b   Brakke, Kenneth ^e   Hedman, Curtis J ^f   Bushman, Wade ^a,c   Keller, Nancy P ^c   Beebe, David J ^a,b  

^a UNIVERSITY OF WISCONSIN   (United States)

^b University of Wisconsin Madison   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d DIF   (France)

^e SUSQUEHANNA UNIVERSITY   (United States)

^f UNIVERSITY OF WISCONSIN   (United States)

Author keywords

Arrayed migration platform; High throughput metabolomics; Multiplexed cell culture; Passive biphasic systems; Spontaneous capillary flow

Indexed keywords

COLLAGEN; ILOMASTAT;

ARTICLE; CAPILLARY; CARCINOMA CELL; CELL CULTURE; CELL GROWTH; CONTROLLED STUDY; FLUID FLOW; MICROARRAY ANALYSIS; MICROFLUIDICS; PRIORITY JOURNAL; SURFACE TENSION;

ARRAYED MIGRATION PLATFORM; HIGH THROUGHPUT METABOLOMICS; MULTIPLEXED CELL CULTURE; PASSIVE BIPHASIC SYSTEMS; SPONTANEOUS CAPILLARY FLOW;

ADRENAL CORTEX; BREAST NEOPLASMS; CAPILLARIES; CELL BIOLOGY; CELL LINE, TUMOR; CELL MEMBRANE; CELL MOVEMENT; COLLAGEN TYPE I; COMPUTER SIMULATION; FEMALE; HUMANS; HYDROCORTISONE; MALE; MATRIX METALLOPROTEINASE INHIBITORS; METABOLOMICS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROFLUIDICS; MODELS, BIOLOGICAL; PROSTATIC NEOPLASMS; STEROIDS; TOXICOLOGY;

CALLITHRIX;

EID: 84879291876     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302566110     Document Type: Article

References (29)

1. Zhao B, Moore JS, Beebe DJ (2001) Surface-directed liquid flow inside microchannels. Science 291(5506):1023-1026.
2. Atencia J, Beebe DJ (2005) Controlled microfluidic interfaces. Nature 437(7059):648-655.
3. Agresti JJ, et al. (2010) Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proc Natl Acad Sci USA 107(9):4004-4009.
4. Berry SM, Alarid ET, Beebe DJ (2011) One-step purification of nucleic acid for gene expression analysis via Immiscible Filtration Assisted by Surface Tension (IFAST). Lab Chip 11(10):1747-1753.
5. Huh D, et al. (2010) Reconstituting organ-level lung functions on a chip. Science 328(5986):1662-1668.
6. Repesh LA (1989) A new in vitro assay for quantitating tumor cell invasion. Invasion Metastasis 9(3):192-208.
7. Mary P, Studer V, Tabeling P (2008) Microfluidic droplet-based liquid-liquid extraction. Anal Chem 80(8):2680-2687.
8. Beebe DJ, et al. (2000) Functional hydrogel structures for autonomous flow control inside microfluidic channels. Nature 404(6778):588-590.
9. Song S, Singh AK, Shepodd TJ, Kirby BJ (2004) Microchip dialysis of proteins using in situ photopatterned nanoporous polymer membranes. Anal Chem 76(8):2367-2373.
10. Berthier J, et al. (2009) On the pinning of interfaces on micropillar edges. J Colloid Interface Sci 338(1):296-303.
11. Lee SH, et al. (2010) Capillary based patterning of cellular communities in laterally open channels. Anal Chem 82(7):2900-2906.
12. Wong AP, Perez-Castillejos R, Christopher Love J, Whitesides GM (2008) Partitioning microfluidic channels with hydrogel to construct tunable 3-D cellular microenvironments. Biomaterials 29(12):1853-1861.
13. Hong JW, Quake SR (2003) Integrated nanoliter systems. Nat Biotechnol 21(10):1179-1183.
14. Paguirigan AL, Beebe DJ (2008) Microfluidics meet cell biology: Bridging the gap by validation and application of microscale techniques for cell biological assays. Bioessays 30(9):811-821.
15. Hsu C-H, Chen C, Folch A (2004) "Microcanals" for micropipette accessto single cells in microfluidic environments. Lab Chip 4(5):420-424.
16. Olofsson J, et al. (2004) A microfluidics approach to the problem of creating separate solution environments accessible from macroscopic volumes. Anal Chem 76(17):4968-4976.
17. Gau H, Herminghaus S, Lenz P, Lipowsky R (1999) Liquid morphologies on structured surfaces: from microchannels to microchips. Science 283(5398):46-49.
18. Seemann R, Brinkmann M, Kramer EJ, Lange FF, Lipowsky R (2005) Wetting morphologies at microstructured surfaces. Proc Natl Acad Sci USA 102(6):1848-1852.
19. Fernandes TG, Diogo MM, Clark DS, Dordick JS, Cabral J M S (2009) High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research. Trends Biotechnol 27(6):342-349.
20. Sardesai NP, Kadimisetty K, Faria R, Rusling JF (2013) A microfluidic electrochemiluminescent device for detecting cancer biomarker proteins. Anal Bioanal Chem 405(11):3831-3838.
21. Keenan TM, Frevert CW, Wu A, Wong V, Folch A (2010) A new method for studying gradient-induced neutrophil desensitization based on an open microfluidic chamber. Lab Chip 10(1):116-122.
22. Oliveira NM, Neto AI, Song W, Mano JF (2010) Two-dimensional open microfluidic devices by tuning the wettability on patterned superhydrophobic polymeric surface. Appl Phys Express 3:085205.
23. Melin J, van der Wijngaart W, Stemme G (2005) Behaviour and design considerations for continuous flow closed-open-closed liquid microchannels. Lab Chip 5(6):682-686.
24. Concus P, Finn R (1969) On the behavior of a capillary surface in a wedge. Proc Natl Acad Sci USA 63(2):292-299.
25. Weigelt B, Lo AT, Park CC, Gray JW, Bissell MJ (2010) HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat 122(1):35-43.
26. Scott HM, Mason JI, Sharpe RM (2009) Steroidogenesis in the fetal testis and its susceptibility to disruption by exogenous compounds. Endocr Rev 30(7):883-925.
27. Locke JA, et al. (2008) Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 68(15):6407-6415.
28. Brakke KA (1992) The Surface Evolver. Exp Mat 1:141-165.
29. Babu PS, Bavers DL, Shah S, Hammer GD (2000) Role of phosphorylation, gene dosage and Dax-1 in SF-1 mediated steroidogenesis. Endocr Res 26(4):985-994. Innovation-MIKS