-
1
-
-
84867087508
-
A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation
-
23027613 10.1002/emmm.201201272 1:CAS:528:DC%2BC38XhsVeiur7O
-
Cheng X.; Wang J.; Xia N.; Yan X. X.; Tang T. T.; Chen H.; Zhang H. J.; Liu J.; Kong W.; Sjöberg S.; Folco E.; Libby P.; Liao Y. H.; Shi G. P. A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation. EMBO Mol. Med. 4: 1112-1125; 2012.
-
(2012)
EMBO Mol. Med.
, vol.4
, pp. 1112-1125
-
-
Cheng, X.1
Wang, J.2
Xia, N.3
Yan, X.X.4
Tang, T.T.5
Chen, H.6
Zhang, H.J.7
Liu, J.8
Kong, W.9
Sjöberg, S.10
Folco, E.11
Libby, P.12
Liao, Y.H.13
Shi, G.P.14
-
2
-
-
84866076374
-
Leptin revisited: Its mechanism of action and potential for treating diabetes
-
22935803 10.1038/nrd3757 1:CAS:528:DC%2BC38Xht1ynt7vK
-
Coppari R.; Bjørbæk C. Leptin revisited: its mechanism of action and potential for treating diabetes. Nat. Rev. Drug Discov. 11: 692-708; 2012.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 692-708
-
-
Coppari, R.1
Bjørbæk, C.2
-
3
-
-
0035124840
-
Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity
-
11169977 10.1002/1097-4652(2001)9999:9999<000: AID-JCP1038>3.0. CO;2-T 1:CAS:528:DC%2BD3MXhtVGis7g%3D
-
Cousin B.; André M.; Casteilla L.; Pénicaud L. Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity. J. Cell. Physiol. 186: 380-386; 2001.
-
(2001)
J. Cell. Physiol.
, vol.186
, pp. 380-386
-
-
Cousin, B.1
André, M.2
Casteilla, L.3
Pénicaud, L.4
-
4
-
-
0035095953
-
Leptin directly induces the secretion of interleukin 1 receptor antagonist in human monocytes
-
11158047 10.1210/jc.86.2.783 1:CAS:528:DC%2BD3MXht1KntLk%3D
-
Gabay C.; Dreyer M.; Pellegrinelli N.; Chicheportiche R.; Meier C. A. Leptin directly induces the secretion of interleukin 1 receptor antagonist in human monocytes. J. Clin. Endocrinol. Metab. 86: 783-791; 2001.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 783-791
-
-
Gabay, C.1
Dreyer, M.2
Pellegrinelli, N.3
Chicheportiche, R.4
Meier, C.A.5
-
5
-
-
76249095169
-
Development of monocytes, macrophages, and dendritic cells
-
20133564 10.1126/science.1178331 1:CAS:528:DC%2BC3cXhtlyhsrw%3D
-
Geissmann F.; Manz M. G.; Jung S.; Sieweke M. H.; Merad M.; Ley K. Development of monocytes, macrophages, and dendritic cells. Science 327: 656-661; 2010.
-
(2010)
Science
, vol.327
, pp. 656-661
-
-
Geissmann, F.1
Manz, M.G.2
Jung, S.3
Sieweke, M.H.4
Merad, M.5
Ley, K.6
-
6
-
-
0037265240
-
Alternative activation of macrophages
-
12511873 10.1038/nri978 1:CAS:528:DC%2BD3sXovVw%3D
-
Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 3: 23-35; 2003.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 23-35
-
-
Gordon, S.1
-
7
-
-
36049051889
-
Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis
-
17728393 10.1152/ajpcell.00062.2007 1:CAS:528:DC%2BD2sXhtlentbfL
-
Gruen M. L.; Hao M.; Piston D. W.; Hasty A. H. Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis. Am. J. Physiol. Cell Physiol. 293: C1481-C1488; 2007.
-
(2007)
Am. J. Physiol. Cell Physiol.
, vol.293
-
-
Gruen, M.L.1
Hao, M.2
Piston, D.W.3
Hasty, A.H.4
-
9
-
-
65649141678
-
Leptin enhances CC-chemokine ligand expression in cultured murine macrophage
-
19409880 10.1016/j.bbrc.2009.04.121 1:CAS:528:DC%2BD1MXmsVCru7g%3D
-
Kiguchi N.; Maeda T.; Kobayashi Y.; Fukazawa Y.; Kishioka S. Leptin enhances CC-chemokine ligand expression in cultured murine macrophage. Biochem. Biophys. Res. Commun. 384: 311-315; 2009.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.384
, pp. 311-315
-
-
Kiguchi, N.1
Maeda, T.2
Kobayashi, Y.3
Fukazawa, Y.4
Kishioka, S.5
-
10
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
17200717 10.1172/JCI29881 1:CAS:528:DC%2BD2sXmvV2quw%3D%3D
-
Lumeng C. N.; Bodzin J. L.; Saltiel A. R. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest. 117: 175-184; 2007.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
11
-
-
58149347227
-
Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
-
18829989 10.2337/db08-0872 1:CAS:528:DC%2BD1MXhsleisbY%3D
-
Lumeng C. N.; DelProposto J. B.; Westcott D. J.; Saltiel A. R. Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes 57: 3239-3246; 2008.
-
(2008)
Diabetes
, vol.57
, pp. 3239-3246
-
-
Lumeng, C.N.1
Delproposto, J.B.2
Westcott, D.J.3
Saltiel, A.R.4
-
12
-
-
70350011800
-
Expression patterns of leptin receptor (OB-R) isoforms and direct in vitro effects of recombinant leptin on OB-R, leptin expression and cytokine secretion by human hematopoietic malignant cells
-
19665393 10.1016/j.cyto.2009.07.006 1:CAS:528:DC%2BD1MXhtlWnsrzI
-
Mouzaki A.; Panagoulias I.; Dervilli Z.; Zolota V.; Spadidea P.; Rodi M.; Panitsas F. P.; Lagadinou E.; de Lastic A. L.; Georgakopoulos T. Expression patterns of leptin receptor (OB-R) isoforms and direct in vitro effects of recombinant leptin on OB-R, leptin expression and cytokine secretion by human hematopoietic malignant cells. Cytokine 48: 203-211; 2009.
-
(2009)
Cytokine
, vol.48
, pp. 203-211
-
-
Mouzaki, A.1
Panagoulias, I.2
Dervilli, Z.3
Zolota, V.4
Spadidea, P.5
Rodi, M.6
Panitsas, F.P.7
Lagadinou, E.8
De Lastic, A.L.9
Georgakopoulos, T.10
-
13
-
-
0032102990
-
Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: Competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype
-
9605134 1:CAS:528:DyaK1cXjt1Gnu7s%3D
-
Munder M.; Eichmann K.; Modolell M. Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype. J.Immunol. 160: 5347-5354; 1998.
-
(1998)
J.Immunol.
, vol.160
, pp. 5347-5354
-
-
Munder, M.1
Eichmann, K.2
Modolell, M.3
-
14
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
-
17916553 10.1074/jbc.M706762200 1:CAS:528:DC%2BD2sXhtlCrtLzP
-
Nguyen M. T.; Favelyukis S.; Nguyen A. K.; Reichart D.; Scott P. A.; Jenn A.; Liu-Bryan R.; Glass C. K.; Neels J. G.; Olefsky J. M. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J. Biol. Chem. 282: 35279-35292; 2007.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35279-35292
-
-
Nguyen, M.T.1
Favelyukis, S.2
Nguyen, A.K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
15
-
-
84864244872
-
Metabolic syndrome, insulin resistance, and roles of inflammation - Mechanisms and therapeutic targets
-
22815343 10.1161/ATVBAHA.111.241869 1:CAS:528:DC%2BC38XhtVCrsLnP
-
Romeo G. R.; Lee J.; Shoelson S. E. Metabolic syndrome, insulin resistance, and roles of inflammation - mechanisms and therapeutic targets. Arterioscler. Thromb. Vasc. Biol. 32: 1771-1776; 2012.
-
(2012)
Arterioscler. Thromb. Vasc. Biol.
, vol.32
, pp. 1771-1776
-
-
Romeo, G.R.1
Lee, J.2
Shoelson, S.E.3
-
16
-
-
84874263229
-
Association with leptin gene c.-2548 G>A polymorphism, serum leptin levels, and body mass index in Turkish obese patients
-
10.1007/s12013-012-9427-1
-
Sahin D. S.; Tumer C.; Demir C.; Celik M. M.; Celik M.; Ucar E.; Gunesacar R. Association with leptin gene c.-2548 G>A polymorphism, serum leptin levels, and body mass index in Turkish obese patients. Cell. Biochem. Biophys. 2012. doi: 10.1007/s12013-012-9427-1.
-
(2012)
Cell. Biochem. Biophys.
-
-
Sahin, D.S.1
Tumer, C.2
Demir, C.3
Celik, M.M.4
Celik, M.5
Ucar, E.6
Gunesacar, R.7
-
17
-
-
0033602850
-
Human leptin stimulates proliferation and activation of human circulating monocytes
-
10357875 10.1006/cimm.1999.1490 1:CAS:528:DyaK1MXjsFWnsr0%3D
-
Santos-Alvarez J.; Goberna R.; Sánchez-Margalet V. Human leptin stimulates proliferation and activation of human circulating monocytes. Cell. Immunol. 194: 6-11; 1999.
-
(1999)
Cell. Immunol.
, vol.194
, pp. 6-11
-
-
Santos-Alvarez, J.1
Goberna, R.2
Sánchez-Margalet, V.3
-
18
-
-
34548665750
-
Expression of the leptin receptor in different types of vascular lesions
-
17680264 10.1007/s00418-007-0319-1 1:CAS:528:DC%2BD2sXhtVCntrjJ
-
Schroeter M. R.; Schneiderman J.; Schumann B.; Glückermann R.; Grimmas P.; Buchwald A. B.; Tirilomis T.; Schöndube F. A.; Konstantinides S. V.; Schäfer K. Expression of the leptin receptor in different types of vascular lesions. Histochem. Cell Biol. 128: 323-333; 2007.
-
(2007)
Histochem. Cell Biol.
, vol.128
, pp. 323-333
-
-
Schroeter, M.R.1
Schneiderman, J.2
Schumann, B.3
Glückermann, R.4
Grimmas, P.5
Buchwald, A.B.6
Tirilomis, T.7
Schöndube, F.A.8
Konstantinides, S.V.9
Schäfer, K.10
-
19
-
-
77951822653
-
Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet-induced obesity in mice
-
20185806 10.2337/db09-1402 1:CAS:528:DC%2BC3cXmtFegsbg%3D
-
Shaul M. E.; Bennett G.; Strissel K. J.; Greenberg A. S.; Obin M. S. Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet-induced obesity in mice. Diabetes 59: 1171-1181; 2010.
-
(2010)
Diabetes
, vol.59
, pp. 1171-1181
-
-
Shaul, M.E.1
Bennett, G.2
Strissel, K.J.3
Greenberg, A.S.4
Obin, M.S.5
-
20
-
-
84857883847
-
Macrophage plasticity and polarization: In vivo veritas
-
10.1172/JCI59643 1:CAS:528:DC%2BC38XjsV2ms7g%3D
-
Sica A.; Mantovani A. Macrophage plasticity and polarization: in vivo veritas. Clin. Investig. 122: 787-795; 2012.
-
(2012)
Clin. Investig.
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
21
-
-
26244448904
-
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor alpha
-
16123319 10.1161/01.ATV.0000183883.72263.13 1:CAS:528:DC%2BD2MXhtVCltrnK
-
Suganami T.; Nishida J.; Ogawa Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler. Thromb. Vasc. Biol. 25: 2062-2068; 2005.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 2062-2068
-
-
Suganami, T.1
Nishida, J.2
Ogawa, Y.3
-
22
-
-
1542379725
-
Leptin-deficient mice are protected from accelerated nephrotoxic nephritis
-
14742244 10.1016/S0002-9440(10)63128-8 1:CAS:528:DC%2BD2cXhsFGqs7w%3D
-
Tarzi R. M.; Cook H. T.; Jackson I.; Pusey C. D.; Lord G. M. Leptin-deficient mice are protected from accelerated nephrotoxic nephritis. Am. J. Pathol. 164: 385-390; 2004.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 385-390
-
-
Tarzi, R.M.1
Cook, H.T.2
Jackson, I.3
Pusey, C.D.4
Lord, G.M.5
-
24
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
16341265 10.1172/JCI24335 1:CAS:528:DC%2BD28XjslOhsw%3D%3D
-
Weisberg S. P.; Hunter D.; Huber R.; Lemieux J.; Slaymaker S.; Vaddi K.; Charo I.; Leibel R. L.; Ferrante Jr. A. W. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J. Clin. Invest. 116: 115-124; 2006.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
Lemieux, J.4
Slaymaker, S.5
Vaddi, K.6
Charo, I.7
Leibel, R.L.8
Ferrante Jr., A.W.9
-
25
-
-
34548354722
-
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
-
10.1038/sj.ijo.0803632 1:CAS:528:DC%2BD2sXpsF2qurs%3D
-
Zeyda M.; Farmer D.; Todoric J.; Aszmann O.; Speiser M.; Györi G.; Zlabinger G. J.; Stulnig T. M. Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int. J. Obes. 31: 1420-1428; 2007.
-
(2007)
Int. J. Obes.
, vol.31
, pp. 1420-1428
-
-
Zeyda, M.1
Farmer, D.2
Todoric, J.3
Aszmann, O.4
Speiser, M.5
Györi, G.6
Zlabinger, G.J.7
Stulnig, T.M.8
-
26
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
7984236 10.1038/372425a0 1:CAS:528:DyaK2MXisVGqsbs%3D
-
Zhang Y.; Proenca R.; Maffei M.; Barone M.; Leopold L.; Friedman J. M. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432; 1994.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
|