Different Immunity Elicited by Recombinant H5N1 Hemagglutinin Proteins Containing Pauci-Mannose, High-Mannose, or Complex Type N-Glycans

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Lin, Shih Chang ^a   Jan, Jia Tsrong ^b   Dionne, Ben ^c   Butler, Michael ^c   Huang, Ming Hsi ^d   Wu, Chung Yi ^b   Wong, Chi Huey ^b   Wu, Suh Chin ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c UNIVERSITY OF MANITOBA   (Canada)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCAN; IMMUNOGLOBULIN G ANTIBODY; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; MANNOSE; N GLYCAN; RECOMBINANT PROTEIN; SIALIDASE; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNIZATION; INFLUENZA A (H5N1); INFLUENZA VIRUS A H5N1; INSECT CELL; MAMMAL CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SIALYLATION; TREATMENT OUTCOME; VIRUS IMMUNITY; VIRUS NEUTRALIZATION;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIBODY-PRODUCING CELLS; ANTIGEN-PRESENTING CELLS; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CHO CELLS; CRICETINAE; CRICETULUS; FEMALE; GLYCOSYLATION; HEMAGGLUTININS; HUMANS; IMMUNOGLOBULIN ISOTYPES; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA VACCINES; INFLUENZA, HUMAN; MANNANS; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; SF9 CELLS; SPODOPTERA; T-LYMPHOCYTES; VACCINATION; VIRAL PROTEINS;

AVES; HEXAPODA; MAMMALIA; MUS; ORTHOMYXOVIRIDAE; TETRA;

EID: 84879177723     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066719     Document Type: Article

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