메뉴 건너뛰기




Volumn 113, Issue 7, 2013, Pages 1695-1704

Hyperoxia but not ambient pressure decreases tetrahydrobiopterin level without affecting the enzymatic capability of nitric oxide synthase in human endothelial cells

Author keywords

Diving; Endothelial cells; Glutathione; Heat shock protein 70; Nitric oxide synthase; Tetrahydrobiopterin

Indexed keywords

5,6,7,8-TETRAHYDROBIOPTERIN; BIOPTERIN; DRUG DERIVATIVE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; HEAT SHOCK PROTEIN 70; NITRIC OXIDE; OXYGEN; TETRAHYDROBIOPTERIN;

EID: 84879245006     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-013-2595-x     Document Type: Article
Times cited : (10)

References (45)
  • 1
    • 1542283780 scopus 로고    scopus 로고
    • Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease
    • 14656731 10.1161/01.ATV.0000110785.96039.f6 1:CAS:528: DC%2BD2cXhvFOisrk%3D
    • Alp NJ, Channon KM (2004) Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease. Arterioscler Thromb Vasc Biol 24:413-420
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 413-420
    • Alp, N.J.1    Channon, K.M.2
  • 2
    • 0035965550 scopus 로고    scopus 로고
    • Effect of DL-alpha-lipoic acid on mitochondrial enzymes in aged rats
    • 11672700 10.1016/S0009-2797(01)00268-X 1:CAS:528:DC%2BD3MXnsleku78%3D
    • Arivazhagan P, Ramanathan K, Panneerselvam C (2001) Effect of DL-alpha-lipoic acid on mitochondrial enzymes in aged rats. Chem Biol Interact 138:189-198
    • (2001) Chem Biol Interact , vol.138 , pp. 189-198
    • Arivazhagan, P.1    Ramanathan, K.2    Panneerselvam, C.3
  • 3
    • 0035120543 scopus 로고    scopus 로고
    • Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells
    • 11243424 10.1097/00005344-200103000-00012 1:CAS:528:DC%2BD3MXhs1ShsLY%3D
    • Baker TA, Milstien S, Katusic ZS (2001) Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells. J Cardiovasc Pharmacol 37:333-338
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 333-338
    • Baker, T.A.1    Milstien, S.2    Katusic, Z.S.3
  • 4
    • 57149090082 scopus 로고    scopus 로고
    • Predive sauna and venous gas bubbles upon decompression from 400 kPa
    • 19070305 10.3357/ASEM.2377.2008
    • Blatteau JE, Gempp E, Balestra C, Mets T, Germonpre P (2008) Predive sauna and venous gas bubbles upon decompression from 400 kPa. Aviat Space Environ Med 79:1100-1105
    • (2008) Aviat Space Environ Med , vol.79 , pp. 1100-1105
    • Blatteau, J.E.1    Gempp, E.2    Balestra, C.3    Mets, T.4    Germonpre, P.5
  • 6
    • 77955655985 scopus 로고    scopus 로고
    • Endothelium and diving
    • W.C. Aird (eds) Cambridge University Press Cambridge 10.1017/ CBO9780511546198.056
    • Brubakk AO, Eftedal OS, Wisløff U (2007) Endothelium and diving. In: Aird WC (ed) Endothelial biomedicine. Cambridge University Press, Cambridge, pp 497-505
    • (2007) Endothelial Biomedicine , pp. 497-505
    • Brubakk, A.O.1    Eftedal, O.S.2    Wisløff, U.3
  • 7
    • 34547093890 scopus 로고    scopus 로고
    • Methods to detect nitric oxide and its metabolites in biological samples
    • 17664129 10.1016/j.freeradbiomed.2007.04.026 1:CAS:528: DC%2BD2sXotlSms7o%3D
    • Bryan NS, Grisham MB (2007) Methods to detect nitric oxide and its metabolites in biological samples. Free Radic Biol Med 43:645-657
    • (2007) Free Radic Biol Med , vol.43 , pp. 645-657
    • Bryan, N.S.1    Grisham, M.B.2
  • 8
    • 80054803967 scopus 로고    scopus 로고
    • Bronchial nitric oxide flux and alveolar nitric oxide concentration after exposure to hyperoxia
    • 21961398 10.3357/ASEM.2995.2011 1:CAS:528:DC%2BC3MXhtlGjurfJ
    • Caspersen C, Stensrud T, Thorsen E (2011) Bronchial nitric oxide flux and alveolar nitric oxide concentration after exposure to hyperoxia. Aviat Space Environ Med 82:946-950
    • (2011) Aviat Space Environ Med , vol.82 , pp. 946-950
    • Caspersen, C.1    Stensrud, T.2    Thorsen, E.3
  • 9
    • 41849144894 scopus 로고    scopus 로고
    • Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS
    • 18192221 10.1152/ajpheart.00823.2007 1:CAS:528:DC%2BD1cXkvVyltLs%3D
    • Crabtree MJ, Smith CL, Lam G, Goligorsky MS, Gross SS (2008) Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS. Am J Physiol Heart Circ Physiol 294:H1530-H1540
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Crabtree, M.J.1    Smith, C.L.2    Lam, G.3    Goligorsky, M.S.4    Gross, S.S.5
  • 10
    • 0025975010 scopus 로고
    • Modulation of glutathione content and the effect on methionine auxotrophy and cellular distribution of homocysteine and cysteine in mouse cell lines
    • 1995190 10.1093/carcin/12.2.241 1:CAS:528:DyaK3MXhtF2ms78%3D
    • Djurhuus R, Svardal AM, Mansoor MA, Ueland PM (1991) Modulation of glutathione content and the effect on methionine auxotrophy and cellular distribution of homocysteine and cysteine in mouse cell lines. Carcinogenesis 12:241-247
    • (1991) Carcinogenesis , vol.12 , pp. 241-247
    • Djurhuus, R.1    Svardal, A.M.2    Mansoor, M.A.3    Ueland, P.M.4
  • 11
    • 0033144176 scopus 로고    scopus 로고
    • Glutathione in the cellular defense of human lung cells exposed to hyperoxia and high pressure
    • 10372426 1:CAS:528:DyaK1MXktFels7c%3D
    • Djurhuus R, Svardal AM, Thorsen E (1999) Glutathione in the cellular defense of human lung cells exposed to hyperoxia and high pressure. Undersea Hyperb Med 26:75-85
    • (1999) Undersea Hyperb Med , vol.26 , pp. 75-85
    • Djurhuus, R.1    Svardal, A.M.2    Thorsen, E.3
  • 12
    • 77955663792 scopus 로고    scopus 로고
    • Simulated diving after heat stress potentiates the induction of heat shock protein 70 and elevates glutathione in human endothelial cells
    • 19924566 10.1007/s12192-009-0156-3 1:CAS:528:DC%2BC3cXntlKqu78%3D
    • Djurhuus R, Nossum V, Lundsett N, Hovin W, Svardal AM, Havnes MB, Fismen L, Hjelde A, Brubakk AO (2010) Simulated diving after heat stress potentiates the induction of heat shock protein 70 and elevates glutathione in human endothelial cells. Cell Stress Chaperones 15:405-414
    • (2010) Cell Stress Chaperones , vol.15 , pp. 405-414
    • Djurhuus, R.1    Nossum, V.2    Lundsett, N.3    Hovin, W.4    Svardal, A.M.5    Havnes, M.B.6    Fismen, L.7    Hjelde, A.8    Brubakk, A.O.9
  • 14
    • 84866699290 scopus 로고    scopus 로고
    • Simultaneous quantification of tetrahydrobiopterin, dihydrobiopterin and biopterin by liquid chromatography coupled electrospray tandem mass spectrometry
    • 22940649 10.1016/j.ab.2012.08.019 1:CAS:528:DC%2BC38XhsFWiurzL
    • Fismen L, Eide T, Djurhuus R, Svardal AM (2012a) Simultaneous quantification of tetrahydrobiopterin, dihydrobiopterin and biopterin by liquid chromatography coupled electrospray tandem mass spectrometry. Anal Biochem 430:163-170
    • (2012) Anal Biochem , vol.430 , pp. 163-170
    • Fismen, L.1    Eide, T.2    Djurhuus, R.3    Svardal, A.M.4
  • 15
    • 84864719560 scopus 로고    scopus 로고
    • Differential effects on nitric oxide synthase, heat shock proteins and glutathione in human endothelial cells exposed to heat stress and simulated diving
    • 22113731 10.1007/s00421-011-2241-4 1:CAS:528:DC%2BC38XosFCku7c%3D
    • Fismen L, Hjelde A, Svardal AM, Djurhuus R (2012b) Differential effects on nitric oxide synthase, heat shock proteins and glutathione in human endothelial cells exposed to heat stress and simulated diving. Eur J Appl Physiol 112:2717-2725
    • (2012) Eur J Appl Physiol , vol.112 , pp. 2717-2725
    • Fismen, L.1    Hjelde, A.2    Svardal, A.M.3    Djurhuus, R.4
  • 17
    • 84879411566 scopus 로고    scopus 로고
    • Effect of tetrahydrobiopterin and exercise training on endothelium-dependent vasorelaxation in SHR
    • 10.1007/s13105-012-0210-y 23011782
    • Guerrero F, Thioub S, Goanvec C, Theunissen S, Feray A, Balestra C, Mansourati J (2012) Effect of tetrahydrobiopterin and exercise training on endothelium-dependent vasorelaxation in SHR. J Physiol Biochem. doi: 10.1007/s13105-012-0210-y
    • (2012) J Physiol Biochem
    • Guerrero, F.1    Thioub, S.2    Goanvec, C.3    Theunissen, S.4    Feray, A.5    Balestra, C.6    Mansourati, J.7
  • 18
    • 0031030853 scopus 로고    scopus 로고
    • Glutathione regulates nitric oxide synthase in cultured hepatocytes
    • 8998123 10.1097/00000658-199701000-00009 1:STN:280:DyaK2s7lt1Wqsw%3D%3D
    • Harbrecht BG, Di Silvio M, Chough V, Kim YM, Simmons RL, Billiar TR (1997) Glutathione regulates nitric oxide synthase in cultured hepatocytes. Ann Surg 225:76-87
    • (1997) Ann Surg , vol.225 , pp. 76-87
    • Harbrecht, B.G.1    Di Silvio, M.2    Chough, V.3    Kim, Y.M.4    Simmons, R.L.5    Billiar, T.R.6
  • 19
    • 0038000633 scopus 로고    scopus 로고
    • Heat-induced increases in endothelial NO synthase expression and activity and endothelial NO release
    • 12663266 1:CAS:528:DC%2BD3sXlsFGitbo%3D
    • Harris MB, Blackstone MA, Ju H, Venema VJ, Venema RC (2003) Heat-induced increases in endothelial NO synthase expression and activity and endothelial NO release. Am J Physiol Heart Circ Physiol 285:H333-H340
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Harris, M.B.1    Blackstone, M.A.2    Ju, H.3    Venema, V.J.4    Venema, R.C.5
  • 20
    • 0035808310 scopus 로고    scopus 로고
    • L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin
    • 11022034 10.1074/jbc.M004392200 1:CAS:528:DC%2BD3MXmtV2rtQ%3D%3D
    • Heller R, Unbehaun A, Schellenberg B, Mayer B, Werner-Felmayer G, Werner ER (2001) l-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin. J Biol Chem 276:40-47
    • (2001) J Biol Chem , vol.276 , pp. 40-47
    • Heller, R.1    Unbehaun, A.2    Schellenberg, B.3    Mayer, B.4    Werner-Felmayer, G.5    Werner, E.R.6
  • 21
    • 0034625391 scopus 로고    scopus 로고
    • Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin
    • 10749876 10.1074/jbc.M002248200 1:CAS:528:DC%2BD3cXktFaks7c%3D
    • Huang A, Vita JA, Venema RC, Keaney JF Jr (2000) Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin. J Biol Chem 275:17399-17406
    • (2000) J Biol Chem , vol.275 , pp. 17399-17406
    • Huang, A.1    Vita, J.A.2    Venema, R.C.3    Keaney Jr., J.F.4
  • 22
    • 0034891330 scopus 로고    scopus 로고
    • Contrasting effects of thiol-modulating agents on endothelial NO bioactivity
    • 11443071 1:CAS:528:DC%2BD3MXlvFylsro%3D
    • Huang A, Xiao H, Samii JM, Vita JA, Keaney JF Jr (2001) Contrasting effects of thiol-modulating agents on endothelial NO bioactivity. Am J Physiol Cell Physiol 281:C719-C725
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Huang, A.1    Xiao, H.2    Samii, J.M.3    Vita, J.A.4    Keaney Jr., J.F.5
  • 23
    • 0037378425 scopus 로고    scopus 로고
    • Heat stress attenuates air bubble-induced acute lung injury: A novel mechanism of diving acclimatization
    • 12482763 10.1063/1.1586981
    • Huang KL, Wu CP, Chen YL, Kang BH, Lin YC (2003) Heat stress attenuates air bubble-induced acute lung injury: a novel mechanism of diving acclimatization. J Appl Physiol 94:1485-1490
    • (2003) J Appl Physiol , vol.94 , pp. 1485-1490
    • Huang, K.L.1    Wu, C.P.2    Chen, Y.L.3    Kang, B.H.4    Lin, Y.C.5
  • 24
    • 78649471694 scopus 로고    scopus 로고
    • Maintenance of cellular tetrahydrobiopterin homeostasis
    • 20846489 10.5483/BMBRep.2010.43.9.584 1:CAS:528:DC%2BC3cXhtlCktbnO
    • Kim HL, Park YS (2010) Maintenance of cellular tetrahydrobiopterin homeostasis. BMB Rep 43:584-592
    • (2010) BMB Rep , vol.43 , pp. 584-592
    • Kim, H.L.1    Park, Y.S.2
  • 25
    • 0032228255 scopus 로고    scopus 로고
    • Measurement of NOS activity by conversion of radiolabeled arginine to citrulline using ion-exchange separation
    • 10906994 1:CAS:528:DyaK1cXjslersL0%3D
    • Knowles R, Salter M (1998) Measurement of NOS activity by conversion of radiolabeled arginine to citrulline using ion-exchange separation. Methods Mol Biol 100:67-73
    • (1998) Methods Mol Biol , vol.100 , pp. 67-73
    • Knowles, R.1    Salter, M.2
  • 26
    • 0034820972 scopus 로고    scopus 로고
    • Endothelium-dependent vasorelaxation in inhibited by in vivo depletion of vascular thiol levels: Role of endothelial nitric oxide synthase
    • 11697135 10.1080/10715760100300901 1:CAS:528:DC%2BD3MXntVGqtLc%3D
    • Laursen JB, Boesgaard S, Trautner S, Rubin I, Poulsen HE, Aldershvile J (2001) Endothelium-dependent vasorelaxation in inhibited by in vivo depletion of vascular thiol levels: role of endothelial nitric oxide synthase. Free Radic Res 35:387-394
    • (2001) Free Radic Res , vol.35 , pp. 387-394
    • Laursen, J.B.1    Boesgaard, S.2    Trautner, S.3    Rubin, I.4    Poulsen, H.E.5    Aldershvile, J.6
  • 27
    • 0027262648 scopus 로고
    • Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans
    • 8319355 10.1161/01.CIR.88.1.43 1:STN:280:DyaK3szgs1ygsw%3D%3D
    • Lefroy DC, Crake T, Uren NG, Davies GJ, Maseri A (1993) Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans. Circulation 88:43-54
    • (1993) Circulation , vol.88 , pp. 43-54
    • Lefroy, D.C.1    Crake, T.2    Uren, N.G.3    Davies, G.J.4    Maseri, A.5
  • 28
    • 65049089113 scopus 로고    scopus 로고
    • Regulation of glutathione synthesis
    • 18601945 10.1016/j.mam.2008.05.005 1:CAS:528:DC%2BD1MXltFelu78%3D
    • Lu SC (2009) Regulation of glutathione synthesis. Mol Aspects Med 30:42-59
    • (2009) Mol Aspects Med , vol.30 , pp. 42-59
    • Lu, S.C.1
  • 29
    • 17344371325 scopus 로고    scopus 로고
    • Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation
    • 9409284 10.1161/01.ATV.17.11.2975 1:CAS:528:DyaK1cXisV2hug%3D%3D
    • Lynch SM, Frei B, Morrow JD, Roberts LJ 2nd, Xu A, Jackson T, Reyna R, Klevay LM, Vita JA, Keaney JF Jr (1997) Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation. Arterioscler Thromb Vasc Biol 17:2975-2981
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2975-2981
    • Lynch, S.M.1    Frei, B.2    Morrow, J.D.3    Roberts II, L.J.4    Xu, A.5    Jackson, T.6    Reyna, R.7    Klevay, L.M.8    Vita, J.A.9    Keaney Jr., J.F.10
  • 30
    • 0026515778 scopus 로고
    • Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma
    • 1632485 10.1016/0003-2697(92)90456-H 1:CAS:528:DyaK38XhtVajsrw%3D
    • Mansoor MA, Svardal AM, Ueland PM (1992) Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma. Anal Biochem 200:218-229
    • (1992) Anal Biochem , vol.200 , pp. 218-229
    • Mansoor, M.A.1    Svardal, A.M.2    Ueland, P.M.3
  • 32
    • 58249110563 scopus 로고    scopus 로고
    • Heat shock increases survival in rats exposed to hyperbaric pressure
    • 22692750
    • Medby C, Bye A, Wisløff U, Brubakk AO (2008) Heat shock increases survival in rats exposed to hyperbaric pressure. Diving Hyperb Med 38:189-193
    • (2008) Diving Hyperb Med , vol.38 , pp. 189-193
    • Medby, C.1    Bye, A.2    Wisløff, U.3    Brubakk, A.O.4
  • 33
    • 0028263767 scopus 로고
    • Glutathione-ascorbic acid antioxidant system in animals
    • 8144521 1:CAS:528:DyaK2cXis1Kns7k%3D
    • Meister A (1994) Glutathione-ascorbic acid antioxidant system in animals. J Biol Chem 269:9397-9400
    • (1994) J Biol Chem , vol.269 , pp. 9397-9400
    • Meister, A.1
  • 35
    • 69249222525 scopus 로고    scopus 로고
    • Do sauna therapy and exercise act by raising the availability of tetrahydrobiopterin?
    • 19581054 10.1016/j.mehy.2009.03.058 1:CAS:528:DC%2BD1MXhtVKntrfE
    • Pall ML (2009) Do sauna therapy and exercise act by raising the availability of tetrahydrobiopterin? Med Hypotheses 73:610-613
    • (2009) Med Hypotheses , vol.73 , pp. 610-613
    • Pall, M.L.1
  • 36
    • 0001599370 scopus 로고
    • Role of endothelium-derived nitric oxide in the regulation of blood pressure
    • 2497467 10.1073/pnas.86.9.3375 1:CAS:528:DyaL1MXit12hsbo%3D
    • Rees DD, Palmer RM, Moncada S (1989) Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci USA 86:3375-3378
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3375-3378
    • Rees, D.D.1    Palmer, R.M.2    Moncada, S.3
  • 37
    • 0036634864 scopus 로고    scopus 로고
    • Vitamin C matters: Increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid
    • 12039848 1:CAS:528:DC%2BD38XltlChur8%3D
    • Smith AR, Visioli F, Hagen TM (2002) Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid. FASEB J 16:1102-1104
    • (2002) FASEB J , vol.16 , pp. 1102-1104
    • Smith, A.R.1    Visioli, F.2    Hagen, T.M.3
  • 38
    • 0025360194 scopus 로고
    • FAD and GSH participate in macrophage synthesis of nitric oxide
    • 1692211 10.1016/0006-291X(90)92357-6 1:CAS:528:DyaK3cXktVant7k%3D
    • Stuehr DJ, Kwon NS, Nathan CF (1990) FAD and GSH participate in macrophage synthesis of nitric oxide. Biochem Biophys Res Commun 168:558-565
    • (1990) Biochem Biophys Res Commun , vol.168 , pp. 558-565
    • Stuehr, D.J.1    Kwon, N.S.2    Nathan, C.F.3
  • 39
    • 0025100797 scopus 로고
    • Determination of reduced, oxidized, and protein-bound glutathione in human plasma with precolumn derivatization with monobromobimane and liquid chromatography
    • 2327578 10.1016/0003-2697(90)90691-2 1:CAS:528:DyaK3cXhslGjs7s%3D
    • Svardal AM, Mansoor MA, Ueland PM (1990) Determination of reduced, oxidized, and protein-bound glutathione in human plasma with precolumn derivatization with monobromobimane and liquid chromatography. Anal Biochem 184:338-346
    • (1990) Anal Biochem , vol.184 , pp. 338-346
    • Svardal, A.M.1    Mansoor, M.A.2    Ueland, P.M.3
  • 40
    • 84861321238 scopus 로고    scopus 로고
    • Connecting the chemical and biological properties of nitric oxide
    • 22449080 10.1021/tx300042g 1:CAS:528:DC%2BC38XksVeksLY%3D
    • Toledo JC Jr, Augusto O (2012) Connecting the chemical and biological properties of nitric oxide. Chem Res Toxicol 25:975-989
    • (2012) Chem Res Toxicol , vol.25 , pp. 975-989
    • Toledo Jr., J.C.1    Augusto, O.2
  • 42
    • 43649084143 scopus 로고    scopus 로고
    • Measurement of NO and NO synthase
    • May; Chapter 7:Unit 7.13
    • Weissman B, Gross S (2001) Measurement of NO and NO synthase. Curr Protoc Neurosci May; Chapter 7:Unit 7.13
    • (2001) Curr Protoc Neurosci
    • Weissman, B.1    Gross, S.2
  • 43
    • 80051675515 scopus 로고    scopus 로고
    • Tetrahydrobiopterin: Biochemistry and pathophysiology
    • 21867484 10.1042/BJ20110293 1:CAS:528:DC%2BC3MXhtFSmtbnF
    • Werner ER, Blau N, Thony B (2011) Tetrahydrobiopterin: biochemistry and pathophysiology. Biochem J 438:397-414
    • (2011) Biochem J , vol.438 , pp. 397-414
    • Werner, E.R.1    Blau, N.2    Thony, B.3
  • 44
    • 12244264207 scopus 로고    scopus 로고
    • NOS inhibition increases bubble formation and reduces survival in sedentary but not exercised rats
    • 12527743 10.1113/jphysiol.2002.030338 1:CAS:528:DC%2BD3sXitVWqsrg%3D
    • Wisloff U, Richardson RS, Brubakk AO (2003) NOS inhibition increases bubble formation and reduces survival in sedentary but not exercised rats. J Physiol 546:577-582
    • (2003) J Physiol , vol.546 , pp. 577-582
    • Wisloff, U.1    Richardson, R.S.2    Brubakk, A.O.3
  • 45
    • 1642565831 scopus 로고    scopus 로고
    • Exercise and nitric oxide prevent bubble formation: A novel approach to the prevention of decompression sickness?
    • 14724207 10.1113/jphysiol.2003.055467 1:CAS:528:DC%2BD2cXivFCmt7o%3D
    • Wisloff U, Richardson RS, Brubakk AO (2004) Exercise and nitric oxide prevent bubble formation: a novel approach to the prevention of decompression sickness? J Physiol 555:825-829
    • (2004) J Physiol , vol.555 , pp. 825-829
    • Wisloff, U.1    Richardson, R.S.2    Brubakk, A.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.