Epitope Mapping for Monoclonal Antibody Reveals the Activation Mechanism for αVβ3 Integrin

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Kamata, Tetsuji ^a   Handa, Makoto ^a   Takakuwa, Sonomi ^a   Sato, Yukiko ^a   Kawai, Yohko ^b   Ikeda, Yasuo ^c   Aiso, Sadakazu ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^c WASEDA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE; FIBRINOGEN; MONOCLONAL ANTIBODY; SERINE; VITRONECTIN RECEPTOR;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING SITE; CHIMERA; CONTROLLED STUDY; CRYSTAL STRUCTURE; EPITOPE MAPPING; LEG; LIGAND BINDING; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; CHO CELLS; CRICETINAE; CRICETULUS; EPITOPE MAPPING; FIBRINOGEN; HUMANS; INTEGRIN ALPHAVBETA3; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84879274962     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066096     Document Type: Article

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