-
1
-
-
77956996035
-
Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus
-
Acharya R, Carnevale V, Fiorin G, Levine BG, Polishchuk AL, Balannik V, Samish I, Lamb RA, Pinto LH, DeGrado WF, Klein ML. Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus. Proc Natl Acad Sci USA 107: 15075-15080, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15075-15080
-
-
Acharya, R.1
Carnevale, V.2
Fiorin, G.3
Levine, B.G.4
Polishchuk, A.L.5
Balannik, V.6
Samish, I.7
Lamb, R.A.8
Pinto, L.H.9
Degrado, W.F.10
Klein, M.L.11
-
2
-
-
38949212212
-
Misfolding of the cystic fibrosis transmembrane conductance regulator and disease
-
Cheung JC, Deber CM. Misfolding of the cystic fibrosis transmembrane conductance regulator and disease. Biochemistry 47: 1465-1473, 2008.
-
(2008)
Biochemistry
, vol.47
, pp. 1465-1473
-
-
Cheung, J.C.1
Deber, C.M.2
-
4
-
-
84866344890
-
The role of CFTR in transepithelial liquid transport in pig alveolar epithelia
-
Collawn JF, Matalon S. The role of CFTR in transepithelial liquid transport in pig alveolar epithelia. Am J Physiol Lung Cell Mol Physiol 303: L489-L491, 2012. 5
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Collawn, J.F.1
Matalon, S.2
-
6
-
-
84855338066
-
Transgenic hCFTR expression fails to correct β-ENaC mouse lung disease
-
Grubb BR, O'Neal WK, Ostrowski LE, Kreda SM, Button B, Boucher RC. Transgenic hCFTR expression fails to correct β-ENaC mouse lung disease. Am J Physiol Lung Cell Mol Physiol 302: L238-L247, 2012.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
-
-
Grubb, B.R.1
O'Neal, W.K.2
Ostrowski, L.E.3
Kreda, S.M.4
Button, B.5
Boucher, R.C.6
-
7
-
-
84866361922
-
Does the F508-CFTR mutation induce a proinflammatory response in human airway epithelial cells?
-
Hampton TH, Ballok AE, Bomberger JM, Rutkowski MR, Barnaby R, Coutermarsh B, Conejo-Garcia JR, O'Toole GA, Stanton BA. Does the F508-CFTR mutation induce a proinflammatory response in human airway epithelial cells? Am J Physiol Lung Cell Mol Physiol 303: L509-L518, 2012.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Hampton, T.H.1
Ballok, A.E.2
Bomberger, J.M.3
Rutkowski, M.R.4
Barnaby, R.5
Coutermarsh, B.6
Conejo-Garcia, J.R.7
O'Toole, G.A.8
Stanton, B.A.9
-
8
-
-
84871362534
-
Incidence of viral respiratory pathogens causing exacerbations in adult cystic fibrosis patients
-
Hoek RA, Paats MS, Pas SD, Bakker M, Hoogsteden HC, Boucher CA, van der Eerden MM. Incidence of viral respiratory pathogens causing exacerbations in adult cystic fibrosis patients. Scand J Infect Dis 45: 65-69, 2013.
-
(2013)
Scand J Infect Dis
, vol.45
, pp. 65-69
-
-
Hoek, R.A.1
Paats, M.S.2
Pas, S.D.3
Bakker, M.4
Hoogsteden, H.C.5
Boucher, C.A.6
van der Eerden, M.M.7
-
10
-
-
80055114128
-
Phosphatidylinositol 4,5-bisphosphate stimulates alveolar epithelial fluid clearance in male and female adult rats
-
Kooijman EE, Kuzenko SR, Gong D, Best MD, Folkesson HG. Phosphatidylinositol 4,5-bisphosphate stimulates alveolar epithelial fluid clearance in male and female adult rats. Am J Physiol Lung Cell Mol Physiol 301: L804-L811, 2011.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.301
-
-
Kooijman, E.E.1
Kuzenko, S.R.2
Gong, D.3
Best, M.D.4
Folkesson, H.G.5
-
11
-
-
70350524014
-
Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species
-
Lazrak A, Iles KE, Liu G, Noah DL, Noah JW, Matalon S. Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species. FASEB J 23: 3829-3842, 2009.
-
(2009)
FASEB J
, vol.23
, pp. 3829-3842
-
-
Lazrak, A.1
Iles, K.E.2
Liu, G.3
Noah, D.L.4
Noah, J.W.5
Matalon, S.6
-
12
-
-
80053376536
-
Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung
-
Lazrak A, Jurkuvenaite A, Chen L, Keeling KM, Collawn JF, Bedwell DM, Matalon S. Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung. Am J Physiol Lung Cell Mol Physiol 301: L557-L567, 2011.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.301
-
-
Lazrak, A.1
Jurkuvenaite, A.2
Chen, L.3
Keeling, K.M.4
Collawn, J.F.5
Bedwell, D.M.6
Matalon, S.7
-
13
-
-
84863897013
-
CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia
-
Li X, Comellas AP, Karp PH, Ernst SE, Moninger TO, Gansemer ND, Taft PJ, Pezzulo AA, Rector MV, Rossen N, Stoltz DA, McCray PB Jr, Welsh MJ, Zabner J. CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia. Am J Physiol Lung Cell Mol Physiol 303: L152-L160, 2012.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Li, X.1
Comellas, A.P.2
Karp, P.H.3
Ernst, S.E.4
Moninger, T.O.5
Gansemer, N.D.6
Taft, P.J.7
Pezzulo, A.A.8
Rector, M.V.9
Rossen, N.10
Stoltz, D.A.11
McCray Jr., P.B.12
Welsh, M.J.13
Zabner, J.14
-
14
-
-
84878234654
-
Loss of Cftr function exacerbates the phenotype of Na_ hyperabsorption in murine airways
-
Livraghi-Butrico A, Kelly EJ, Wilkinson KJ, Rogers TD, Gilmore RC, Harkema JR, Randell SH, Boucher RC, O'Neal WK, Grubb BR. Loss of Cftr function exacerbates the phenotype of Na_ hyperabsorption in murine airways. Am J Physiol Lung Cell Mol Physiol 304: (7) L469-L480, 2013.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.304
, Issue.7
-
-
Livraghi-Butrico, A.1
Kelly, E.J.2
Wilkinson, K.J.3
Rogers, T.D.4
Gilmore, R.C.5
Harkema, J.R.6
Randell, S.H.7
Boucher, R.C.8
O'Neal, W.K.9
Grubb, B.R.10
-
15
-
-
84878645367
-
Influenza matrix protein 2 alters CFTR expression and function through its ion channel activity
-
Londino JD, Lazrak A, Jurkuvenaite A, Collawn JF, Noah JW, Matalon S. Influenza matrix protein 2 alters CFTR expression and function through its ion channel activity. Am J Physiol Lung Cell Mol Physiol 304: 582-592, 2013.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.304
, pp. 582-592
-
-
Londino, J.D.1
Lazrak, A.2
Jurkuvenaite, A.3
Collawn, J.F.4
Noah, J.W.5
Matalon, S.6
-
16
-
-
0033066855
-
Sodium channels in alveolar epithelial cells: Molecular characterization, biophysical properties, and physiological significance
-
Matalon S, O'Brodovich H. Sodium channels in alveolar epithelial cells: molecular characterization, biophysical properties, and physiological significance. Annu Rev Physiol 61: 627-661, 1999.
-
(1999)
Annu Rev Physiol
, vol.61
, pp. 627-661
-
-
Matalon, S.1
O'Brodovich, H.2
-
17
-
-
84863979545
-
Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells
-
Nimishakavi S, Besprozvannaya M, Raymond WW, Craik CS, Gruenert DC, Caughey GH. Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 303: L97-L106, 2012.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Nimishakavi, S.1
Besprozvannaya, M.2
Raymond, W.W.3
Craik, C.S.4
Gruenert, D.C.5
Caughey, G.H.6
-
18
-
-
67649184157
-
Influenza exerts continued pressure in an era of modern medicine
-
Noah JW, Noah DL, Matalon S. Influenza exerts continued pressure in an era of modern medicine. Am J Respir Cell Mol Biol 41: 3-7, 2009.
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 3-7
-
-
Noah, J.W.1
Noah, D.L.2
Matalon, S.3
-
19
-
-
33749259801
-
Bafilomycin A1-sensitive pathway is required for the maturation of cystic fibrosis transmembrane conductance regulator
-
Okiyoneda T, Niibori A, Harada K, Kohno T, Hashimoto Y, Kusuhara H, Takada T, Shuto T, Suico MA, Sugiyama Y, Kai H. Bafilomycin A1-sensitive pathway is required for the maturation of cystic fibrosis transmembrane conductance regulator. Biochim Biophys Acta 1763: 1017-1023, 2006.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 1017-1023
-
-
Okiyoneda, T.1
Niibori, A.2
Harada, K.3
Kohno, T.4
Hashimoto, Y.5
Kusuhara, H.6
Takada, T.7
Shuto, T.8
Suico, M.A.9
Sugiyama, Y.10
Kai, H.11
-
20
-
-
84864297297
-
The challenges and promises of new therapies for cystic fibrosis
-
Pier GB. The challenges and promises of new therapies for cystic fibrosis. J Exp Med 209: 1235-1239, 2012.
-
(2012)
J Exp Med
, vol.209
, pp. 1235-1239
-
-
Pier, G.B.1
-
21
-
-
48149090717
-
Cystic fibrosis: Impaired bicarbonate secretion and mucoviscidosis
-
Quinton PM. Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis. Lancet 372: 415-417, 2008.
-
(2008)
Lancet
, vol.372
, pp. 415-417
-
-
Quinton, P.M.1
-
22
-
-
84871901948
-
A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect
-
Rauh R, Soell D, Haerteis S, Diakov A, Nesterov V, Krueger B, Sticht H, Korbmacher C. A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect. Am J Physiol Lung Cell Mol Physiol 304: L43-L55, 2013.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.304
-
-
Rauh, R.1
Soell, D.2
Haerteis, S.3
Diakov, A.4
Nesterov, V.5
Krueger, B.6
Sticht, H.7
Korbmacher, C.8
-
23
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z, Zielenski J, Lok S, Plavsic N, Chou JL, Drumm ML, Iannuzzi MC, Collins FS, Tsui L-C. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245: 1066-1073, 1989.
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.L.10
Drumm, M.L.11
Iannuzzi, M.C.12
Collins, F.S.13
Tsui, L.-C.14
-
24
-
-
79958746554
-
Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment
-
Rogan MP, Stoltz DA, Hornick DB. Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment. Chest 139: 1480-1490, 2011.
-
(2011)
Chest
, vol.139
, pp. 1480-1490
-
-
Rogan, M.P.1
Stoltz, D.A.2
Hornick, D.B.3
-
25
-
-
78650657069
-
Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells
-
Rubenstein RC, Lockwood SR, Lide E, Bauer R, Suaud L, Grumbach Y. Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 300: L88-L101, 2011.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
-
-
Rubenstein, R.C.1
Lockwood, S.R.2
Lide, E.3
Bauer, R.4
Suaud, L.5
Grumbach, Y.6
-
26
-
-
0029929748
-
The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus
-
Sakaguchi T, Leser GP, Lamb RA. The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus. J Cell Biol 133: 733-747, 1996.
-
(1996)
J Cell Biol
, vol.133
, pp. 733-747
-
-
Sakaguchi, T.1
Leser, G.P.2
Lamb, R.A.3
-
27
-
-
84878245487
-
Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels
-
Sanders CJ, Vogel P, McClaren JL, Bajracharya R, Doherty PC, Thomas PG. Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels. Am J Physiol Lung Cell Mol Physiol 304: (7) L481-L488, 2013.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.304
, Issue.7
-
-
Sanders, C.J.1
Vogel, P.2
McClaren, J.L.3
Bajracharya, R.4
Doherty, P.C.5
Thomas, P.G.6
-
28
-
-
0037425564
-
Mortality associated with influenza and respiratory syncytial virus in the United States
-
Thompson WW, Shay DK, Weintraub E, Brammer L, Cox N, Anderson LJ, Fukuda K. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 289: 179-186, 2003.
-
(2003)
JAMA
, vol.289
, pp. 179-186
-
-
Thompson, W.W.1
Shay, D.K.2
Weintraub, E.3
Brammer, L.4
Cox, N.5
Anderson, L.J.6
Fukuda, K.7
-
29
-
-
84857973847
-
Ubiquitination and proteolysis in acute lung injury
-
Vadasz I, Weiss CH, Sznajder JI. Ubiquitination and proteolysis in acute lung injury. Chest 141: 763-771, 2012.
-
(2012)
Chest
, vol.141
, pp. 763-771
-
-
Vadasz, I.1
Weiss, C.H.2
Sznajder, J.I.3
-
30
-
-
0028006681
-
Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins
-
Ward CL, Kopito RR. Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins. J Biol Chem 269: 25710-25718, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 25710-25718
-
-
Ward, C.L.1
Kopito, R.R.2
-
31
-
-
0027162649
-
Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
-
Welsh MJ, Smith AE. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73: 1251-1254, 1993.
-
(1993)
Cell
, vol.73
, pp. 1251-1254
-
-
Welsh, M.J.1
Smith, A.E.2
|