Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN

Molecular Cancer

Volumn 12, Issue 1, 2013, Pages

  Sharma, Pankaj ^a   Knowell, Ashley Evans ^a   Chinaranagari, Swathi ^a   Komaragiri, Shravan ^a   Nagappan, Peri ^a   Patel, Divya ^a   Havrda, Mathew C ^b,c   Chaudhary, Jaideep ^a  

^a CLARK ATLANTA UNIVERSITY   (United States)

^b NORRIS COTTON CANCER CENTER   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Akt; Androgen receptor; Id4; NKX3.1; Prostate; PTEN

Indexed keywords

ANDROGEN RECEPTOR; INHIBITOR OF DIFFERENTIATION 4; INHIBITOR OF DIFFERENTIATION PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN NKX3.1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; ID4 PROTEIN, HUMAN; IDB4 PROTEIN, MOUSE; NKX3-1 PROTEIN, HUMAN; NKX3-1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MORPHOLOGY; MOUSE; NONHUMAN; PROMOTER REGION; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROTEIN DEPLETION; PROTEIN EXPRESSION; RECEPTOR BINDING; WILD TYPE; ANIMAL; APOPTOSIS; DEFICIENCY; GROWTH, DEVELOPMENT AND AGING; HUMAN; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION; PROSTATE; PROSTATE TUMOR; PROSTATIC INTRAEPITHELIAL NEOPLASIA;

MUS;

ANIMALS; APOPTOSIS; HOMEODOMAIN PROTEINS; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEINS; MALE; MICE; MICE, KNOCKOUT; PHENOTYPE; PHOSPHORYLATION; PROSTATE; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECEPTORS, ANDROGEN; TRANSCRIPTION FACTORS;

EID: 84879082934     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-12-67     Document Type: Article

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