The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion

Toxicological Sciences

Volumn 92, Issue 2, 2006, Pages 456-463

  Hussain, Saber M ^a   Javorina, Amanda K ^a   Schrand, Amanda M ^b   Duhart, H M Helen M ^c   Ali, Syed F ^c   Schlager, John J ^a  

^a AIR FORCE RESEARCH LABORATORY   (United States)

^b University of Dayton   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Dopamine; In vitro toxicity; Manganese; Nanoparticles; PC 12 cells

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; DOPAMINE; HOMOVANILLIC ACID; MANGANESE; MANGANESE OXIDE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SILVER; SILVER NITRATE;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; CELL CULTURE; CELL STRAIN; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DISSOLUTION; EXPOSURE; EXTRACELLULAR MATRIX; INTERNALIZATION; MITOCHONDRION; NONHUMAN; NOSE MUCOSA; PHASE CONTRAST MICROSCOPY; PHENOTYPE;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; DOPAMINE; HOMOVANILLIC ACID; MANGANESE COMPOUNDS; NANOSTRUCTURES; OXIDES; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; SILVER;

EID: 33745775422     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfl020     Document Type: Article

References (27)

1. Alinovi, R., Vettori, M. V., Mutti, A., Cavazzini, S., Bacchini, A., and Bergamaschi, E. (1996). Dopamine (DA) metabolism in PC12 cells exposed to manganese (Mn) at different oxidation states. Neurotoxicology 17, 743-750.
2. Almas, B., Le Bourdelles, B., Flatmark, T., Mallet, J., and Haavik, J. (1992). Regulation of recombinant human tyrosine hydroxylase isozymes by catecholamine binding and phosphorylation. Structure/activity studies and mechanistic implications. Eur. J. Biochem. 209, 249-255.
3. Aschner, M., Erikson, K. M., and Dorman, D. C. (2005). Manganese dosimetry: Species differences and implications for neurotoxicity. Crit. Rev. Toxicol. 35, 1-32.
4. Archibald, F. S., and Tyree, C. (1987). Manganese poisoning and the attack of trivalent manganese upon catecholamines. Arch. Biochem. Biophys. 256, 638-650.
5. Braydich-Stolle, L., Hussain, S., Schlager, J., and Hofmann, M. C. (2005). In vitro cytotoxicity of nanoparticles in mammalian germ-line stem cells. Toxicol. Sci. 88, 412-419.
6. Carmichael, J., Degraff, W. G., Gazdar, A. F., Minna, J. D., and Mitchell, J. B. (1987). Evaluation of a tetrazolium-based semi-automated colorimetric assay: Assessment of chemo sensitivity testing. Cancer Res. 47, 936-942.
7. Cui, D., and Gao, H. (2003). Advance and prospect of bionanomaterials. Biotechnol. Prog. 19, 683-692.
8. Furno, F., Morley, K. S., Wong, B., Sharp, B. L., Arnold, P. L., Howdle, S. M., Bayston, R., Brown, P. D., Winship, P. D., and Reid, H. J. (2004). Silver nanoparticles and polymeric medical devices: A new approach to prevention of infection? J. Antimicrob. Chemother. 54, 1019-1024.
9. Han, M. J., Ozaki, T., and Yu, J. (2005). Electronic structure and magnetic properties of small manganese oxide clusters. J. Chem. Phys. 123, 34306.
10. Hurley, L. S. (1981). The roles of trace elements in foetal and neonatal development. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 294(1071), 145-152.
11. Hussain, S., and Ali, S. F. (2002). Zinc potentiates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced dopamine depletion in caudate nucleus of mice brain. Neurosci. Lett. 335, 25-28.
12. Hussain, S., Slikker, W., Jr, and Ali, S. F. (1997). The effects of chronic exposure of manganese on antioxidant enzymes in different regions of rat brain. Neurosci. Res. Commun. 21, 135-144.
13. Hussain, S. M., Hess, K. L., Gearharl, J. M., Geiss, K. T., and Schlager, J. J. (2005). In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicol. In Vitro 19, 975-983.
14. Jayakumar, A. R., Rama Rao, K. V., Kalaiselvi, P., and Norenberg, M. D. (2004). Combined effects of ammonia and manganese on astrocytes in culture. Neurochem. Res. 11, 2051-2056.
15. Lam, C. W., James, J. T., McCluskey, R., and Hunter, R. L. (2004). Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol. Sci. 77, 126-134.
16. Lloyd, R. V. (1995). Mechanism of the manganese-catalyzed autoxidation of dopamine. Chem. Res. Toxicol. 8, 111-116.
17. Monteiro-Riviere, N. A., Nemanich, R. J., Inman, A. O., Wang, Y. Y., and Riviere, J. E. (2005). Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol. Lett. 155, 377-384.
18. Oberdorster, E. (2004). Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass. Environ. Health Perspect. 112, 1058-1062.
19. Oberdorster, G., Gelein, R. M., Ferin, J., and Weiss, B. (1995). Association of particulate air pollution and acute mortality: Involvement of ultrafine particles? Inhal. Toxicol. 7, 111-124.
20. Oberdorster, G., Oberdorster, E., and Oberdorster, J. (2005). Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 113, 823-839.
21. Olanow, C. W. (2004). Manganese-induced parkinsonism and Parkinson's disease. Ann. N. Y. Acad. Sci. 1012, 209-223.
22. 3(+)-induced neurotoxicity of dopamine: Prevention of quinone-derived oxygen toxicity by DT diaphorase and superoxide dismutase. Chem. Biol. Interact. 72, 309-324.
23. Simonian, N. A., and Coyle, J. T. (1996). Oxidative stress in neurodegenerative diseases. Annu. Rev. Pharmacol. Toxicol. 36, 83-106.
24. Velez-Pardo, C., Jimenez Del Rio, M., Verschueren, H., Ebinger, G., and Vauquelin, G. (1997). Dopamine and iron induce apoptosis in PC12 cells. Pharmacol. Toxicol. 80, 76-84.
25. Velez-Pardo, C., Del Rio, M. J., Ebinger, G., and Vauquelin, G. (1998). Monoamine and iron-related toxicity: From "serotonin-binding proteins" to lipid peroxidation and apoptosis in PC12 cells. Gen. Pharmacol. 31, 19-24.
26. Wang, H., and Joseph, J. A. (1999). Quantitating cellular oxidative stress by dicholorofluorescein assay using microplate reader. Free Radic. Biol. Med. 27, 612-616.
27. Wu, X., and Bruchez, M. P. (2004). Labeling cellular targets with semi-conductor quantum dot conjugates. Methods Cell Biol. 75, 171-183.