Exercise training enhances cardiac IGFI-R/PI3K/Akt and Bcl-2 family associated pro-survival pathways in streptozotocin-induced diabetic rats

International Journal of Cardiology

Volumn 167, Issue 2, 2013, Pages 478-485

  Cheng, Shiu Min ^a   Ho, Tsung Jung ^b,c   Yang, Ai Lun ^d   Chen, I Ju ^a   Kao, Chung Lan ^e   Wu, Fan Ni ^b   Lin, James A ^b   Kuo, Chia Hua ^b,d   Ou, Hsiu Chung ^b   Huang, Chih Yang ^a,b   Lee, Shin Da ^a,b  

^a ASIA UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

^d UNIVERSITY OF TAIPEI   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Bcl 2; Diabetes; Heart; IGFI R PI3K Akt survival pathway

Indexed keywords

CASPASE 3; CITRATE SYNTHASE; CYTOCHROME C; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

AEROBIC EXERCISE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA FRAGMENTATION; ENZYME ACTIVITY; ENZYME RELEASE; EXERCISE; HEART HEMODYNAMICS; HEART SIZE; HISTOPATHOLOGY; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; SURVIVAL RATE; WESTERN BLOTTING;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; HEART VENTRICLES; INSULIN-LIKE GROWTH FACTOR I; MALE; PHOSPHATIDYLINOSITOL 3-KINASE; PHYSICAL CONDITIONING, ANIMAL; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RANDOM ALLOCATION; RATS; RATS, WISTAR; RECEPTOR, IGF TYPE 1; SURVIVAL RATE;

EID: 84879072829     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.01.031     Document Type: Article

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