Endogenous A1 adenosine receptor protects mice from acute ethanol-induced hepatotoxicity

Toxicology

Volumn 309, Issue , 2013, Pages 100-106

  Yang, Ping ^a,d   Wang, Zhongqiu ^b   Zhan, Yibei ^a   Wang, Tao ^a   Zhou, Mengyi ^a   Xia, Lin ^a   Yang, Xiao ^a   Zhang, Jianfa ^a,c  

^a NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b TONGJI UNIVERSITY   (China)

^c NANJING UNIVERSITY   (China)

^d CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

A1AR; Ethanol; Lipogenesis; Liver injury

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ALCOHOL; AMINOTRANSFERASE; DIACYLGLYCEROL ACYLTRANSFERASE 2; FAS ANTIGEN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HISTOPATHOLOGY; LIPID PEROXIDATION; LIPOGENESIS; LIVER; LIVER INJURY; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; RECEPTOR UPREGULATION; SERUM; TRIACYLGLYCEROL BLOOD LEVEL; WILD TYPE; ANIMAL; C57BL MOUSE; DRUG EFFECT; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; TIME;

MUS;

ANIMALS; ETHANOL; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; RECEPTOR, ADENOSINE A1; TIME FACTORS;

EID: 84879017881     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.05.003     Document Type: Article

References (34)

1. Bergheim I., Guo L., Davis M.A., Lambert J.C., Beier J.I., Duveau I., Luyendyk J.P., Roth R.A., Arteel G.E. Metformin prevents alcohol-induced liver injury in the mouse: critical role of plasminogen activator inhibitor-1. Gastroenterology 2006, 130:2099-2112.
2. Carmichael F.J., Saldivia V., Varghese G.A., Israel Y., Orrego H. Ethanol-induced increase in portal blood flow: role of acetate and A1- and A2-adenosine receptors. Am. J. Physiol. 1998, 255:G417-G423.
3. De Minicis S., Brenner D.A. Oxidative stress in alcoholic liver disease: role of NADPH oxidase complex. J. Gastroenterol. Hepatol. 2008, 23:S98-S103.
4. Ethier M.F., Chander V., Dobson J.G. Adenosine stimulates proliferation of human endothelial cells in culture. Am. J. Physiol. 1993, 65:H131-H138.
5. Harrington E.O., Smeglin A., Parks N., Newton J., Rounds S. Adenosine induces endothelial apoptosis by activating protein tyrosine phosphatase: a possible role of p38alpha. Am. J. Physiol. Lung. Cell. Mol. Physiol. 2000, 279:L733-L742.
6. Haug A., Høstmark A.T. Lipoprotein lipases, lipoproteins and tissue lipids in rats fed fish oil or coconut oil. J. Nutr. 1987, 117:1011-1017.
7. Hu S., Shen G., Zhao W., Wang F., Jiang X., Huang D. Paeonol, the main active principles of Paeonia moutan, ameliorates alcoholic steatohepatitis in mice. J. Ethnopharmacol. 2010, 128:100-106.
8. Kim S.J., Jung Y.S., Kwon do.Y., Kim Y.C. Alleviation of acute ethanol-induced liver injury and impaired metabolomics of S-containing substances by betaine supplementation. Biochem. Biophys. Res. Commun. 2008, 368:893-898.
9. Kim J., Kim M., Song J.H., Lee H.T. Endogenous A1 adenosine receptors protect against hepatic ischemia reperfusion injury in mice. Liver Transpl. 2008, 14:845-854.
10. Kurose I., Higuchi H., Kato S., Miura S., Watanabe N., Kamegaya Y., Tomita K., Takaishi M., Horie Y., Fukuda M., Mizukami K., Ishii H. Oxidative stress on mitochondria and cell membrane of cultured rat hepatocytes and perfused liver exposed to ethanol. Gastroenterology 1997, 112:1331-1343.
11. Lv X., Chen Z., Li J., Zhang L., Liu H., Huang C., Zhu P. Caffeine protects against alcoholic liver injury by attenuating inflammatory response and oxidative stress. Inflamm. Res. 2010, 59:635-645.
12. Maddrey W.C. Alcohol-induced liver disease. Clin. Liver Dis. 2000, 4:115-131.
13. Masini A., Ceccarelli D., Gallesi D., Giovannini F., Trenti T. Lipid hydroperoxide induced mitochondrial dysfunction following acute ethanol intoxication in rats: the critical role for mitochondrial reduced glutathione. Biochem. Pharmacol. 1994, 47:217-224.
14. Nagy L.E. Molecular aspects of alcohol metabolism: transcription factors involved in early ethanol-induced liver injury. Annu. Rev. Nutr. 2004, 24:55-78.
15. Nordmann R. Alcohol and antioxidant systems. Alcohol. Alcohol. 1994, 29:513-522.
16. Orrego H., Carmichael F.J., Saldivia V., Giles H.G., Sandrin S., Israel Y. Ethanol-induced increase in portal blood flow: role of adenosine. Am. J. Physiol. 1988, 254:G495-G501.
17. Peng Z., Borea P.A., Varani K., Wilder T., Yee H., Chiriboga L., Blackburn M.R., Azzena G., Resta G., Cronstein B.N. Adenosine signaling contributes to ethanol-induced fatty liver in mice. J. Clin. Invest. 2009, 119:582-594.
18. Ralevic V., Burnstock G. Receptors for purines and pyrimidines. Pharmacol. Res. 1998, 50:413-492.
19. Rouach H., Fataccioli V., Gentil M., French S.W., Morimoto M., Nordmann R. Effect of chronic ethanol feeding on lipid peroxidation and protein oxidation in relation to liver pathology. Hepatology 1997, 25:351-355.
20. Rounds S., Yee W.L., Dawicki D.D., Harrington E., Parks N., Cutaia M.V. Mechanism of extracellular ATP- and adenosine-induced apoptosis of cultured pulmonary artery endothelial cells. Am. J. Physiol. 1998, 275:L379-L388.
21. Shaw S., Rubin K.P., Lieber C.S. Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease. Evidence of lipid peroxidation. Dig. Dis. Sci. 1983, 28:585-589.
22. Song Z., Deaciuc I., Song M., Lee D.Y., Liu Y., Ji X., McClain C. Silymarin protects against acute ethanol-induced hepatotoxicity in mice. Alcohol. Clin. Exp. Res. 2006, 30:407-413.
23. Song Z., Zhou Z., Chen T., Hill D., Kang J., Barve S., McClain C. S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice small star, filled. J. Nutr. Biochem. 2003, 14:591-597.
24. Sun D., Samuelson L.C., Yang T., Huang Y., Paliege A., Saunders T., Briggs J., Schnermann J. Mediation of tubuloglomerular feed-back by adenosine: Evidence from mice lacking adenosine 1 receptors. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:9983-9988.
25. Vallon V., Mühlbauer B., Osswald H. Adenosine and kidney function. Physiol. Rev. 2006, 86:901-940.
26. Wada S., Yamazaki T., Kawano Y., Miura S., Ezaki O. Fish oil fed prior to ethanol administration prevents acute ethanol-induced fatty liver in mice. J. Hepatol. 2008, 49:441-450.
27. Wieland P., Lauterburg B.H. Oxidation of mitochondrial proteins and DNA following administration of ethanol. Biochem. Biophys. Res. Commun. 1995, 213:815-819.
28. Wu D., Cederbaum A.I. Oxidative stress and alcoholic liver disease. Semin. Liver Dis. 2009, 29:141-154.
29. Wu K.C., Liu J., Klaassen C.D. Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation. Toxicol. Appl. Pharmacol. 2012, 262:321-329.
30. Yang P., Han Z., Chen P., Zhu L., Wang S., Hua Z., Zhang J. A contradictory role of A1 adenosine receptor in carbon tetrachloride- and bile duct ligation-induced liver fibrosis in mice. J. Pharmacol. Exp. Ther. 2010, 332:747-754.
31. 1 adenosine receptor attenuates alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice. Toxicol. Sci. 2013, 131(1):128-138.
32. Yang R., Han X., Delude R.L., Fink M.P. Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice. J. Lab. Clin. Med. 2003, 142(5):322-331.
33. Yang X., Dong C., Ren G. Effect of soyasaponins-rich extract from soybean on acute alcohol-induced hepatotoxicity in mice. J. Agric. Food Chem. 2011, 59:1138-1144.
34. Zeng T., Xie K.Q. Ethanol and liver: recent advances in the mechanisms of ethanol-induced hepatosteatosis. Arch. Toxicol. 2009, 83:1075-1081.