Development of oleanane-type triterpenes as a new class of HCV entry inhibitors

Journal of Medicinal Chemistry

Volumn 56, Issue 11, 2013, Pages 4300-4319

  Yu, Fei ^a   Wang, Qi ^a   Zhang, Zhen ^a   Peng, Yiyun ^a   Qiu, Yunyan ^a   Shi, Yongying ^a   Zheng, Yongxiang ^a   Xiao, Sulong ^a   Wang, Han ^a   Huang, Xiaoxi ^a   Zhu, Linyi ^a   Chen, Kunbo ^a   Zhao, Chuanke ^a   Zhang, Chuanling ^a   Yu, Maorong ^a   Sun, Dian ^b   Zhang, Lihe ^a   Zhou, Demin ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CD81 ANTIGEN; GLYCOPROTEIN E2; OLEANOLIC ACID DERIVATIVE; TRITERPENE DERIVATIVE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CARBOHYDRATE ANALYSIS; CONTROLLED STUDY; DRUG ACETYLATION; DRUG BINDING; DRUG CONJUGATION; DRUG HYDROXYLATION; DRUG OXIDATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; GLYCOSYLATION; HEPATITIS C VIRUS; HOST CELL; IC 50; NONHUMAN; PHARMACOPHORE; VIRUS ATTACHMENT; VIRUS ENTRY;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CYTOTOXINS; HEK293 CELLS; HEMOLYTIC AGENTS; HEPACIVIRUS; HUMANS; OLEANOLIC ACID; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS INTERNALIZATION;

EID: 84879063655     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301910a     Document Type: Article

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