Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle

Physiological Genomics

Volumn 45, Issue 12, 2013, Pages 477-486

  Banduseela, Varuna C ^a   Chen, Yi Wen ^b,c   Kultima, Hanna Göransson ^a   Norman, Holly S ^a,d   Aare, Sudhakar ^a   Radell, Peter ^e   Eriksson, Lars I ^e   Hoffman, Eric P ^b,c   Larsson, Lars ^a,f  

^a UPPSALA UNIVERSITY   (Sweden)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^e KAROLINSKA INSTITUTE   (Sweden)

^f PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Autophagy; Chaperones; Critical illness myopathy and skeletal muscle proteostasis; Intensive care unit; Porcine ICU model; Protein synthesis; Skeletal muscle

Indexed keywords

CHAPERONE; CORTICOSTEROID; NEUROMUSCULAR BLOCKING AGENT; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; AUTOPHAGY; CRITICAL ILLNESS; CRITICAL ILLNESS MYOPATHY; DOWN REGULATION; FEMALE; IMMOBILIZATION; INTENSIVE CARE UNIT; MUSCLE WEAKNESS; MYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; PROTEIN SYNTHESIS; SEDATION; SKELETAL MUSCLE;

AUTOPHAGY; CHAPERONES; CRITICAL ILLNESS MYOPATHY AND SKELETAL MUSCLE PROTEOSTASIS; INTENSIVE CARE UNIT; PORCINE ICU MODEL; PROTEIN SYNTHESIS; SKELETAL MUSCLE;

ANIMALS; AUTOPHAGY; CRITICAL ILLNESS; CYTOSKELETON; DENSITOMETRY; DOWN-REGULATION; ENDOPLASMIC RETICULUM; FEMALE; HEAT-SHOCK PROTEINS; IMMUNOBLOTTING; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; MUSCULAR DISEASES; OXIDATIVE STRESS; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; SUS SCROFA; UP-REGULATION;

SUIDAE; SUS;

EID: 84879176701     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00141.2012     Document Type: Article

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